Gas Chromatograph Mass Spectrometer GCMS-TQ8040
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Gas Chromatograph Mass Spectrometer

Smart Technologies Smart Productivity, Smart Operation, Smart Performance Finally, a triple quadrupole GCMS Smart enough for everyday use in your laboratory.

The Shimadzu GCMS-TQ8040 is the first triple quadrupole with Smart Productivity for high efficiency sample throughput, Smart Operation for quick and easy method development, and Smart Performance for low detection limits and Scan/MRM. These three smart technologies contribute to Smart MRM, and provide the most accurate, cost-effective, and easy-to-use triple quadrupole GCMS you have ever imagined. Simultaneous multi-component analysis is now possible for hundreds of target compounds, dramatically improving productivity. Smart MRM produces GC-MS/MS methods with up to 32,768 transitions in a...

GC-MS/MS analysis requires multiple settings that can be confusing to the average operator. With Smart MRM, the GCMS-TQ8040 software sets the analytical conditions automatically, making method development painless, fast, and easy. The exceptionally efficient ion source and collision cell provide low detection limits. High-speed scanning control (Advanced Scanning Speed Protocol, or ASSP） and simultaneous Scan/MRM analysis mode provide high-quality library searchable fragmentation spectra, and accurate low-level quantitative data in a single analysis. P. 12 to Smart Performance Gas...

Innovative Technologies that Improve Accuracy and Throughput UFMS in the Multiple Reaction Mode can acquire over 800 transitions per second and over 32,000 transitions in a single analysis. The Smart MRM technology automatically adjusts the analytical dwell time for each transition, only acquiring data during peak elution, to fully optimize sensitivity. For example, analysis of more than 400 pesticides that used to require two or three methods can now be accomplished in a single acquisition method created by Smart MRM, significantly increasing laboratory throughput. The UFMS technology...

Reduce Analysis Costs and Minimize Downtime If simultaneous, multi-component analysis can be performed in 1/2 to 1/3 the time of existing systems, then two to three times the number of samples can be analyzed in the same period of time, and return on investment is improved. In addition, the frequency of maintenance, such as replacing glass liners and columns, is reduced, thereby minimizing downtime. z Twin Line MS System Eliminates the Need to Vent the MS The GCMS-TQ8040 is capable of accepting installation of two narrow-bore capillary columns into the MS simultaneously. This allows you...

Simplified GC-MS/MS method development Smart MRM makes method development quick and easy. Whether starting from scratch to optimize transitions and collision energies for new compounds, or starting from an MRM database of known target analytes to build a custom MRM method, Smart MRM takes the stress and difficulty out of method development. Pesticide Residue Analysis Metabolic Component Analysis Environmental Pollutant Analysis Forensic Toxicological Analysis

Smart Database Compounds and Optimized Transitions The Shimadzu “Smart Database” is a database of related compounds (e.g. pesticides, drugs, metabolites, etc.) with optimized transitions and collision energies, CAS registry numbers, and Retention Indices (RI) . The user can select from hundreds of pre-registered compounds in one of the “Smart Database” files, or add their own optimized transitions. The user selects the compounds to be analyzed, and Smart MRM builds the MRM or Scan/MRM acquisition method from the “Smart Database” with the push of a button. Smart MRM Automatic Method Creation...

Pesticide Quick-DB Pesticide Quick-DB is a software package that contains Scan/MRM and Scan/SIM acquisition methods and pre-stored calibration curves for more than 450 pesticides. The Pesticide Quick-DB uses isotopicaiiy labeled pesticide surrogates as internal standards for each compound class to enable rapid, semi- quantitative results. In addition, Scan/MRM simultaneously acquires qualitative mass spectra for confirmation. When used with the Twin Line MS System, detected compounds can also be confirmed on a second, dissimilar column without venting the MS. MRM Mass Chromatogram and Scan...

Metabolite Database Metabolic Component Analysis Biological samples such as blood serum contain large amounts of interfering co-extractants. Due to co-elution of components, some compounds cannot be reliably analyzed using single quadrupole GC-MS. MRM measurements eliminate the effect of interfering background matrices, and enable the targeted compounds to be accurately and reliably identified. Smart Metabolites Database registers MRM information of 475 metabolites mainly contained in biological samples such as blood, urine and cells. The database used in conjunction with the Shimadzu...

Smart Options Various System Configurations For GC-MS/MS analysis, different system configurations may be required depending on the application and sample-introduction needs. The GCMS-TQ8040 offers a wide variety of system configurations and sample-introduction devices to enable an expanded range of applications. Chemical Ionization and Negative Chemical Ionization In addition to commonly-used electron ionization (EI), both chemical ionization (CI) and negative chemical ionization (NCI) are available for the GCMS-TQ8040. The CI mode is a “soft ionization” technique, used to detect many...

HS-20 Headspace Sampler The GCMS-TQ8040 can also be used as a single quadrupole GC-MS. In combination with the HS-20 headspace sampler, it can analyze residual solvents in pharmaceuticals. If highly toxic impurities are discovered, even trace quantities can be quantified using MRM analysis. The HS-20 transfer line is built into the GC, so combination with a liquid sample injector using the AOC-20 as well as switchover operations are easy. AOC-6000 Multifunctional Autosampler ampler The AOC-6000 is compatible with three sample injection methods: liquid sample injection, headspace injection,...