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LCMS-TQ RX Series

LCMS-TQ RX Series
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LCMS-TQ RX Series

Product catalog summary
Introduction
The LCMS-TQ RX Series by Shimadzu is a line of triple quadrupole liquid chromatograph mass spectrometers designed for high reliability and performance in routine analysis. These instruments are engineered to meet the evolving needs of laboratories with innovative technology and exceptional design, focusing on reducing environmental impact and operating costs.
Key Features
  • Heated ESI Probe: Enhances ionization efficiency for a wide range of compounds using a heat-assisted electrospray ionization probe.
  • Ultrafast Power Supply: Enables rapid switching between positive and negative ionization modes in just 5 milliseconds.
  • CoreSpray Technology: Improves nebulization performance with advanced gas delivery for better heat distribution.
  • UF-Qarray™: Focuses ions over a wide m/z range using overlapping electric fields for enhanced ion transmission.
  • UFsweeper™ Collision Cell: Provides fast and accurate MRM quantitation with high-speed CID for multi-component analysis.
  • Ultrafast Detector: Ensures sensitive and stable signal detection with minimal pause and dwell times.
Technological Innovations
  • Analytical Intelligence: Automates instrument optimization by emulating expert decision-making, enhancing data reliability.
  • PERFORMANCE CONCIERGE™: Simplifies mass spectrometer tuning and maintenance, ensuring optimal performance and maximizing uptime.
  • LabSolutions Connect MRM: Automates MRM optimization for high sensitivity quantitative methods, storing parameters in a database for efficient method development.
Performance and Reliability
The RX Series is designed to deliver high data quality with advanced ion guide and collision cell technologies. It supports simultaneous analysis of multiple analytes with high-speed polarity switching and robust performance, as demonstrated in tests with pesticide residues in black tea matrix.
Conclusion
Shimadzu's LCMS-TQ RX Series offers unmatched capability and reliability for laboratories, with innovative features that enhance productivity and data quality while reducing environmental impact and operational costs.
Specifications and Features
  • UFswitching: Enables high-speed polarity switching in 5 milliseconds, maintaining ion intensity and allowing high data sampling rates across narrow UHPLC peak widths.
  • LabSolutions Connect MRM: Automates MRM optimization for high sensitivity quantitative LC-MS/MS methods, storing optimized parameters in a database to accelerate method development and routine analysis.
  • Peakintelligence for LCMS: An AI-driven peak integration algorithm that requires no user settings, providing consistent peak integration and reducing manual data review time.
  • LabSolutions Insight: A dynamic data review application that supports 'review by exception' to identify outliers and streamline reporting.
Maintenance and Usability
  • Easy Maintenance: The RX Series features user-friendly maintenance with quick replacement of ESI capillary and desolvation line without breaking vacuum, reducing downtime.
  • Ionization Options: Offers flexibility with optional APCI, DUIS™, and DPiMS ionization units, allowing analysis of a wide range of polarities.
Environmental Responsibility
  • Energy Efficiency: The LCMS-TQ RX Series includes an ecology mode that reduces electricity consumption by 31% by shutting down the instrument when idle, contributing to lower operating costs and CO2 emissions.
  • Reduced Waste: Features an oil-free rotary pump to eliminate oil changes and reduce environmental waste.
Applications and Method Packages
The document lists various method packages and MRM libraries available for different types of analyses, such as residual pesticides, veterinary drugs, and water quality analysis, which streamline multi-component analysis and eliminate extensive method development.
Ecology Mode
The LCMS-TQ RX Series includes an ecology mode that monitors system usage and automatically shuts down the instrument when idle, reducing electricity consumption by approximately 31%. This feature, along with powering down peripheral equipment during non-analysis periods, significantly lowers operating costs and CO2 emissions.
Oil-Free Rotary Pump
The introduction of an oil-free rotary pump eliminates the need for oil changes, reduces oil consumption, and minimizes environmental waste.
Environmental Impact
The combination of the PERFORMANCE CONCIERGE and ecology mode reduces solvent and power consumption, contributing to a lower environmental footprint.
Power Consumption Comparison
A graph illustrates the power consumption savings when using the ecology mode, showing a 31% reduction compared to not using the mode.
Usage and Availability
The LCMS-TQ RX Series is intended for research use only and may not be available in all countries. Users are advised to check product availability.
Disclaimer
The document includes a disclaimer regarding the use of trademarks and the accuracy of the information provided, which is subject to change without notice.
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Catalog excerpts

LCMS-TQ RX Series-1

Liquid Chromatograph Mass Spectrometer

 Open the catalog to page 1
LCMS-TQ RX Series-3

LCMS-TQ RX Series Innovative technology, exceptional design and new ways of thinking are part of our engineering DNA delivering solutions for the ever-changing needs of any laboratory. As our scientific and business needs change our engineering design evolves and adapts. The result is the RX Series of triple quadrupole LC-MS instruments designed with unmatched capability, redefined reliability and creating a new standard in actionable data. Designed specifically for routine analysis that requires high reliability Trusted performance even with the changing scientific and business needs of laboratories...

