Combj/%^y^+ Purlon The Comb'iFlash Rf4" Purlon takes the guesswork out of your purification routine with mass directed purification. Simply instruct the Flash system to collect only those peaks matching the mass of your target compound. Eliminate the need for further analysis. Save time in post purification processing. As with all other CombiFlash models, Teledyne Isco's intuitive PeakTrak® software lets you access all the commands you need from a single touchscreen. Key features include: A Real-time method editing and control A Real time and post run mass spectral data Verify Before You Purify The method development screen facilitates confirmation of the detectable ions of your product, and helps you identify and set appropriate detection parameters prior to the purification process. Standard Features A Flow rates to 200 mL/min at pressures up to A Compatible with column sizes from 4 to 330 A Mass range from 50 to 1200 Dal ton with 1 Dalton resolution A Use with your choice of ELSD, UV, or UV- A Real-time and post-run MS and UV spectral Maximum Intensity - Inject sample to reset Current Intensity SPECTRUM NAME

Table 1: Specifications Flow Rate Range Pressure Limit Variable UV 200 - 400 nm standard. Variable UV-Vis 200 - 800 nm option ELSD Detection Option that can be combined with either UV or UV-Vis 50 – 1200 Dalton, 1 Dalton Resolution Electrospray Ionization (ESI) or optional Atmospheric Pressure Chemical Ionization (APCI) Mass Spectrometry Detection Positive or Negative Ionization Mode SIM Sensitivity Binary gradient with any two of four solvents; A third solvent can be used to add modifier at a fixed percentage. Programmable Gradients Linear, step, isocratic Sample Injection User Interface Fraction...