Automated Flash Chromatography Systems

CombiFlash® Rf+ Family of Purification Systems Flash chromatography is the science of refinement… Teledyne Isco continues to refine its CombiFlash Rf+ Purification systems for simplified ease of use, increased throughput, superior results and the ideal system configuration to meet the laboratories’ needs. Years of experience are behind our safer, smaller, simpler, more capable and more efficient Flash chromatography instruments. Standard features include: • Large fraction capacity for longer runs without changing racks. Fraction capacity is virtually unlimited with rack changes. • Radio Frequency...

Making Flash Chromatography Intuitive While flexibility is at the heart of the CombiFlash Rf family, what is common to all CombiFlash Rf models is our simple, straight forward PeakTrak software: There is no longer a need to build methods where all operating parameters must be detailed before any purification can be run. PeakTrak gets you started with one simple button push. To get started, is as simple as 1,2,3... Prepare your sample Press Play Install a column. The system automatically loads the method. Real Time Spectral Once the purification run starts, all of the run data is at your fingertips...

CombiF/ash® Rf+ PurIon takes the guesswork out of your purification routine with mass directed purification. Simply program the Flash system to collect only those peaks matching the mass of your target compound. This eliminates the need for further analysis and saves time in post-purification processing. Key features include: • Real-time and post-run mass spectral data display. • Robust quadrupole technology. • Quickly switch between the standard ESI probe to APCI for difficult to ionize compounds. • Simplified user interface - no MS expertise required. • A quick self-cleaning function reduces...

Integration of an Evaporative Light Scattering Detector (ELSD) allows detection of compounds with minimal UV absorption such as carbohydrates, steroids, and lipids. The CombiFlash® Rf+ Lumen combines ELSD with either UV or UV-Vis detection to deliver the widest compound detection range in the industry. Key features include: • Conserve valuable hood space - the CombiFlash Rf+ Lumen has an integrated ELSD. • ELSD operating parameters are automatically adjusted to optimize detection based on purification solvents in use. • Detect light sensitive compounds by turning off the UV lamp. ELSD Function...

The CombiF/ash® Rf+ increases productivity whether you're purifying synthetic compounds, natural products, peptides, or polymers. The system is compatible with both normal and reversed phase conditions to meet all your purification needs. With flow rates up to 200 mL/min at pressures of 200 psi (13.8 bar), the CombiF/ash Rf+ is capable of purifications requiring columns up to 330 g in size. With the smallest footprint of any automated Flash chromatography system, the CombiF/ash Rf+ saves valuable bench or hood space. This network-compatible system saves you time by allowing remote monitoring...

The CombiF/ash® Rf 150 delivers normal or reversed phase purifications at a fraction of the cost of preparative HPLC. The system operates at pressures up to 150 psi (10.3 bar). The rugged construction makes this unit a daily workhorse for your demanding schedule. Beginning users will be up and running in a matter of minutes with our intuitive PeakTrak user interface. Don't waste valuable time learning complex software when it could be better spent purifying samples. The system accepts a variety of rack sizes so that purified compounds can be collected in volumes appropriate for the column size...

Making Flash Chromatography Productive Get the ease of use and reliability provided by CombiFlash Rf+ systems and RediSep columns for development scale purification with the CombiFlash Torrent® purification system. The system is designed to adapt to a variety of large-scale purification needs. The CombiFlash Torrent offers flexible sample introduction and Fraction collection options: • Choose between Solid Load Cartridges or liquid loading to introduce samples onto column. • Liquid loading can be either manual or via a sample load pump. • Fraction collection options include a 6-port fraction...

Teledyne Isco offers two lines of Flash Chromatography columns. Both RediSep® Rf and RediSep Rf Gold® offer the following advantages: • High flow rates for fast purification of target compounds. • Reliable, consistent performance from automated precision packing. • Column sizes available for purifying milligrams to hundreds of grams. • RFID technology for automatic set up on compatible instruments (except 4 g silica and 8 g alumina). • Fits all Isco CombiFlash automated organic purification instruments (fits other systems using adapters). • Long shelf life in airtight, re-sealable packages. •...

Choose the CombiFlash® System that Meets Your Needs CombiFlash Torrent Flow Range Maximum Pressure Sample Sizes Column Sizes Gradient Optimization Software RediSep Rf Column Detection Pumping System Dual piston pumps with active valve Ceramic single piston with active valve Dual syringe pumps Dual syringe pumps Dual syringe pumps Variable UV std, UV-Vis optional Variable UV std, UV-Vis optional Variable UV std, UV-Vis optional ELSD, Variable UV std, UV-Vis optional Mass Spectrometer, Variable UV std, UV-Vis and ELSD optional Spectral Display External Detector Input Standard through Fraction Collector...

1 - Wavelength user selectable from 200 - 400 nm 2 - Wavelength user selectable from 200 - 800 nm 3 - Standard options include one set of two collection racks and a 25 g Adjustable Solid Load Cartridge Cap (not applicable to Torrent) For more information about capabilities and benefits of the CombiFlash Instruments, visit our website at www.isco.com. Be sure to download other brochures and application notes made available on our website.