Shimadzu's Mass Spectrometry Solutions LCMS Family ULTFtjfX FAST MASS SF>FCTFtOMF TFTK

Shimadzu’s Unique Technologies for Extending High-Speed Capabilities Have Established a New Benchmark in Mass Spectrometry Being a provider of mass spectrometry devices since 1970, and with the spirit of meticulous engineering, Shimadzu has continued to improve the ion optics, collision cell design and data acquisition systems. Recently, breakthrough technologies such as UF-Lens™, UF-Qarray™ and UFsweeper ™ have resulted in dramatic improvement of acquisition speed, which brought about a revolutionary change in the way multi-analyte quantitation can be run. The term Ultra-Fast Mass Spectrometry...

Triple Quadrupole LCMS The simplest and most common form of a tandem MS (MS/MS) system is the triple quadrupole mass spectrometer (TQMS). It consists of three quadrupoles arranged in series with the first and third quadrupole acting as MS1 and MS2 filters, respectively, and collision-induced dissociation (CID) taking place in the second quadrupole. Shown in the schematic below is the measurement mode termed multiple reaction monitoring (MRM), which can achieve the highest sensitivity among all instrument types. With selectivity, specificity and sensitivity with minimal background, TQMS is an...

LCMS-8060 Changes Everything The LCMS-8060 is the cornerstone model in the UFMS series. It delivers world-class sensitivity and excellent quantitation performance. Sensitivity is maintained even in the most difficult matrices, suitable for drug discovery, manufacturing, clinical research, food safety, environmental, or drugs-of-abuse analysis. High-throughput detection of a proteotypic peptide of C-Reactive Protein using conventional flow rate. 100 Synthetic peptide AFVFPK in neat solution Tryptic peptide from CRP in pooled human plasma LCMS-8050 Speed and Sensitivity Beyond Comparison The LCMS-8050...

LCMS-8045Best-in-class Sensitivity The LCMS-8045 was designed to be robust and indeed it is the workhorse machine for the most routine applications of food safety and forensic toxicology. The heated ESI probe, high-temperature heat block, heated desolvation line, drying gas and focusing optics all act to minimize contamination for the best-in-class sensitivity achieved. It withstands long periods of continuous operation in laboratories in demand of reliable data. MRM chromatogram of nitrofuran metabolites spiked in fish (0.5 ng/mL) The LCMS-8040 is the long-proven UFMS providing acquisition speed...

Software and Solution Packages for TQMS LabSolutions Connect™ The Gateway to Better Results and Workflow Optimization of MRM parameters is a mandatory process to achieve high sensitivity in analyses, and it can be a complicated workflow if a laboratory works with multitude of new compounds or projects. LabSolutions Connect provides the automation platform with a sophisticated algorithm to standardize the process and to manage the results in a compound database. It also assists LCMS method creation using the information stored in the database and subsequent batch analysis. 1. Reviewing optimization...

This optional license addendum to LabSolutions Insight is fully recommended for scientists undergoing known-unknown screening for forensic toxicology, veterinary drugs and pesticides. The Library Screening option adds the library search capability to further increase the identification confidence of the quantitative signal, provided that the data contains either product ion scan or multitude of MRM transitions (MRM spectrum mode). Shimadzu offers a wide variety of method packages containing LC separation conditions, retention times and validated MRM parameters for large numbers of compounds....

Single Quadrupole LCMS Speed is Power – Seeing is Believing This ultra-fast single quadrupole MS serves as the ideal detector for HPLC or UHPLC for quick assessment of impurities and accelerating target purification. Like other UFMS families, the LCMS-2020 is fast, robust and sensitive. Mass chromatogram of PEG-400 2500000 2250000 2000000 1750000 1500000 1250000 1000000 750000 500000 The optional software Open Solution™ Purification facilitates complex purification processes by intuitive user interface and extensive automation of analysis, fractionation and purity assessment. 1. Analysis • Automatically...

Shimadzu's quadrupole time-of-flight (Q-TOF) LCMS uses a hybrid of technologies. Ions generated at the ion source are first focused into a 'beam' and transmitted through the quadrupole, using the proven UFMS technologies such as UF-Lens and UFsweeper collision cell. On the other end, the new TOF technology analyzes the ions in 'pulses', measuring the time taken for the ions to travel through a high vacuum chamber (flight tube) to resolve and determine their masses. High mass resolution and mass measurement accuracy achieved in this way are the key features of Q-TOF LCMS. It is used extensively...

Software and Solution Packages for Q-TOF LCMS LabSolutions Insight Explore™ Software for Both Qualitative and Quantitative Analysis LabSolutions Insight Explore offers an intuitive and full-featured quantitative environment with significant qualitative enhancements. A sophisticated peak detection algorithm detects chromatographic features based on their accurate mass. Resulting peak displays enable ranked formula prediction with theoretical spectral matching. With this integrated platform, scientists can leverage on the sensitivity, mass measurement accuracy and acquisition speed of the LCMS-9030...

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LCMS Family Brochure UF-Lens, UF-Qarray, UFsweeper, UFMS, IonFocus, LabSolutions Connect, LabSolutions Insight, LabSolutions, Open Solution, UF-FlightTube, LabSolutions Insight Explore, DUIS and DPiMS are trademarks of Shimadzu Corporation. For Research Use Only. Not for use in diagnostic procedures. This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country. Company names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation,...