High Recovery Vials Reduce Residual Product Waste by 99% A Cost-Effective Alternative for Pharmaceutical Product Packaging White Paper

For primary packaging, particularly of high-value products including biologics and some vaccines, a high recovery vial such as the NextGen™ V-Vial® provides long-term savings for pharmaceutical manufacturers. INTRODUCTION Pharmaceutical companies manufacturing billions of liquid doses each year risk significant product waste when using flat-bottom vials for end user packaging. According to the U.S. Pharmacopoeia (USP), "each container of an injection contains sufficient excess" of the labeled dose or size to allow withdrawal of the labeled quantity of drug.1 High Recovery Vials (HRVs) that feature...

STUDY RESULTS The residual volume measured in each flat-bottom vial averaged 116.9|ul_. For the E-Z Ex-Traction, average residual volume was recorded as 2.7p_, while for the NextGen V-Vial, residual volume was 1.1|u_, as shown in Table 1; n = 25 for all trials. The E-Z Ex-Traction and NextGen V-Vials both significantly decrease product waste. The E-Z Ex-Traction Vial offers a 97.7% decrease in wasted residual product, while the NextGen V-Vial offers a reduction of 99.1%. In addition, HRVs eliminate the possibility of end users "pooling" residual volumes from individual vials to create additional...

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