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BROCH-TAM-lV

BROCH-TAM-lV
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BROCH-TAM-lV

Product catalog summary
TAM IV Microcalorimetry System Overview
The TAM IV is a versatile microcalorimeter system designed for measuring heat in various processes. It offers modular configurations and sample handling systems to enhance laboratory productivity.
System Features and Benefits
  • Temperature control from 4 °C to 150 °C.
  • Stable temperature for long-duration experiments.
  • Four independent calorimeter positions.
  • Accessory Interface box for up to eight accessories.
  • Voltage I/O module for interfacing with probes.
TAM IV-48 High-Throughput System
Features up to 48 minicalorimeters for high-throughput measurements, suitable for biological screening and production control.
Temperature Control Technology
  • Oil-based liquid bath system for stability.
  • Electronic thermistors and sensors for regulation.
  • Isothermal, step isothermal, and scanning modes.
Calorimeter Types and Features
  • Nanocalorimeter: High sensitivity for small samples.
  • Microcalorimeter: Suitable for larger samples.
  • Minicalorimeter: Space-saving design for high throughput.
  • Macrocalorimeter: For large volume samples.
  • Precision Solution Calorimeter (SolCal): High precision for dissolution processes.
Battery Cycler Microcalorimeter Solution
Integrates TAM IV and VSP-300 Potentiostat for enhanced battery testing, offering real-time data monitoring and advanced analytics.
Features and Benefits
  • Integrated software for seamless data collection.
  • Real-time data aggregation.
  • Compatibility with various battery types.
  • High throughput for up to 12 battery samples.
  • User-friendly plug-and-play technology.
VSP-300 Potentiostat Specifications
  • Up to 6 channels.
  • 500mA to 10nA, 760fA resolution.
  • +/- 10V control voltage.
  • EIS 10uHz to 7MHz.
Battery Testing Accessories
  • Tools for various battery types.
Sample Handling - Static Ampoules
  • Non-destructive isothermal measurements.
  • Sealed disposable ampoules for high throughput.
Micro Reaction Systems
  • Open ampoules for sample manipulation.
  • Controlled addition and mixing for titration.
Isothermal Titration Calorimetry (ITC)
  • Characterizes molecular interactions and enzyme kinetics.
Perfusion Systems
  • Continuous flow for adsorption and absorption studies.
Vacuum/Pressure Systems
  • Simultaneous heat flow and pressure measurement.
Solution Calorimetry
  • Characterizes heat transfer and dissolution phenomena.
Microcalorimetry and Solution Calorimetry
Designed for long-term dissolution experiments, calculating enthalpy of transfer between polymorphs.
Battery Testing with Calorimetry
Effective for evaluating battery stability and efficiency, offering unmatched sensitivity and stability.
Pharmaceutical Applications
  • Stability Testing: Provides reliable stability data faster than conventional methods.
  • Drug-Excipient Compatibility: Shows heat flow changes due to incompatibility.
  • Amorphicity & Crystallinity: Quantifies amorphicity in solids.
  • Polymorphism: Monitors polymorphic transformations.
  • Hydrate Formation: Studies humidity-dependent hydrate formation.
  • Solubility Determination: Precisely determines solubility.
Stability of Propellants by STANAG 4582
Evaluates propellant stability using calorimetry, applicable for quality control and surveillance testing.
Stability of Sodium Percarbonate
Calorimetric tests show stability of coated versus uncoated samples under humid conditions.
Material Compatibility
Evaluates interactions between sample components, useful for safety screening.
Laundry Product Compatibility
Tests sodium percarbonate stability in detergents, supporting multi-sample testing.
Stability of Propellant under Controlled Humidity
Humidity affects propellant stability, emphasizing the need for dry storage conditions.
Efficiency of Stabilizers
Measures oxidation processes and stabilizer efficiency in polymers.
Battery Charge-Discharge Cycling
Monitors heat exchange during battery charging and discharging.
Battery Open Circuit Discharge
Measures static self-discharge, indicating battery stability.
Isothermal Microcalorimetry in Biological Science
Valuable for studying metabolic activities and interactions in biological systems.
Isothermal Titration Calorimetry
Studies molecular interactions, providing insights into thermodynamics.
Fermentation
Measures heat production during fermentation, ranking additives based on effectiveness.
Microbial Metabolism
Detects microorganisms and evaluates antibiotic susceptibility.
Microorganism Detection
Calorimetric detection is faster and more sensitive than traditional methods.
Apoptosis
Distinguishes between apoptosis and necrosis by detecting metabolic energy bursts.
Cell Growth - Hormone Stimulation
Assesses cell growth and drug effects, capturing early metabolic events.
Overview of Isothermal Microcalorimetry in Drug Assessment
Highlights rapid evaluation of therapeutic drugs through bioassays.
Biocompatibility Testing
Assesses interactions between human granulocytes and polymer materials.
Specifications of Calorimetric Equipment
Details specifications for TAM IV and TAM IV-48 calorimeters.
References and Data Sources
Includes a comprehensive list of references and data sources.
Contact Information
Provides contact details for TA Instruments and Waters Corporation.
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Catalog excerpts

BROCH-TAM-lV-2

TAM IV Microcalorimetry System All chemical, physical and biological processes are associated with a heat production or heat consumption. Conceived over 25 years ago as a Thermal Activity Monitor the fourth generation TAM is the most sensitive, stable and flexible microcalorimeter system in the world for directly measuring this universal heat signal and, therefore, the quantitative thermodynamic and kinetic observation of any process. It is a unique microcalorimeter system that is completely modular and combines the highest heat flow sensitivity with unmatched long term temperature stability...

