1. Catalogs
  2. SCIEX
  3. 4800 Plus MALDI TOF/TOF™ Analyzer

4800 Plus MALDI TOF/TOF™ Analyzer

4800 Plus MALDI TOF/TOF™ Analyzer

4800 Plus MALDI TOF/TOF™ Analyzer

Product catalog summary
Overview: The 4800 Plus MALDI TOF/TOF™ Analyzer is a powerful platform for quantitative proteomics, offering unparalleled depth of coverage and robust quantitation. It integrates advanced optics technology and innovative software to enhance performance and sensitivity.
Key Features:
  • System Design: Compact vertical design with OptiBeam™ on-axis laser irradiation for increased sensitivity.
  • Sample Handling: Utilizes single-use, industry-standard microtiter format Opti-TOF® sample plates for simplified operation and maximum throughput.
  • Software: ProteinPilot™ software with advanced Paragon™ and Pro Group™ algorithms for accurate protein identification and quantification.
  • Quantification: Supports 8-plex iTRAQ™ reagents for comparing and quantifying up to eight samples simultaneously.
Performance:
  • Sensitivity: Low attomole sensitivity in MS and MS/MS modes for confident peptide detection.
  • Mass Accuracy: Sub-15 ppm mass accuracy across the sample plate, with potential for 2.5 ppm using an internal standard.
  • Data Acquisition: Automated workflows with RDA™ features for efficient data collection and analysis.
Applications:
  • Biomarker Research: Precise quantification for protein biomarker discovery applications.
  • LC MALDI Analysis: Ideal for LC MALDI analysis with advanced peak-picking algorithms and Peak Explorer™ software.
Technological Advancements:
  • TOF/TOF™ Optics: Enhanced optics technology for improved performance and sensitivity.
  • QuanTIS™ Precursor Selector: High-resolution precursor ion selection without significant loss in sensitivity.
Conclusion: The 4800 Plus MALDI TOF/TOF™ Analyzer is an ideal system for accurate quantitative proteomics, offering unmatched sensitivity and advanced software tools for confident protein identification and quantitation.
See more

Catalog excerpts

4800 Plus MALDI TOF/TOF™ Analyzer-1

4800 Plus MALDI TOF/TOF > Analyzer >

 Open the catalog to page 1
4800 Plus MALDI TOF/TOF™ Analyzer-2

The 4800 Plus MALDI TOF/TOF > ٙ Analyzer takes TOF/TOF > optics technology to the next level of performance and sensitivity. The integrated system features a compact vertical design and novel OptiBeam > ٙ on-axis laser irradiation. >

 Open the catalog to page 2
4800 Plus MALDI TOF/TOF™ Analyzer-3

The Most Direct Path to the Answers The Ultimate LC MALDI Platform Smart, powerful workflows help you derive more useful information from every experiment.Օ Low attomole sensitivity in MS and MS/MS modes lets you confidently detect and identify peptides that other systems miss. Advanced, wizard-driven software allows easy setup of workflows and automatic tuning of the instrument to ensure maximum performance for every experimental run.Օ Compact, vertical design minimizes floor space requirements. The combination of unparalleled sensitivity and advanced, easy-to-use LC/MS software makes the 4800...

 Open the catalog to page 3
4800 Plus MALDI TOF/TOF™ Analyzer-4

Impressive MS and MS/MS Sensitivity Enhanced Precursor Ion Selection The 4800 Plus MALDI TOF/TOF Analyzer delivers unmatched sensitivity in both MS and MS/MS modes. This not only lets you see the ions of interest at a lower level than ever before; it means fewer laser shots are required to produce high quality spectra and faster analysis time. Higher sensitivity and fewer laser shots also conserve limited sample amounts in case further analysis is required. Advanced QuanTIS > precursor selector technology offers high resolution precursor ion selection with no significant loss in sensitivity....

 Open the catalog to page 4
4800 Plus MALDI TOF/TOF™ Analyzer-5

Mirror Region Source 2 Region Reflector Detector Source 1 Region Deceleration Stack Linear Detector Linear ion optics offer unparalleled high mass performance. Ion path in Reflector mode Laser path LaserCamera The deceleration stack optics prior to the collision cell enable the kinetic energy of the precursor ions entering the collision cell to be tuned for controlled fragmentation. This enables the user to obtain optimum fragmentation for a wide range of applications. QuanTIS PrecursorSelector Novel timed ion selector optics provide high resolution precursor ion selection without a significant...

 Open the catalog to page 5
4800 Plus MALDI TOF/TOF™ Analyzer-6

Search for Everything Isoform-Specific Quantitation With the Paragon > Algorithm over 100 post-translational modifications, up to 45 work-up modifications, and all amino acid substitutions (equivalent to 376) are searched ٓgiving a much higher percentage of correctly assigned spectra More than ever before there is emphasis on generating proteomics results that are quantitative. With well over 50 peer-reviewed publications that use iTRAQ > reagents for real research there has never been a better time to turn to a label-based quantitative approach. ProteinPilot > 1 ٔ and a higher sequence coverage....

 Open the catalog to page 6
4800 Plus MALDI TOF/TOF™ Analyzer-7

Ideal System for Accurate Quantitative Proteomics Optimized for LC MALDI The 4800 Plus MALDI TOF/TOF > Analyzer offers a new level of sensitivity for identifying and quantifying low abundance proteins in complex mixtures by harnessing the power of 8-plex iTRAQ The 4800 Plus system offers complete supportٗas well as fast, simple setup and configurationfor LC MALDI. By decoupling the mass spectral analysis from the chromatography separations, you can perform comprehensive MS and MS/MS analysis without the time constraints of LC.ו Peak Explorer > reagents. An expanded dynamic range enables robust...

 Open the catalog to page 7
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.