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Thermo Fisher Scientific - Industrial & Applied S
Reagent-Free Ion Chromatography

Reagent-Free Ion Chromatography

Product catalog summary

Introduction
Dionex has significantly advanced ion chromatography (IC) since 1998 by introducing Reagent-Free™ IC (RFIC™) systems, which automate eluent generation and regeneration, enhancing ion analysis capabilities and productivity.

RFIC Systems
RFIC-EG systems (ICS-2000 and ICS-3000) automate eluent creation using deionized water, while RFIC-ER systems focus on isocratic separations, using a single 4-L eluent bottle for extended periods. These systems reduce maintenance time and increase productivity.

Advantages of Reagent-Free Systems
RFIC systems save time, labor, and costs by eliminating manual eluent preparation errors, improving reproducibility, and reducing the need for equilibration and calibration. They simplify IC operations, making them user-friendly and consistent across different operators and laboratories.

Eluent Generation and Regeneration Benefits
Eluent generators produce high-purity IC eluents, enhancing sensitivity, resolution, and reproducibility. Eluent regeneration uses electrolytic suppression to recycle eluents, reducing waste and maintenance, supporting continuous operation without recalibration.

Eluent Generation Technology
The EluGen® cartridge is central to RFIC-EG systems, producing various eluents for cation and anion exchange applications with precise control over concentration and flow rate.

Advanced Components
Technologies like self-regenerating suppressors and continuously regenerated trap columns improve consistency and reduce labor. Carbonate removal devices minimize interference, enhancing detection limits.

Applications in Water Analysis
RFIC systems are suitable for a wide range of water analyses, including drinking, waste, and groundwater, complying with EPA Methods 300.0 and 300.1. They offer flexibility and accuracy for regulatory compliance.

Column Performance and Detection
The IonPac AS19 and AS22 columns meet EPA standards for detecting oxyhalides in drinking water. Two-dimensional IC is used for bromate analysis, achieving a detection limit of 0.036 µg/L.

Food and Pharmaceuticals
RFIC-EG systems are used for determining benzoate in food products and analyzing cations in high sodium matrices, as well as phosphate and citrate in pharmaceuticals.

Software and System Control
Chromeleon software provides seamless control of RFIC systems, allowing for easy setup and execution of complex concentration gradients, enhancing precision and efficiency.

Conclusion
RFIC systems offer significant improvements in IC productivity, accuracy, and ease of use, reducing manual labor, operational costs, and environmental impact, making them a superior choice for modern laboratories.

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