H-Cube-Pro

H-Cube-Pro

H-Cube-Pro

Product catalog summary
Product Overview
The H-Cube Pro™ is a cutting-edge instrument for hydrogenation in flow chemistry, allowing safe operations at high pressures without the need for solid catalyst handling or hydrogen gas cylinders. It offers a broad temperature range and adjustable hydrogen levels for selective transformations. Key features include high throughput hydrogen production, active cooling, and a user-friendly graphical interface for real-time monitoring and data logging.

How It Works
The system operates by hydrogenating a continuous flow of reactant, introduced via an HPLC pump. The reactant solution mixes with in-situ generated hydrogen and passes through a preloaded catalyst cartridge (CatCart®), where the reaction occurs. The product is collected in a flask, with solvent evaporation as the primary work-up step.

Chemistry Example: Aromatic Ring Saturation
An example reaction involves the saturation of an aromatic ring using Pd/C as a catalyst under varying conditions of pressure and temperature, demonstrating the system's versatility.

Features
  • Hydrogenation without Cylinders: Generates high-purity hydrogen from water, eliminating gas storage needs.
  • No Catalyst Filtration: CatCart® technology removes the need for catalyst filtration, allowing safe use of pyrophoric catalysts.
  • Higher Throughput and Control: Supports up to 2.0 M concentration and 1mL/min flow rate with adjustable hydrogen production.
  • Touch Screen: Controls all operational steps and parameters, with real-time monitoring and a timer function.
  • Wider Temperature Range: Operates from 10–150 °C for greater selectivity and reaction capability.
  • Intelligent Software: Offers real-time parameter tracking, data export, and automated reaction duration settings.
  • Greater Chemistry Capability: Compatible with additional modules for expanded reaction types.

Technical Parameters
  • Flow rate: 0.3–3 mL/min
  • Temperature: 10–150 °C
  • Pressure: Atmospheric to 100 bar
  • Hydrogen production: 0–60 mL/min
  • Water reservoir: 300 mL
  • Dimensions: 400 mm x 370 mm x 510 mm
  • Weight: 23 kg
  • Voltage: 115–230 VAC
  • Frequency: 47–63 Hz

Additional Components
  • Product Collector: Collects reaction mixture for quick analytical sampling.
  • CatCart®: Sealed catalyst cartridges for efficient and safe reactions, available in two sizes for different substrate quantities.

For more information, visit www.thalesnano.com.
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Catalog excerpts

H-Cube-Pro-1

Be Professional at Hydrogenation and Flow Chemistry

 Open the catalog to page 1
H-Cube-Pro-2

PRODUCT OVERVIEW The H-Cube Pro™ is the new standard for hydrogenation. This instrument enables safe hydrogenation in flow at high pres sures. Quick reactions can be performed without solid catalyst handling or H 2 gas cylinders. The H-Cube Pro™ provides a wide temperature range and the ability to adjust the amount of H 2 helps to solve selective transformations. The H-Cube Pro™ offers great hydrogen production for high throughput, wider temperature capability including active cooling for more selective reactions, and a graphical interface with real time reaction monitoring/data logging and method...

 Open the catalog to page 2
H-Cube-Pro-3

Hydrogenation without cylinders The H-Cube Pro™ contains two electrolytic cells that generate up to 60 mL/min and 100 bar reaction pressure of high-purity hydro gen from water, eliminating the need for gas storage. Temperature may now be varied from 10–150 °C offering greater selectivity at lower temperatures and the ability to perform more difficult reactions at higher temperatures. Intelligent Software Owing to the catalyst cartidge (CatCart ® ) technology catalyst filtration is completely eliminated from the process. The mix ture of starting material and hydrogen enters through filters into...

 Open the catalog to page 3
H-Cube-Pro-4

ThalesNano’s CatCarts® contain sealed heterogenous catalysts, which can be used in hydrogenation and other heterogeneously catalyzed reactions. Exposure to the catalyst is limited by removing the need for filtration, while the cartridges are easy to install and replace. In the CatCarts®, the ratio of catalyst to hydrogen and substrate is significantly increased, which results in faster reaction rates. CatCarts® come in two standard sizes (30, 70 mm). The smaller CatCarts® are used typically to reduce up to 1 g of substrate, while the longer CatCarts® can be reduce over 10 g of material in a day...

 Open the catalog to page 4

All THALESNANO Inc. catalogs and technical brochures

  1. HCubeAdvance

    4  Pages

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.
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