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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS
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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 1

ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 2

Welcome to transformational biomedical technology, engineered to advance tissue growth ElectroForce BioDynamic Series BioDynamic Series Technology Perfusion Bioreactors •3DCulturePro Bioreactor •BioDynamic Bioreactor Single Specimen Mechanical Stimulation Bioreactors •Single Axis •Multi-Axis Multi-Specimen Mechanical Stimulation Bioreactors Other Bioreactor Solutions Accessories Software Support BioDynamic Flow Loop Diagrams Mechanical Stimulation Bioreactor Specifications

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 3

Lowest Controllable Force Multi-Specimen Made for an Incubator The MOST VERSATILE bioreactor system outside of the body Design simplicity provides unmatched performance reproducible test results ElectroForce BioDynamic test instruments provide long-term tissue engineering solutions within a sterile cell culture environment. With a full range of capabilities, choose the configuration that is right for you. From introductory bioreactors to the most versatile mechanical stimulation bioreactors on the market. Apply physiologically-relevant loading conditions Load any Tissue Widest Range of...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 4

ElectroForce BioDynamic Series Blood Vessels Ligaments Bone Stem Cells Cartilage Biomaterials Scaffolds Biocompatible Mechanotransduction Regeneration Differentiation Proliferation Alignment 6 BioDynamic Pulsatile Test Instrument BioDynamic 5110 Axial Test Instrument BioDynamic 5270 Axial/Pulsatile Test Instrument ElectroForce BioDynamic Test Instruments

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 5

BioDynamic Series Technology Industry LEADER in biomedical testing applications for over 20 years Superior chamber architecture ElectroForce bioreactors are engineered so tests can be set up quickly and easily, while still giving users the greatest versatility to run limitless experiments. complete portfolio of tissue culture solutions • Perfusion Bioreactors • Single Specimen Mechanical Stimulation Bioreactors • Multi-Specimen Mechanical Stimulation Bioreactors Scalable configurations meet growing research needs Chambers are optimized to conserve space while allowing for the addition of...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 6

Perfusion Bioreactors 3DCULTUREPRO BIOREACTOR Viable Cells Keep your cells 3D perfusion culture made SIMPLE Non-Viable Cells viable during a multi-month tissue culture experiment so you are measuring the cellular response that actually matters* Set up a test in minutes 6 Week Flow Culture of Smooth Muscle Cells • Easy to use, tool-less chamber design • Integrated media reservoir • Portable and compact Adaptable design • Includes fixtures for a variety of sample types • Can be positioned in 3 orientations • Accommodates multiple flow loops * SV Biechler. 2015. Perfusion flow keeps cells...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 7

Perfusion Bioreactors BIODYNAMIC BIOREACTOR All components in contact with fluid are designed to last many autoclave cycles Native Artery Frictionless, rolling seal designed to precisely load a delicate sample Fluid Shear Stress Control Apply fluid shear stress to of the extracellular matrix (ECM) Transparent viewing windows allow you to image your sample during stimulation Flow ports let you choose the flow loop that is right for your test stimulate cellular remodeling Strain Chamber fillers minimize fluid volume and reduce consumable costs Adjustable hollow shafts lock in place so...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 8

Single Specimen Mechanical Stimulation Bioreactors BioDynamic Pulsatile Test Instrument Optimized design gives you the freedom to focus on your research Increase airway strength and promote physiological cellular alignment by applying dynamic circumferential strain* • Perform simultaneous periodic loading experiments with supplemental chambers • Rigid shafts are hollow to accommodate dynamic flow as well as precise loading of stiff samples • Chamber and flow loop can be autoclaved, assembled, and sealed before transferring to the test frame Ultimate Circumferential Tensile Strength SINGLE...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 9

Single Specimen Mechanical Stimulation Bioreactors MULTI-AXIS BioDynamic 5175 Axial/Torsion/Pulsatile Test Instrument* tri-axis stimulation bioreactor system * Axial/Torsion and Axial/Pulsatile configurations also available ElectroForce BioDynamic Test Instruments

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 10

Multi-Specimen Mechanical Stimulation Bioreactors 4 Chamber Axial/Pulsatile Test Instrument Patented flexure design ensures equivalent loading to all samples • Controlled deformation of all samples with a shared actuator • Each chamber has its own force sensor for independent sample characterization Apply periodic tensile loading to increase expression of tenogenic differentiation markers in tissue engineered tendon* A high throughput, yet highly flexible solution • Multiple chambers enable reproducible results with statistical relevance • Individual or shared flow loop options so you can...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 11

Other Bioreactor Solutions Need a system that goes above and beyond tissue engineering? Glylosamino Glycan Synthesis ElectroForce 5500 Test Instrument with Off-Axis Pulsatile Bellows Add BioDynamic chambers to standard load frame products and experience the full breadth of ElectroForce testing capabilities. Cyclic Compression Apply cyclic compression to promote cartilage regeneration* ElectroForce 3200 Test Instrument with BioDynamic Bioreactor 20 ElectroForce Planar Biaxial Test Instrument with Planar Biaxial BioDynamic Bioreactor ElectroForce 5500 Test Instrument with 24-Well Plate...

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ELECTROFORCE BIODYNAMIC TEST INSTRUMENTS - 12

4-Well Platens ElectroForce® BioDynamic test instruments can be outfitted with a variety of specimen fixtures, upgrade options and software modules to make your test yield the most biologically-relevant results. The Most Flexible Control System Available Software Grips and Platens • DMA Grips • Tissue Grips • BioDynamic® Tensile Grips • BioDynamic Compression Platens - Porous (40 pm and 100 pm) - Nonporous • Porous Membrane Platens • 4-Well Nonporous Platens Fixtures and Chambers • Barbed Fittings • 3 and 4 Point Bend Fixture • Multi-Specimen Fixtures • Additional Bioreactor Chambers •...

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