ACQUITY QDa Detector
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SEPAR ATING BE YOND QUE S TION BRINGING T H E POW E R OF MASS DE T EC T ION TO YOU

Having the mass spectral information Years of mass Spectrometry technology innovation new patents and patents pending that address size, ease-of-use and affordability THE ACQUITY QDa DETECTOR IS THE START OF NEW ERAS IN BOTH SEPARATIONS SCIENCE AND ANALYTICAL SCIENTIST INDEPENDENCE. CHARACTERIZE YOUR SEPARATIONS WITH THE INTEGRATION OF MASS DETECTION IN THE SAME WORKFLOW, ANSWERING QUESTIONS BEFORE THEY ARE ASKED. EMPOWER YOUR CHEMISTS WITH THE ANALYTICAL CONFIDENCE OF MASS DETECTION FOR MORE VALUE FROM EVERY ANALYSIS AND MORE PRODUCTIVITY FROM EVERY DAY. n Simply power on, and you’re ready...

you need, for the analytical confidence you demand, was beyond the reach of most. Until now. When you can see only what you are looking at, you might not be seeing the full picture. When you see the full picture, you have the confidence to make informed decisions. What if you could generate quality mass spectral data within your existing workflows, confirm compound identities with certainty, immediately highlight co-elutions, shorten development and project times, and not have to wait for results from a specialist analytical service lab? And what if mass detection was suddenly as familiar...

CHARACT ERIZE YOUR SEPARATION NOW – PDA MEETS QDa Mass detection is widely recognized as a reliable method to derive more meaningful information from your samples, but is not necessarily used by all analytical scientists. Mass detection is an orthogonal, complementary technique to optical detection, allowing you to discriminate between analytes of similar absorbance properties. It enables you to confirm compound identity and purity. And, as it’s also compatible with optical detection, you could benefit from both, in the same sample analysis. With the ACQUITY QDa Detector, you now have...

23 With 23 robust, reliable, and reproducible sub-2-µm column chemistries, Waters’ industryleading UPLC and UPC2 columns define speed, sensitivity, and resolution in the chromatographic laboratory. Make informed decisions. Confirm components with certainty, even at trace levels (circled orange above), or for components with no UV response (circled green above). Minimize the risk of unexpected co-elutions, even for components of similar UV spectral properties (circled blue above). This is the analytical confidence of mass detection. And with the ACQUITY QDa Detector, you now have this...

YOUR WORKFLOW, YOUR WORKFORCE, YOUR WORK DONE P LUG AND P LAY P ERFORMANC E It’s as intuitive as an optical detector with the robustness to handle all of your analyses. Working in harmony with your chromatography, it’s pre-optimized to work with your samples, without the sample-specific or user adjustments typical of traditional mass spectrometers. The most information you can get out of your separation for complete characterization. In synergy with optical detection, you can significantly reduce the chance that a sample component will go undetected. Purposeful innovation that gives you the...

EFFORTLESS INTEGRATION Process, interpret, visualize, and compare the most complex data, and turn it into meaningful information quickly and simply. The ACQUITY QDa Detector is fully compatible with Empower® Software, our industry- leading chromatography data software platform. With integrated optical and mass detector data processing workflows, you can also analyze mass spectral data in the same way as you do PDA data. The ACQUITY QDa Detector is also fully compatible with MassLynx® Software and its suite of data processing application managers. Confirm identities and highlight co-elutions...

FOR PERFORMANCE THAT ADVANCES YOUR LABORATORY. AGAIN. Whether your focus is on advancing healthcare, protecting the environment, safeguarding our food and water supplies, or making new materials, the ACQUITY QDa Detector dramatically improves the capability of your existing analytical or purification system and is your simplest route to reliable, versatile mass detection. M ET HOD DEV ELO PMENT Ensure the most complete separation for quantitative ACQUITY UPLC, UPC 2 and HPLC methods, while minimizing the , number of standards you need to run to confirm the identity and homogeneity of peaks...

[ ACQUIT Y QD a DETECTOR ] SAM P LE P ROFILING Now you can combine quantitative and qualitative data into the same workflow with complementary optical and mass detection. Confirm the identities of your additives or specified impurities and even fingerprint unidentified or unspecified impurities – in the same analysis, with the same chromatography, and in the same data processing workflow as your current UV quantification – without the need to run confirmatory standards. In short – know what you quantify. Glucosamine ACQUITY UPLC PDA Detector 195 nm In this nutraceutical formulation,...

FOR DECISIONS THAT DRIV E YOUR DISCOV ERY. SYNT HET IC CHEMIST RY Confirm the identity and purity of your synthesized product, accurately and quickly, whether using ACQUITY UPLC or UPC 2 systems. Now every synthetic chemist can obtain the correct results quickly and easily without having to send their work to another laboratory for analysis. The result – confident decisions with every analysis. Typical open access report for a medicinal chemist using the ACQUITY UPLC System. The highlighted area shows how the ACQUITY QDa Detector confirms that the required product (310 Da) has been...

For all your samples For all your separ ations For all your scientist s ACQUIT Y QDa Detector Separating Beyond Question™ For more information, visit w w w.waters.com/separate

Waters Corporation 34 Maple Street Milford, MA 01757 U.S.A. T: 508 478 2000 F: 508 872 1990 www.waters.com Waters, T he Science of W hat’s Possible, ACQUITY, Waters Quality Parts, Alliance, Empower, MassLynx, UPLC, UPC2, XBridge, and XSelect are registered trademarks of Waters Corporation. QDa, Separating Beyond Question, ACQUITY UPC2, AutoPurification, CORTECS, and CSH are trademarks of Waters Corporation. All other trademarks are the property of their respective owners. ©2013 Waters Corporation. Printed in the U.S.A. September 2013 720004632EN TC-IGS