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LyoSuite

LyoSuite

LyoSuite

Product catalog summary
Introduction
Telstar has developed LyoSuite™, an advanced control system for freeze-drying that combines industrial PLC control with a SCADA package, offering a robust and user-friendly framework. The system integrates advanced process monitoring tools, including the patented Dynamic Parameters Estimator (DPE).
Challenges in Freeze-Drying
In laboratory settings, sensors like thermocouples are used to monitor critical parameters. However, in production environments, sensor placement is challenging due to safety, quality, and automation constraints. Additionally, sensors can affect the representativeness of small product volumes.
Dynamic Parameters Estimator (DPE)
DPE addresses these challenges by providing non-invasive monitoring through mathematical modeling. It predicts system states dynamically, eliminating the need for product-intrusive sensors. DPE offers several advantages:
  • No need for sensors in the product.
  • Tracks average batch parameters.
  • Continuously monitors the primary drying process and identifies its endpoint.
  • Applicable to both vials and bulk drying.
  • Supports process scale-up through plant characterization.
  • Enhances process understanding, reducing development time.
Parameters Monitored by DPE
DPE can monitor and record several parameters without product sensors, including:
  • Temperature at the sublimation interface.
  • Sublimation mass flow rate.
  • Primary drying endpoint.
  • Mass transfer coefficient.
  • Heat transfer coefficient.
Conclusion
All Telstar freeze-dryers can integrate DPE, providing a comprehensive solution for advanced freeze-drying process control and monitoring.
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Catalog excerpts

LyoSuite-2

Combined Control Technologies Telstar has extended the concept in control systems for freeze drying combination of technologies which provides robustness and advanced parametric monitoring within a user-friendly LyoSuite™ combines the proven robustness of industrial PLC control with the security of a widely available SCADA package and integrates a suite of tools for advanced process monitoring. At the heart of the system is the patented DPE (Dynamic Parameters Estimator). In the laboratory scientists rely on sensors for measurement of critical product parameters, such as thermocouple for monitoring...

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