Vanquish Duo UHPLC Systems
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Vanquish Duo UHPLC Systems Separate your productivity from the status quo

Three workflows. Two flow paths. One integrated solution. In today’s challenging research and production environments, companies are being asked to be more productive without increasing spending, or compromising quality. At the same time advancements and innovations are needed to improve operational efficiency and performance. How do you accomplish this? It’s easy with the new Thermo Scientific™ Vanquish™ Duo UHPLC systems built for enhanced productivity. Using the Vanquish Duo UHPLC systems you will gain all the benefits of the Vanquish platform in performance, robustness and ease-of-use...

Vanquish Duo system for Inverse Gradient Vanquish Duo system Vanquish Duo systemfor Tandem LC or LC-MS for Dual LC Improve your return on investment by increasing sample throughput and maximizing detector/mass spectrometer utilization. Run two applications simultaneously on a single instrument, whether they are identical or different analyses, for doubled throughput or deeper sample knowledge. Improve your ability to detect and quantify all compounds in your sample with universal Charged Aerosol Detection, even without standards, and see what you’ve been missing.

Maximize mass spectrometer utilization Gradient separations are commonly used in LC or LC-MS. Column reconditioning, such as washing and re-equilibration, takes time and reduces your overall sample throughput. The Vanquish Duo system for Tandem LC or LC-MS eliminates these limitations and improves productivity by: • Increasing sample throughput without modifying a validated method • Improving return on investment by maximizing the instrument utilization • Reducing column carry over through extended column washing without sacrificing throughput • Simplifying method setup with automatic...

“ ince installing the Tandem LC-MS system we S have doubled our throughput and increased the precision of our data!” D r. Richard Rogers Just Biotherapeutics, Inc. Column A Thermo Scientific™ Acclaim™ VANQUISH™ C18 The Vanquish Duo system for Tandem LC or LC-MS splits the analysis between two pumps and two columns. One pump delivers the analytical gradient while the second pump runs the reconditioning gradient. This configuration allows you to use two identical columns to run your sequence faster without compromising data quality. Column B Thermo Scientific Acclaim VANQUISH C18 Reproducible...

Vanquish Duo System for Dual LC Get doubled throughput or deeper sample knowledge Vanquish Duo for Dual LC enables you to run the same or different methods simultaneously on one instrument, doubling your throughput or deepening your sample knowledge while maximizing your productivity and performance. The unique Vanquish Duo system for Dual LC will: • mprove return on investment by reducing cost per sample I • ncrease sample throughput without changing validated methods I • ncrease capacity without sacrificing bench space I • nalyze the same set of samples with multiple methods reducing A...

“ he instrument offers a fantastic increase in T throughput, either while running the same separation chemistry or most excitingly when running two different separation chemistries, enabling us to generate large amounts of characterization data from the same sample quickly.” Jonathan Bones Dr. National Institute for Bioprocessing Research and Training Run your complementary columns in parallel Right channel 100 injections Sample injected on two complementary columns SCX Charge Variant Analysis Thermo Scientific™ MAbPac™ SCX-10 RS column Left channel 100 injections SEC Protein Aggregate...

See the Vanquish Duo System for Dual LC The Vanquish Duo systems have been built to utilize a wide range of analytical detectors, including mass spectrometry (MS), diode array detection (DAD), charged aerosol detection (CAD), variable wavelength detection (VWD), and fluorescence detection (FLD). 1 Versatile detection capabilities Differing molecular characteristics of your analyte, from small molecules to complex biomolecules, necessitate multiple detector methodologies. Vanquish Duo system for Dual LC can be used with any two detectors out of the broad detector portfolio including MS, DAD,...

Vanquish Duo System for Inverse Gradient Improve your quantification and see what you’ve been missing Vanquish Duo system for Inverse Gradient provides you a uniform response for all detectable analytes with the superior charged aerosol detection (CAD). While isocratic separations can yield a uniform CAD response, some separations require gradient elution. By utilizing a second pump to deliver an inverse gradient, the detector offers: • niform response with CAD under gradient elution conditions U • eliable standard-free quantification of knowns and unknowns R • implifying method setup with...

No extra work needed— automatic gradient conversion Peak Area (pA*min) Chromeleon CDS automatically identifies the Inverse Gradient instrument configuration and starts the dedicated method wizard. The wizard calculates and applies the Inverse Gradient to the second pump in the Vanquish Duo System for Inverse Gradient taking into account all internal volumes giving highest quantification accuracy and maximized ease-of-use. Peak Area (pA*min) Calibration curves for four pharmaceuticals without (top) and with Inverse Gradient compensation (bottom) showing similar response factors for all...

See productivity in a new lightOverview of Vanquish Duo systems Regardless of which Vanquish Duo system is right for your lab, each system will improve your return on investment and help you to succeed with your individual goals. With our additional expertise in application, technical and lab service support we can help to accelerate your journey from sample to knowledge. Flow Path 1 Flow Path 2 Recondi- Recondi- Recondi- Reconditioning tioning tioning tioning Time savingsCompared to single channel LC Benefits Analytical Gradient Analytical Gradient...