The API 5000™ LC/MS/MS System is one of the most complex bioanalytical samples. Designed to deliver the lowest limits of detection for the most demanding DMPK and ADME studies, the API 5000 System combines new QJet™ Ion Guide technology with the proven Turbo V™ Ion Source and a powerful new generation of Analyst® and MultiQuant™ Software. The result is a robust, versatile, high-throughput system with industry-defining quantitative performance,

small molecule analysis Ideal for small molecule analysis The API 5000™ LC/MS/MS System gives you exceptional accuracy and precision for quantitative analysis. It also offers linearity over a wide dynamic range and exceptional sensitivity for routine quantitation of low abundance compounds in complex matrices - with greater signal- to-noise than even the API 4000™ System. This chromatogram acquired at unit resolution of both Q1 and Q3 demonstrates outstanding S/N for 10 fg of buspirone injected on-column. The data are taken from one of the eight replicate injections of the lowest concentration...

Uncompromised performance Get expert results - even if you're not an expert Not only is the API 5000™ one of the most powerful triple quads available, it is also one of the easiest to use. From automated methods development to quick, simple routine maintenance, the API 5000 System makes it easy for you to get the answers you need, even if you are just getting into mass spectrometry. Unattended, high-throughput operation The API 5000 System is engineered for continuous duty operation in high-throughput regulated laboratories. With a full complement of advanced automation features, it fits seamlessly...

High throughput for the networked lab AB SCIEX combines one of the world's most sensitive mass spectrometers with the industry's leading software for robust, high performance quantitation. Analyst® Software delivers a new standard in compliance, throughput, and ease of use. The best quantitation tools for rapid results: reduce your integration, method development, and data review time Rapid acquisition method development: automate your compound optimization and tuning routines Intelligent integration: new parameter-free algorithms reduce time spent revising and reviewing results The most comprehensive...

Technology in a class by itself Innovative Turbo V™ Ion Source Efficiently ionizes compounds and virtually eliminates crosscontamination, even with large sample loads. Embedded ceramic heater technology and improved gas dynamics contribute to the system’s low detection limits and enable high-sensitivity quantitation over the wide range of flow rates used in pharmaceutical analyses. Quick-change ESI and APCI probes let you switch between ionization modes in seconds. Turbo V ™ Ion Source Curtain Plate Orice IQ1 Q1 Turbo V Source QJet™ Ion Guide Curtain Gas™ Interface Q0 High Pressure Cell ST ST2...

Proprietary Curtain Gas™ Interface Reduces the need for routine maintenance and ensures maximum uptime and productivity by protecting the interface region and quadrupole analyzer from contamination Revolutionary new QJet™ Ion Guide Replaces the skimmer in earlier triple quad designs, dramatically improving sensitivity. It captures more ions that enter the nstrument, efficiently separates them from neutrals, and focuses Curtain Gas™ Interface UNAC® Collision Cell IQ3 ST3 EXIT LENS DETECTOR

We invest in your success. As the world leader in mass spectrometry, AB SCIEX solutions are backed by the industry's most extensive service and support organization. With a network of service professionals, experienced compliance specialists, and over 1 50 PhD application scientists worldwide, we are dedicated to supporting your technical needs and helping you get the most out of your AB SCIEX service professionals are recognized as the most highly qualified in the industry. They are certified on our instrument platforms through a rigorous 4-step certification program, with re-certification occurring...