API 2000 ™ LC/MS/MS SYSTEM Triple quadrupole power and performance, at a single quadrupole price API 2000 ™ LC/MS/MS SYSTEM

Advanced MS/MS capabilities in a surprisingly sma The API 2000™ LC/MS/MS System from AB SCIEX brings the power and accuracy of tandem mass spectrometry to a wide range of applications. Designed for maximum reliability and ease of use in demanding high-throughput environments, this versatile, compact instrument offers tremendous LC/MS/MS capability in the space of a single quadrupole.

The technology of choice for a wide Triple quadrupole MS/MS is one of the most sensitive and specific approaches for small-molecule quantitation. The fragmentation capabilities of tandem mass spectrometry also provide critical information for structural elucidation of unknown compounds. Typical applications of the API 2000™ LC/MS/MS System • High-throughput pharmacokinetic screening • Metabolite identification • Impurity profiling Food & beverage • Analysis of veterinary drug and pesticide residues • Detection and quantification of disease agents and potential carcinogens Environmental analysis...

Technology that keeps your lab running at maximum productivity A selection of easily interchangeable ion sources and flexible, intuitive software make it easy to integrate the API 2000™ System into your applications and lab workflow. Convenient "plug-and-play" ion sources Rapid source change-over minimizes downtime and simplifies routine maintenance. All temperature, gas, and electrical connections are fully integrated into the source housing - no extra lines to attach and no lost time. Magnetic connections automatically detect hardware changes and adjust the software accordingly Robust ion sources...

3.0E+06 Area Response 2.0E+06 High sensitivity and reliability High-pressure collisional focusing in Q0 maximizes ion transfer from 1.0E+06 source to analyzer and ensures that even the most fragile compounds reach the analyzer intact. The system’s broad dynamic range minimizes the need for sample concentration or dilution. 0.0E+00 0 20 40 60 80 100 120 140 160 180 Injection Number Injection: 25 μL injections of terfenadine in Hank’s salt buffer solution HPLC: C8 HPLC (2.1 x 50 mm) with gradient elution of 500 μL/min mobile phase directly (no split) into TurboIonSpray® Source on the API 2000™...

LINAC® Collision Cell Optimized for high throughput The patented LINAC Collision Cell ensures exceptional sensitivity Automated methods development and data processing make the and performance in all modes of MS/MS operation – including API 2000™ System ideal for unattended, high-throughput, multiple reaction monitoring (MRM), neutral loss, and precursor ion quantitative analyses. scan modes. By allowing you to reduce MRM dwell times without compromising sensitivity, the LINAC Collision Cell significantly increases the number of compounds you can measure per analysis. Peak 1 420 400 380 360 340...

We invest in your success. As the world leader in mass spectrometry, AB SCIEX solutions are backed by the industry's most extensive service and support organization. With a network of service professionals, experienced compliance specialists, and over 1 50 PhD application scientists worldwide, we are dedicated to supporting your technical needs and helping you get the most out of your AB SCIEX service professionals are recognized as the most highly qualified in the industry. They are certified on our instrument platforms through a rigorous 4-step certification program, with re-certification occurring...