AUTOMATED CHROMATOGRAPHY SYSTEMS TELEDYNE ISCO

CombiFlash® EZ Prep built on a strong history of chromatography innovations The CombiFlash EZ Prep system is the latest innovation from Teledyne Isco. Nearly 60 years ago, founder Dr. Allington recognized a need for fraction collection to automate preparative liquid chromatography. He developed a fraction collector which is commonly used in chromatography laboratories worldwide. The company continues its emphasis on innovations resulting in a number of patents and products, especially for the laboratory scale preparative market. Early Innovations Early innovations include developing the first...

Start a separation in seconds with our PeakTrak® software. Select a column to load default run, load your sample, and press play. The color-coded screen tells you if the system is in Flash or Prep HPLC mode. You can easily change parameters during the run. Error-free separation with active level sensing. Never run out of solvents, overflow the waste container, or damage Prep HPLC columns. Achieve greatest purity with Prep HPLC capacity. 3500 psi pressure and 200 mL/min binary gradient allow you to run diverse types of Flash and Prep HPLC columns. Save time by running any Prep HPLC column faster...

Flash + Prep HPLC in one system Intuitive PeakTrak® software Small footprint Supports widest column range Active error prevention meets simplicity. The CombiFlash EZ Prep system from Teledyne Isco is a dual function purification system that enables the user to perform both Flash and Preparative (Prep) purifications on the same instrument. Eliminating the need for two separate systems, the EZ Prep system provides the flexibility to seamlessly switch between Flash and Prep HPLC modes without compromising performance. The intuitive user interface of the PeakTrak software minimizes any learning curve,...

Simplify your separation in 3 easy steps. Load a RediSep® column or select the installed Prep HPLC column. PeakTrak® automatically loads a suitable method, ensures you have sufficient solvent available, and flushes the plumbing to switch between Flash and Prep HPLC. Don’t worry about the collection rack; the EZ Prep system recognizes mixed rack sizes and adjusts accordingly. Load your sample. A wide variety of sample loading options allow you to load your compound onto the column for the best separation. Press play. That’s it. If needed, you can edit any parameter “on the fly

Combine Flash and Prep HPLC functionality in only 17" The CombiFlash® EZ Prep purification system is the slimmest of its away from your purification run with confidence. The system will kind, enabling you to fit a Flash and Prep HPLC in a space similar to not run out of solvent before the separation is complete, overflow an analytical HPLC . Additionally, you can increase system flexibility the waste reservoir, or damage valuable Prep HPLC columns. With Teledyne Isco’s patented active level sensing, you can walk with an Evaporative Light Scattering Detector (ELSD) with no increase in size. You...

Best-in-class fraction collection prevents sample loss and solvent spills Simple control options to meet your specific needs Teledyne Isco’s best-in-class RFID-encoded collection racks ensure As with all CombiFlash systems, the EZ Prep saves you time and proper loading every time; preventing errors, solvent spills and increases separation success. An intuitive touch screen display sample loss. When the collection rack is inserted in the EZ Prep provides fast access and virtually eliminates errors, as users select system, PeakTrak identifies tube size and sets the appropriate from clearly defined...

High-resolution purification for a wide range of applications The CombiFlash EZ Prep can be used in a variety of applications, including organic synthesis, drug discovery, natural products, food additives, dyes, small molecules, peptides, agrochemicals, inorganic ligands, and other research applications. PEPTIDES Peptides The EZ Prep with RediSep Prep C4 column separated these peptides to 98% purity based on small differences in their structures. Although both peptides have the same molecular weight, the PurIon mass spectra fragmentation patterns show the compounds are different. Carbohydrates...

your specific needs You can always meet your purification needs with the CombiFlash family of products. Teledyne Isco offers a variety of configurations to best detect your compounds: UV, UV-Vis, (both include Spectra and All Wavelength), ELSDand mass-directed purification. The newest member, the affordable and versatile EZ Prep system, offers multiple detection options and a wide range of columns. For example, start with a UV or UV-Vis detector, then add an ELSD to detect non-chromophoric compounds as the need arises. Or, combine with the CombiFlash9 Purlon mass spectrometer module to obtain...

Industry Leader The industry leading CombiFlash Rf+ with PeakTrak® software increases productivity whether you’re purifying synthetic compounds, natural products, or peptides. With flow rates up to 200 mL/min at 200 psi (13.8 bar), the CombiFlash Rf+ is capable of normal and reverse phase purifications from a few milligrams up to over 30 g. Save valuable bench space with the smallest footprint of any automated Flash system. This network-compatible system saves you time by allowing remote monitoring from almost anywhere. zz Eliminate errors using RFID with RediSep™ columns and racks to load optimal...

Selective Flash Chromatography CombiFlash® Rf+ Purlon takes the guesswork out of your purification routine with mass directed fractionation. Collect only the peaks of interest by selecting target masses for collection. This eliminates the need for further analysis and saves time with fewer fractions, so you can quickly move on to the next step. zz Minimize learning curve with integrated mass spectrometer control Verify ionization and identify possible adducts using the ion finder in method development Save time and solvents with “Terminate on Target” which stops the separation once the peaks...