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BROCH-TAM-lV-4

SENSITIVE, STABLE AND FLEXIBLE microcalorimeter system. It is completely modular and combines the highest heat flow sensitivity with unmatched long-term temperature stability to measure processes that are undetectable by other techniques. The TAM IV- 48 expands the TAM IV capabilities as a high-throughput microcalorimeter system that can be configured to accommodate up to 48 individual calorimeters. The power and flexibility of the TAM IV thermostat, coupled with the available calorimeters and accessories, creates a flexible, powerful analytical platform suitable for any laboratory and offers...

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BROCH-TAM-lV-5

PRECISE TEMPERATURE CONTROL The TAM IV calorimeter system efficiently and accurately controls the set temperature for the thermostat with advanced hardware and electronics. Precise temperature control and unmatched calorimeter sensitivity ensure all measurements being made will have the best stability, signal-to-noise ratio and reproducibility, even for the most challenging applications. TAM IV Thermostat Features & Benefits: • An oil based liquid bath system for a continuously circulated heat sink medium that prevents any thermal event in the room environment from altering the constant Calorimeter...

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BROCH-TAM-lV-6

Temperature Control Features & Benefits: Isothemal: • Classical mode for microcalorimetric measurements • Thermostat is maintained at constant temperature while heat generated or absorbed by the sample is measured • Both short term and long term experiments can be accurately performed with exceptional stability and reliability • Perform multiple isothermal temperature analyses in a single experiment • Identical signal stability and sensitivity is achieved as in conventional isothermal experiments. • Data recorded continuously for detecting temperature-dependent events during Step isothermal:...

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BROCH-TAM-lV-7

TAM IV TEMPERATURE RANGE TECHNOLOGY ACCURATE TEMPERATURE RANGE TAM IV High Efficiency Cooling System The TAM IV is designed for reliable operation at an extended temperature range of 4 °C to 150 °C. The expanded sub-ambient temperature range extends the application capability of the TAM IV to more accurately simulate low temperature conditions and accurately assess Arrhenius kinetics. Features & Benefits: • The TAM IV utilizes proven hardware and electronic controls to ensure stable and reliable operation from 4 °C to 150 °C High efficiency heat sink • User installable dry gas purge system ensures...

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BROCH-TAM-lV-9

The primary TAM IV calorimeters are heat flow calorimeters. All calorimeters are twin type calorimeters, consisting of a sample and a reference and measuring the heat flow difference between the two positions. All installed calorimeters can operate simultaneously and independently • Enables experiment optimization based on - sample volume - absolute sensitivity - addition of external stimuli and complimentary measurements such as humidity, titration, electrical potential, atmospheric pressure, and more • Maximum sensitivity with the Nanocalorimeter and Microcalorimeter featuring user-accessible...

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BROCH-TAM-lV-10

Sample Size Absolute Sensitivity

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BROCH-TAM-lV-11

The Nanocalorimeter and Microcalorimeter employ a user accessible reference and deliver the maximum in heat flow sensitivity. Heat flow measurements on these calorimeters are easily optimized by matching each specific sample condition with an appropriate reference material. The Nanocalorimeter is designed for up to 5 mL samples. The Microcalorimeter will accommodate larger samples and/or provide a larger gas phase above the sample. • Achieves highest sensitivity with inert substance in user accessible reference • Maximum sample flexibility for all static ampoules up to 5 mLs • Compatible with...

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BROCH-TAM-lV-12

• Designed for larger volume samples - accommodates 20 mL static ampoules in glass, stainless steel and Hastelloy • Compatible with 20mL micro reaction systems for • Uniquely designed for the TAM microsolution ampoule applications - Dissolution of very small amounts of solids in various solvents - Dissolution of slowly soluble substances - Heat of dissolution and kinetics of dissolution • Compatible with the 20 mL vacuum/pressure ampoule for simultaneous collection of heat flow and pressure data • Each calorimeter occupies only one of the four positions in the TAM IV thermostat

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BROCH-TAM-lV-13

TAM IV CALORIMETERS WITH FIXED REFERENCE Sample access tube Minicalorimeters have a permanent reference and are designed to reduce the space occupied in the thermostat to increase sample throughput. An assembly of up to six minicalorimeters is designated as a multicalorimeter which occupies only one of the four calorimeter positions in the TAM IV thermostat. Sample side Minicalorimeter Features & Benefits: • Space saving over-under design allows high throughput calorimetry by maximizing the number of calorimeters that can be used simultaneously Heat sink Heat flow detectors • Permanently mounted...

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BROCH-TAM-lV-14

One of six sample access tubes One of three sample access tubes Multicalorimeter Features & Benefits: • 4 mL multicalorimeter - six 4 mL minicalorimeters • 20 mL multicalorimeter - three 20 mL minicalorimeters • Multicalorimeter assembly occupying one thermostat position increases sample throughput by three- to six-fold • Maximum throughput and experimental design flexibility: - Choice of identical or different reference inserts for each calorimeter Assembly of three 20 ml minicalorimeters

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.
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