IO SINGLE & PARALLEL AUTOCLAVABLE FERMENTERS/ BIOREACTORS LOGO SOLARIS VERTICALE NEW COLORS

IO IO, the smallest scale Solaris platform, offers 200 ml and 1000 ml total volume autoclavable vessel sizes. The system utilizes innovative Leonardo software, capable of managing up to 24 systems in parallel. IO typical applications includes the following: Education & Basic research Scale-up and scale-down studies Process development and optimization IO can be used for: Biopharmaceutical Biofuels Food industry Bioremediation Bioplastic Cosmeceutical Nutraceutical Fast and accurate thermoregulation without water circulation Parallel control up to 24 units

Up to 24 units managed with one HMI with innovative PARALLEL process control LEONARDO: smart controller designed to provide an high level of automated management of the fermentation/cultivation processes Powerful/ Accurate brushless motor, from 1 to 2000 RPM. Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth Modbus Digital sensors LEDA safe sterile sampling system The needle free connector is designed to reduce the risk of contamination during sampling. The sterile combination of a syringe (3-5-1030 ml) and a non return valve...

Modbus Digital sensors Why a digital sensor? USER-FRIENDLY SOFTWARE Digital sensors (including Cell Density products) have been integrated to the Solaris PCS and Leonardo controlling software, giving the user many benefits over traditional analog sensor outputs. Such benefits include a robust communication protocol not susceptible to signal loss, in-software sensor diagnostic information, parallel calibration/batch calibrations and more. Sensor life traceability Reducing background noise Solaris controlling software offers a simply laid out, yet powerful platform for experimental design planning...

SDGMsim & [MMULHIL IO Data sheet Controls Vessel Dimensions for autoclave (with condenser) Height (mm) 280 380 Cell density Digital sensor Mammalian cells in suspension ± 5-104 cells/ml -Fermentation ± 0.05 g/l dry weight Measuring resident in Leonardo 2.0 software Dencytee: Total cell density based on turbidity (10A5 to 10A8 mammalian cells/ml- 0.5 to 100 g/L dry weight) Incyte: Viable cell density based on capacitance (5x10A5to 8x10A8 mammalian cells/ml-5 to 200 g/L dry weight) Sensor Accuracy Control system Option 1 Option 2 FERMENTERS CONNECTED!

SOLARIS BIOTECHNOLOGY srl Via Bachelet, 58 - 46047 Porto Mantovano Mantova - Italy Phone: +39 0376 408760 Fax: +39 0376 385108 Email: [email protected] www.solarisbiotech.com