Flow Chemistry
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Flow Chemistry through Mechanochemical Synthesis Green chemistry Fully scalable Novel, patented technology

FLOW CHEMISTRY In Flow Chemistry, chemical processes are taking place in a continuously flowing stream contrary to batch production. This offers several compelling advantages that can be highly beneficial in various industries. The main advantages are: Better mass and heat transfer Faster reactions Increased quality (conversion, yield and selectivity) Broad scalability Higher sustainability Improved safety due to smaller reaction volume MECHANO CHEMISTRY Mechanochemical reactions are understood to be “chemical transformations initiated or sustained by mechanical force”.1 It is considered as...

THE SOLUTION WAB MECHANOCHEMICAL REACTORS Benefits of mechanochemical reactors with bead mill technology: Highest turbulences due to fast rotational speed up to 6’000 rpm Residence time independent from energy input High and very fast conversion, outstanding yield and selectivity Small reaction chamber with an exceptional surface to volume ratio Processing of dry, liquid, liquid assisted and viscous products Excellent surface renewal of the reactants trough bead mill technology Mechanical forces such as shock, pressure, shear, friction, impact and torsion apply Environmentally friendly by...

TOOLS FOR RESEARCH & DEVELOPMENT DYNO®-MILL RESEARCH LAB Small, efficient, versatile: The ideal starting equipment for Research & Development in mechanochemistry. It delivers high mechanical impacts and creates reproducible and upscalable chemical reactions. Applications and advantages: 80 ml reactor volume for smallest quantities Processing of liquids, solids and powders Heating or cooling via the inlet funnel Easy machine operation and cleaning Parts in contact with product in metal or ceramic Logging of relevant process parameters GMP-conform design ATEX-version available Scale-up...

SCALE-UP: FROM LAB TO PRODUCTION A key-factor after successful product development is the scale-up from laboratory to a pilot or production plant. The WAB specialists support you in scaling up your process. Existing scale-up from milligrams to tons Highest mechanical energy input technology Processing of liquid and viscous products Small reaction chamber with an exceptional surface to volume ratio Parts in contact with product in metal or ceramic High turbulances for exceptional homogeneity ATEX-compliant version available Reactor Volume (litre)

HIGH TEMPERATURE VERSION WAB IMPA°CT REACTOR® The WAB IMPA°CT REACTOR® sets the ultimate benchmark in the field of continuous flow mechanochemistry. An inductive heating system arranged around the accelerators enables direct and efficient heating of the reactants up to +160°C with an accuracy of +/- 0.5°C. Together with the impact beads located in the reactor chamber, the REACTOR is a ground-breaking, user friendly and application-specific ® apparatus for molecular synthesis by means of mechanochemistry. Inductor for in-situ heating, temperature control +/- 0.5°C 0.5 litre reaction chamber...

READY-TO-USE PRODUCTION SOLUTION The WAB IMPA°CT REACTOR® is supplied as a complete process system consisting of an inductively heated mechanochemical reactor, dedicated product pumps, mobile operator control panel and accessories. The control panel provides full flexibility to operate the reactor from hand-mode up to fully automated production mode. It controls and logs all production parameters such a product temperature, product pressure, flow rate, product dosing and many more. TECHNOLOGY ADVANTAGES The WAB IMPA°CT REACTOR® provides several technology advantages: Max. controllable...

APPLICATION FIELDS WAB mechanochemical reactors have proven their positive impact to reduce solvents, energy consumption and toxic waste. They improve the conversion, yield and selectivity of the chemical reactions and optimise reaction costs in various application fields. Food & Beverage Battery materials Crop protection APPLICATION EXAMPLE: PARACETAMOL SYNTHESIS Paracetamol is a drug used to relieve pain and reduce fever. In comparison to current solvent-based productions, the process on the DYNO®-MILL RESEARCH LAB achieved a higher yield while also allowing the complete removal of the...

VANILLIN SYNTHESIS Vanillin is the major component of natural vanilla and an important flavouring agent widely used in the food, beverage, perfume and pharmaceutical industry. Performing the reaction on the DYNO®-MILL RESEARCH LAB and DYNO®-MILL MULTI LAB showed a shorter process time, lower process temperature and higher process productivity. The synthesis was achieved without using a catalyst. DYNO®-MILL RESEARCH LAB and DYNO®-MILL MULTI LAB SCAN THE CODE FOR MORE INFORMATION! www.wab-group.com/en/solutions/ application-cases/vanillin-synthesis/ HYDROGEN PEROXIDE + ISOEUGENOL +...

WOOD CHIPS COMPONENTS SEPARATION Processing and depolymerization of wood waste with our DYNO®-MILL MULTI LAB allows the extraction of cellulose, hemicellulose and lignin. For instance, cellulosic pulps can be used in sectors such as papermaking or for higher value-added products such as cellophane or rayon. Hemicellulose can be used to produce biofuels such as bioethanol. Lignin-based products have been proven effective for fertilising, sand-fixing, as bioactive compounds and as adhesives. Compared to conventional hydrothermal process, less energy and less production time is needed. Hammer...

TRIALS AT WAB Do you want to test your processes with our innovative tools? Our expert team is happy to meet you at our worldwide located Process Technology Centres to carry out your trials and to develop your customised solution. We will support you during the whole process from research to industrial scale-up. ADVANTAGES Research & Development on continuous flow chemistry Mechanochemistry from laboratory to production Highest flexibility to perform trials with your products  processing of liquids, solids, powders and liquid assisted products  product heating and cooling  operation of...