 Open the catalog to page 3
LCMS-TQ RX Series-4

Ultrafast Sensitivity and Performance Reliable Shimadzu's RX Series expands the capability and productivity of triple quadrupole mass spectrometer with performance that can be relied upon. The RX Series has been designed to generate a highly focused ion beam from the ion source to detector bringing together advanced ion guide and collision cell technologies. The result is higher data quality that makes an impact on any LC-MS/MS assay. Heated ESI Probe The RX Series are equipped with a heat-assisted electrospray ionization probe. The resulting highly efficient desolvation process promotes the...

 Open the catalog to page 4
LCMS-TQ RX Series-5

Quadrupole Rods Ultrafast Detector The quadrupole mass filter is the heart of a mass An ultrafast high-voltage power supply enables sensitive spectrometer. Shimadzu manufactures and stable signal detection, with a short pause time, dwell high-performance hyperbolic quadrupoles for time and polarity switching time. idealized ion transmittance and high sensitivity, even at a scanning rate of 30,000 u/s. UF-Lens ™ UF-Qarray ™ Shimadzu’s Patented Qarray ion guide is designed to effectively focus ions over a wide m/z range using multiple overlapping electric fields. The ion guide system integrates...

 Open the catalog to page 5
LCMS-TQ RX Series-6

LCMS-TQ RX Series CoreSpray Technology Reliable CoreSpray Enhanced Ionization Performance CoreSpray, a newly developed gas delivery system, improves performance and uniformity of nebulization with higher flows and better heat transfer. Peak Area Stability in Matrix: 20,000 Continuous Injections CoreSpray technology applied to the repeated analysis of pesticides in black tea matrix resulting in enhanced robustness (%RSD less than 3.5%, 20,000 injections). Data generated without internal standards and without diverting to waste for the initial polar matrix effects. Peak area Injection number

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LCMS-TQ RX Series-7

PERFORMANCE CONCIERGE makes tuning a mass spectrometer easier than ever before. A tuning standard is automatically introduced into the instrument to verify parameters, including mass accuracy, resolution, and signal strength. Based on these checks, tuning may be automatically initiated to ensure optimal performance. Should the criteria not be met, PERFORMANCE CONCIERGE will diagnose the issue and alert the operator of required maintenance and maximize uptime. Analytical Intelligence represents Shimadzu's innovative approach to automated analytical instrument optimization. This concept encompasses...

 Open the catalog to page 7
LCMS-TQ RX Series-8

^Reliable^ #Resjjien^ Responsjbjel Intelligent tools to help your workflow efficiency generating higher productivity and better data quality. Mass spectrometer tuning and checks for mass accuracy, resolution, and intensity can be performed automatically using the System Check function. The tuning standard is automatically injected into the system, and re-tuning can be automatically initiated if required, resulting in consistent data acquisition and laboratory operation without the need of user intervention. Tuning report outputs ensure traceability of instrument status. Optimization of Acquisition...

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LCMS-TQ RX Series-9

Automates MRM optimization to create high sensitivity quantitative LC-MS/MS methods. LabSolutions Connect MRM not only optimizes target component MRM transitions and collision energies but also maximizes the response for on column analysis. All optimized acquisition parameters are stored in a data base helping to accelerate both method development and routine analysis. UFswitching: High Speed Polarity Switching The RX Series triple quadrupole mass spectrometers have unique technology for switching polarity in 5 milliseconds between positive and negative ion modes without affecting The result...

 Open the catalog to page 9
LCMS-TQ RX Series-10

Data Analysis Tools to Help Accelerate Data Processing and Report Meaningful Results Peak Integration Peakintelligence ™ for LCMS Peakintelligence for LCMS is a world-first AI driven peak integration algorithm requiring zero user settings. The impact is dramatic. Peakintelligence for LCMS delivers higher consistency in peak integration and results in higher data quality and with far less time manually reviewing data. Reviewing Data and Reporting Results LabSolutions Insight ™ LabSolutions Insight supports a dynamic quantitative data review landscape with the tools to drive high confidence in...

 Open the catalog to page 10
LCMS-TQ RX Series-11

Peaks with a low S/N ratio Q 355.15>88.15 (+) Data analysis time Peaks not separated from contaminant or isomer peaks PeakIntelligence for LCMS is an AI driven PeakIntelligence for LCMS was applied to the algorithm for component detection and peak analysis of a panel of pesticides in a residue integration without the need for any user screening study highlighting consistent peak parameter. PeakIntelligence for LCMS integration at low S/N or with overlapping processing results in higher consistency in peak integration and reduces the time-consuming impact of manual review to achieve a more accurate,...

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LCMS-TQ RX Series-12

LCMS-TQ RX Series Reliable LCMS - 8 0 60R X The LCMS-8060RX builds on the exceptional sensitivity and UF capabilities of the LCMS-8060NX and adds even more robustness without compromising sensitivity. LCMS - 8 0 50R X Engineered to deliver excellent sensitivity the LCMS-8050RX further extends the performance of the LCMS-8050 to meet the ever-changing needs of any LC-MS/MS laboratory. LCMS - 8 0 4 5R X Designed for rugged, routine LC-MS/MS analysis with the optimal balance of cost, sensitivity and performance now enhanced with greater robustness and easier to use.

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.