1/ Overview of Industrial Freeze Dryers SYSBIOTECH’s comprehensive and flexible range of Industrial freeze dryers is developed for optimized and carefully controlled low temperature vacuum drying of biotechnological and pharmaceutical substances, in order to protect product stability, structure and activity of the dried product. 2/ Two series of Industrial Freeze Dryers The LP series of freeze dryers can be supplied with condenser chamber volumes ranging from 50L to 500L and is especially suitable for Biotechnology and Food applications. The LP-SCM series of freeze dryers covers the same volume range as for the LP series however, with a choice of materials, features and documentation package in compliance with Pharmaceutical Industry requirements and standards. Equipment hardware, software and functional quality meet the following requirements and standards for use in biotechnology and in biopharmaceutical industry: O cGMP (current Good Manufacturing Practice) O FDA (Food and Drug Administration) Q EHEDG (European Hygienic Equipment Design Group) 3/ Features and options: O C-BIO2™ operating and monitoring with touchscreen control O Clean room compliant stainless steel construction O Choice of hydraulic door closures, minimizing LAF requirements O Butterfly shut-off valve O CIP (clean-in-place) and SIP(sterilize-in-place) options O IQ/OQ validation documentation Standard specification for industrial freeze dryers:

ilShin lab-scale and pilot-scale freeze dryers are developed for optimized and carefully controlled low-temperature vacuum drying of biotechnological and pharmaceutical substances, in order to protect product stability, structure and activity of the dried product. Lab-scale Freeze Dryers Table-top TFD and floor-standing FD series of freeze dryers can be supplied with condenser chamber volumes ranging from 3L to 18L and are widely used for biotechnology, food and pharmaceutical applications during process research, development and scale-up operations prior to industrial-scale production. Pilot-scale...