CONTINUOUS FLOW HYDROGENATION REACTOR WITH IMPROVED CHEMICAL RESISTANCE FOR ADVANCED CHEMISTRY The H-Cube® Pro Hastelloy is designed to extend the available chemical space of its renowned counterpart, the classic stainless steel H-Cube® Pro. The whole liquid path of the system is made from Hastelloy C to improve chemical resistance. By this, working with corrosive reagents becomes as easy as any other continuous flow hydrogenation reaction with the H-Cube® product family. • Hastelloy C pump head. • Hastelloy C CatCart® columns with a wide range of heterogeneous catalysts. • No need for hydrogen cylinders, as hydrogen is generated on-demand by the system from water. • Wide temperature range (10-150°C). • Wide pressure range (from atmospheric pressure to 100 bar). • No catalyst handling with pre-filled CatCarts®. • High throughput. • Great reaction control. • Mineral acids and bases. • Strong oxidizers (such as ferric and cupric chlorides). • Nitric, formic and acetic acids, acetic anhydride. • Sea water and brine solutions. • Hypochlorite and chlorine dioxide solutions. • Hydrogen is generated by the electrolysis of water inside the system. • The microHPLC pump delivers pure solvent into the system, where it is mixed with hydrogen using a mixer valve. • The gas-liquid mixture passes through the reaction zone while the system sets the selected parameters (pressure, temperature, and flow rate). • When the desired parameters are achieved and the system becomes stable, the input can be changed from the solvent to the solution of the reactants.

• The reaction mixture passes through a packed column containing solid catalyst (CatCart®), where the reaction takes place. The product leaves the column, but the catalyst stays in the column. • The product is collected in the collection vial. • The reaction scale can range from milligrams to grams. 50 S. Penn St. Suite B-2 Hatboro PA. 19040 USA E-mail: [email protected] For more information, please visit www.thalesnano.com Linkedin: /company/thalesnano-inc-Twitter: /thales_nano Instagram: /thalesnano_inc/ Facebook: /ThalesNano/ Zahony utca 7. | H-1031 Budapest | Hungary Email: [email protected]...