UHPLC Method Scouting System Nexera
12Pages

Ultra High Performance Liquid Chromatograph Method Scouting System Nexera Method Scouting

Maximizing Efficiency for Method Development The Nexera Method Scouting System design is based on the Nexera next-generation ultra high performance liquid chromatograph. It uses special Method Scouting Solution control software and a robust, high-pressure resistant column switching system to switch mobile phases and columns automatically, achieving a quick and accurate method scouting workflow. As a result, this system provides strong support for efficient HPLC method development. Fully Automated Method Scouting A Variety of Mobile Phase and Column Combinations… Mobile phase (Aqueous)...

The solution from Shimadzu to troublesome method development Nexera M ethod Sc outing Special Method Scouting Software

Enhancing Method Development Efficiency by Nexera Method Scouting In a typical method scouting procedure, data is collected using a capable of automatically investigating up to 96 combinations of number of mobile phase and column combinations. Analyzers mobile phases and columns, without such time restrictions, thereby switching manually between these combinations are limited by the significantly improving method development productivity. number of work hours in a single day, making it impossible to perform method scouting efficiently. The Nexera Method Scouting System is UHPL pical Typical...

oper night Method scouting performed by UHPLC, followed by transfer to conventional conditions Conventional columns If the transfer program is used, the ultra-high speed conditions obtained with the Nexera Method Scouting System can be easily transferred to conventional conditions. Furthermore, this software can be used to investigate the robustness of methods under conventional conditions. The Nexera Method Scouting System is an all-round LC that enables the collection of ultra-high speed UHPLC columns data and conventional data using a single system. Shim-pack XR-ODS (50 mmL. × 3 mmI.D.,...

Method Scouting Workflow With Method Scouting Solution, just set the required conditions to its browser functions, as well as CLASS-Agent and Agent Report, create a scouting batch automatically. This saves time with respect the numerous chromatograms obtained from method scouting can to method creation, management, and batch creation, issues in be quickly evaluated, thereby enhancing method development method development to date. In addition, by combining this system with the Shimadzu’s HPLC workstation, LabSolutions, and utilizing Startup of equipment and special software Analysis...

Nexera Method Scouting Software Method Scouting Solution Easy selection of mobile phases and columns from libraries Simple gradient pattern settings automatically) Automatic generation of scouting batch schedules Comparison and evaluation of chromatograms Method establishment Method Scouting

Method Scouting Solution: Supporting Fast, Secure Operation Method scouting results are important data for determining analysis conditions, so obtaining highly reliable data is essential. Method Scouting Solution provides the data required for analysis via a graphical user interface, as well as automated controls conforming to laboratory operations configured in the system settings, thereby providing data reliably. Achieving automation of laboratory operations Mobile phase purge conditions and equilibration when automatically switching mobile phases and columns are key issues in method...

Graphical data provided to support reliable analysis Method scouting uses a variety of mobile phase and column combinations. Method Scouting Solution calculates the required amounts of these mobile phases and samples in advance, and provides this data to avoid shortages. Furthermore, upper pressure limits are automatically controlled based on column pressure resistance data registered in the column database, thereby avoiding degradation of precious columns. In addition, the system provides estimates of completion time, with consideration to the time required between analyses for processes...

Nexera System: Providing Highly Reliable Data The Nexera Method Scouting System is based on the Nexera UHPLC, ultra-high speed analysis featuring stable solvent delivery at ultra-high which has an its established reputation for ultra-high speed analysis. pressures, excellent injection repeatability from low injection As a result, highly reliable method scouting results are provided using quantities, and ultra-low carryover. Basic configuration of the Nexera Method Scouting System The Nexera Method Scouting System achieves stable data acquisition manifold. In addition, with auto-purging,...

Sample Application P e ak t r acking v ia interlink with L C / MS An LC/MS can be used as the Nexera Method Scouting System detector. Mass spectral data from LC/MS systems support peak component specification. As a result, peaks can be identified without re-analyzing individual components. Scouting for preparative conditions The Nexera Method Scouting System is also effective for the selection of columns and mobile phases in the investigation of preparative conditions. Results scouted with these conditions can then be transferred to the Prominence preparative system, enabling the...

materials. Download them from the following URL, or contact our sales department or your local Shimadzu representative. | Technical Report Vol. 33. Improved R&D Efficiency Through Speedier Method Development (1) http://www.shimadzu.com/an/literature/hplc/jpl211001.html | Technical Report Vol. 34. Improved R&D Efficiency Through Speedier Method Development (2) http://www.shimadzu.com/an/literature/hplc/jpl211002.html Company names, product/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation or its affiliates, whether or not they are used...