Research and Development Tray Freeze Dryer Specifications Lowest Shelf Temperature Shelf Temperature Control Range Shelf Temperature Control Range Tolerance Shelf Pull-Down from 25°C to -40°C Lowest Condenser Temperature Maximum Condenser Capacity Condenser Surface Area Condenser Pull-Down from 20°C to -45°C Compressor Horsepower (high-stage / low-stage) System Refrigerant (high-stage / low-stage) Vacuum Time to 100 Millitorr Vacuum Rate of Rise (per hour) Volume-Based Leak Rate Lowest System Vacuum Vacuum Level Control Range Vacuum Level Control Temperature Uniformity§ Note: Performance specifications are based on SP test data from clean, dry and empty (CDE) units operating at an ambient room temperature of approximately 20°C. SP recommends an optimum operating range of 16-25°C (60-77°F). Utility Requirements Compressed Air† Ambient Room Temperature Cooling Water (water-cooled units) Unmatched process accuracy and reliability Optional LyoFlux* TDLAS and Tempris* Sophisticated instrumentation set Advanced cycle development and optimization features SMARTTM Freeze Dryer technology Clean room or isolator integrable Solvent package available ControLyo® Controlled Nucleation Technology ready, which allows for adding ControLyo® at any time 4 shelf configuration available Utility Considerations Heat Output Room, Peak (air-cooled units) Heat Output Room, Peak (water-cooled units) ControLyo® Requirements (Optional) Volume to Vent percentage ratio (VV/VR)‡ Note: Vent Volume (VV ) is the product chamber volume multiplied by 10. The volume of a standard SP Hull LyoStar® 4.0 chamber is 0.113 m3 (3.99 ft3). VR is the volume of the room in which the lyophilizer is located. Front View

Research and Development Tray Freeze Dryer Dimensional Data Shelf Configuration Number of Shelves Maximum Weight (estimated) Minimum Clearance on All Sides Note: SP recommends a 60 cm clearance around all sides of the unit for serviceability. If machines are placed side by side, increase the minimum clearance to 1.2 m. Shelf Area Shelf Clearance Refrigerant Information Electrical Requirements Voltage Shelf Clearance with Shelf Latching Safety Class Breaker Amperage Workstation Electrical Requirements Voltage (VAC) Additional Information Construction Vacuum Pump Isolation Valve Refrigerant Type...