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HCubeAdvance
HCubeAdvance
The H-Cube® Advance is an enhanced version of the H-Cube® Pro, designed for safe and efficient hydrogenations in laboratory settings. It features advanced functions, a modern user interface, and improved capabilities to facilitate synthetic work.
Product Overview
The H-Cube® Advance maintains the core functions of its predecessor while introducing several improvements:
- Built-in Mass Flow Controller (MFC) for precise hydrogen dosing and external gas treatment.
- User-friendly interface with ergonomic design.
- High hydrogen purity of 99.9%.
- Compatibility with THS ReAction software.
Main Components
The system includes a new generation water electrolysis cell, an external gas inlet, an external water reservoir, and a water purifier cartridge. It supports CatCarts® of various sizes and features an in-line see-through quartz tube for visualizing gas-liquid flow.
Features
The H-Cube® Advance offers both automated and manual modes, allowing for flexible operation. It is compatible with THS HPLC and Knauer pumps and can be remotely controlled via RS-232 and ThalesNano CAN bus.
How It Works
The device is primarily used for hydrogenation and catalyst screening. Reactants are introduced via an HPLC pump, mixed with generated hydrogen, and passed through a catalyst cartridge. The resulting mixture is collected in a flask, with solvent evaporation as the primary work-up.
Chemistry Examples
The H-Cube® Advance is suitable for various chemical reactions, including nitro and nitrile group reductions, double/triple bond reductions, aromatic ring saturations, deprotections, and cross-couplings.
Technical Specifications
- Solvent and reagent flow rate: 0.001-10 mL/min
- Internal H2 gas flow rate: 1-70 NmL/min
- Pressure range: Atmospheric to 100 bar
- Reactor temperature range: 5 – 150 °C (41 – 302 °F)
- Dimensions: 330 x 320 x 330 mm (without display)
- Display size: 11.6”
- Weight: 18 kg
- Mains range: 110 – 240 V AC, 50/60 Hz, 500 W
Contact Information
ThalesNano Inc. is based in Budapest, Hungary, with a US office in Hatboro, PA. For more information, visit their website or social media pages.
Catalog excerpts
H-CUBE® ADVANCE The new H-Cube® Advance is based on the well-known ThalesNano H-Cube® Pro. This compact, bench-top flow reactor, now has more advanced functions, a modern user interface, and many more enhanced features to help the user facilitate synthetic work in laboratories.
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MAIN COMPONENTS CHEMISTRY EXAMPLES PRODUCT OVERVIEW The H-Cube® Advance is an upgraded version of the original H-Cube® Pro, which, in addition to maintaining the basic functions of the original system, contains a number of improvements: — Built-in MFC for the precise dosing of the produced hydrogen or the treatment of the external gases — User-friendly interface, ergonomic design — 3.0 (99.9%) produced hydrogen purity — Compatibility with the THS ReAction software
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H-CUBE® ADVANCE HOW DOES IT WORK? The H-Cube® Advance is mainly used for hydrogenation of many different starting material types, as well as catalyst screening. Additional supplied equipment, such as the HPLC pump, is used to introduce the reactant into the device, where the solution of reactant is mixed with the in-situ on-demand generated hydrogen. The pre-heated mixture is then transferred to a disposable catalyst cartridge (CatCart®) which is preloaded with the required solid catalyst. The mixture is then passed through the solid phase and then collected in a flask. In most reactions the...
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Solvent and reagent flow rate range For more information, please visit www.thalesnano.com Zahony utca 7. | H-1031 Budapest | Hungary Email: [email protected] 50 S. Penn St. Suite B-2 Hatboro PA. 19040 USA E-mail: [email protected]
Open the catalog to page 4All THALESNANO Inc. catalogs and technical brochures
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