BioTrak Brochure
8Pages

MICROBIAL MONITORING CONTINUOUS & INTERVENTION-FREE THE BIOTRAK® REAL-TIME VIABLE PARTICLE COUNTER UNDERSTANDING, ACCELERATED

INNOVATION FOR A CHANGING INDUSTRY Aseptic manufacturing is changing. Ushered in by technologies such as isolators and singleuse systems, automated processes with limited human interventions are rapidly becoming reality. Regulators and manufacturers alike recognize the improved safety and efficiency of highly-automated, continuous manufacturing. This new paradigm demands in-depth process understanding, tight in-process control testing, and fewer interruptions with minimal operator intervention. After decades of reliable service, traditional microbial monitoring techniques (i.e. growth-based...

REE NSTR + VIABLE PARTICLES + NON-VIABLE PARTICLES + MICROBIAL COLLECTION With over 40 years of particle counting experience, and 20 years of viable particle detection in the defense-and-threat detection field, TSI delivers confidence with the BioTrak Real-Time Viable Particle Counter. Dual-channel, Laser Induced Fluorescence (LIF) technology provides the best viable measurements of any real-time Rapid Microbial Method (RMM) available on the market today. And, with TSI you will be working with a trusted, knowledgeable partner in regulated life-science contamination control markets. 1....

IMPROVE EFFICIENCY APPLICATIONS Continuous Process Monitoring The BioTrak Real-Time Viable Particle Counter is the ideal solution for continuous microbial monitoring in the aseptic manufacturing core. Real-time, interruption-free monitoring unlocks process efficiencies and improves quality control. Seamless integration with TSI’s Facility Monitoring System enables complete EM automation. Routine Environmental Monitoring In Grades C/D (ISO 8), the BioTrak Particle Counter is a single instrument for cleanroom certification and episodic monitoring—providing viable and total particle data, as...

& REDUCE RISK BENEFITS Reduce Operator Interventions By sampling air from within the aseptic core while physically outside that space, there is no need for operators to intervene for microbial monitoring. Reduce Line Stoppages Line stoppages increase risk, require costly mitigation, and can even lead to wasted product. By eliminating interventions, the BioTrak RealTime Viable Particle Counter allows continuous operation during fill and finish. Improve Process Understanding Continuous monitoring reveals where and when microbial excursions occur. Time-resolved data demonstrates continuous...

BETTER DISCRIMINATION DUAL-CHANNEL LASER INDUCED FLUORESCENCE (LIF) FIGURE 1: Single Channel Microorganisms contain fluorescent molecules that produce unique PARTICLE SIZE optical signatures. By measuring the size and fluorescent properties BERMUDA GRASS POLLEN of individual particles, TSI’s BioTrak Real-Time Viable Particle Counter RALSTONIA PICKETTII A single channel of fluorescence makes it very difficult to discriminate viable from non-viable particles. effectively distinguishes viable particles from non-viable particles. At the heart of the BioTrak Viable Particle Counter is our Laser...

BETTER RESULTS SPECIFICITY VIABLE COUNTS IN GRADE A & GRADE C (28.3 L/MIN; 1 SAMPLE/MIN; 35MIN) Viable Counts (cummulative) A viable particle count in the absence of a microorganism is considered a false-positive. In critical environments, such as the aseptic core, false-positives can adversely impact processes. With dual-channel LIF and sophisticated discrimination algorithms, the BioTrak Viable Particle Counter reliably delivers essentially zero viable particle counts in rigorously hygienic spaces such as Grade A / ISO 5. The graph shows actual data from real-world manufacturing spaces....

For over 40 years, TSI has been a recognized leader in accurate particle measurements, In fact, TSI is considered the leader in aerosol and particle instrumentation for many applications, including: filter testing, atmospheric and climate studies, ambient air monitoring, nanoparticle measurements, dust monitoring, respirator fit testing, engine emissions, aerosol research, clean room certification, and bio detection, AeroTrak® Particle Counters - Where Research Meets Reality The AeroTrak® line of particle counters, including handhelds, portables, and remotes, are designed to meet the rigid...