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Triple Quadrupole Mass Spectrometer Innovation with Integrity f MASS SPECTROMETRY

A game changer creates such a disruptive advantage, it transforms the accepted rules The EVOQ triple quadrupole for liquid chromatography (LC-TQ) was designed for a singular purpose – to reliably quantify thousands of real samples in the fastest sample-to-report time possible. It delivers exceptional sensitivity, precision, accuracy, linearity, and a wide dynamic range for your multiple reaction monitoring (MRM) assays. Innovations in software and atmospheric pressure ionization (API) technology make it a game changer for routine high-sensitivity, quantitative analysis. Easily obtain...

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Food testing requires fast results because of the perishable nature of food. The EVOQ LC-TQ delivers the fastest sample-to-report time using PACERTM software. Environmental analysis can be made costeffective by using on-line extraction (OLE) using the space-saving AdvanceTM UHPLC with OLE. Toxicology testing covers a wide range of compounds in difficult matrices, which can be easily ionized by VIP heated-ESI technology. Pharmacokinetics in early drug discovery requires high-sensitivity and exceptional robustness to analyze hundreds of rat plasma samples on a daily basis; a task easily...

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Bruker Liquid Chromatography Solutions The Advance UHPLC, HPLC, and OLE LC modules By engineering the lowest possible system delay-volume, the Advance LC pump technology delivers superior ballistic gradient reproducibility at analytical flow rates. This design-for-purpose detail minimizes gradient delay and ensures highly precise retention times. The benefit is shorter run-to-run cycle times with the reproducibility required for quantitative LC-MS/MS analyses. The OLE module extends the LC-TQ performance by enabling method-driven, on-line cleanup or sample pre-concentration. The addition of...

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PRECISON, ACCURACY, SPEED, LINEARITY, DYNAMIC RANGE W Sensitivity & Robustness Your assay demands both because real samples have more matrix than analyte.The EVOQ API interface was engineered to deliver sensitivity with uncompromised robustness; requirements that set the standards for accuracy, precision, and Duty cycle impacts sensitivity, accuracy, and precision, and is defined as the time spent by the mass analyzer measuring the target analyte. In MRM, the duty cycle can be close to 100% for a single component. Even with a co-eluting internal standard, the duty cycle of aTQ-MS is much...

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Delivering Heat Where It Belongs Simply set the nebulizer temperature and let VIP technology take over the responsibility of ensuring precise heated the electrospray ionization (ESI) for maximum sensitivity. VIP a patent-pending heated , ESI design that efficiently ionizes thermally labile molecules such as N-oxides, glucuronides, or peptides during the high flow rate heated ESI process. This innovative technology provides an insulated flow path for the LC eluent shielding it from undesirable temperature fluctuations occurring during the LC gradient. High-efficiency ceramic heater...

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Detector This innovative detector design (US Patent 7855361) eliminates the need for a conversion dynode which allows for highly sensitive negative ion detection and fast switching capability.

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Lens-free Design Covered by US Patent 6576897 this unique feature improves , MRM sensitivity by significantly reducing ion scattering losses in the quadrupoles before and after the collision cell. Orifice Interface The EVOQ was designed to be highly sensitive, robust, and simple to operate with low maintenance requirements. The orifice design ensures that the ions traverse the opening into the vacuum chamber and come under the influence of the IQ dual ion funnel system in the fastest time possible. A hot counter-current drying gas (cone gas) guards against stray droplets entering the vacuum...

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Tune-free Ion Optics An elegantly simple design that captures ions in the free-jet expansion region and efficiently focuses them into a coherent ion beam to deliver high sensitivity and robustness without the need for compound-specific tuning. The IQ dual ion funnel system produces two key benefits: 1. ase-of-use, due to the funnel-shaped, RF-only focusing field design E which concentrates the ions into a coherent ion beam, eliminating the need for compound-dependent tuning. 2. ramatically improves instrument up-time and eliminates the need D for frequent maintenance due to the spatial...

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Performancedriven Software Are You Drowning in Data? For years your vendor kept delivering hardware that promised to run more samples per day, using automated sample preparation and ballistic gradients. Yet, your productivity did not increase. Why? They forgot that the vital process of data analysis and review was still dependent on redundant levels of human interaction to ensure data quality. They simply shifted the bottleneck – they failed to satisfy your need for increased efficiency. Hardware is only half the solution and their solution left you drowning in data. Imagine an innovation...

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PACER SOFTWARE © Exception-based Data Review The powerful PACER integration algorithms use pattern-recognition technology to accurately define and integrate small peaks within noisy baselines, a challenge that increases as you approach the LOQ. By accurately picking peaks on the large majority of components, the human workload for review and manual integration is dramatically reduced. This is important because the highlighted chromatograms are the ones that influence assay quality and your In a commercial testing laboratory, we understand time is critical and data quality is paramount....

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For over 50 years Bruker has embodied innovation with integrity as demonstrated by its development of world-class scientific instruments. Today we are pioneering the migration of technology from research to the commercial laboratory. The EVOQ Elite and the EVOQ Qube reflect this design philosophy and solve the hardware and software challenges faced by the quantitative analysis community. Experience the game changing performance of the EVOQ LC-TQ; experience the innovation from Bruker. For research use only. Not for use in diagnostic procedures. Bruker Daltonics is continually improving its...

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