Valves for the Pharmaceutical and Fine Chemical Industries SchuF Broschüre Pharmaceutical Industries 09-11-2015 RZ.indd 1

Table of Contents Page Overview Disc Bottom Outlet Valves Stainless Steel, Hastelloy and other Alloys Glass/PTFE/PFA-lined Body Additional Sensor Options – Temperature Sensors, Lining Integrity Monitoring Ram Bottom Outlet Valves Stainless Steel, Hastelloy and other Alloys Bottom Outlet Valves with Integrated Sampling Systems Process Analytical Technology (PAT) in SchuF Valves Case Study: SchuF MultiProbe™ Valve- Bespoke PAT Case Study: Pharmaceutical Valve with PAT & Filtration Function Customer Enquiry Form Product Portfolio Overview SchuF is fully registered, accredited and certied worldwide...

Valves for the Pharmaceutical and Fine Chemical Industries Overview In recent years, the dual pressures of rationalisation and safety/environmental regulations have driven technical progress in the pharmaceutical and fine chemical industries, resulting in a number of significant developments. SchuF, which has partnered many of the world’s leading pharmaceutical companies in this field, have been at the forefront of these innovations for many years, and continue to investigate new possibilities while refining and improving existing products. The major concerns of manufacturers and processers working...

Disc Bottom Outlet Valves – St. St., Hastelloy and other Alloys Features SchuF flush-mounted bottom outlet valves see extensive service in the bulk pharmaceutical and fine chemical industries. They are often used in the production of core active-ingredient acids and vitamins. The Type 25 bottom-outlet Valve in Stainless Steel, Hastelloy (or other alloy) body and trim provides a solution where customers require a flush-mounted, custom-fit valve with high corrosion resistance and complete operational reliability in order to maximise their system’s high-level functionality. Bespoke design requirements...

Disc Bottom Outlet Valves – St. St., Hastelloy and other Alloys Standard Dimensions for common valve sizes Dimensions for other sizes available on request. Left: The valve seat is custom-fit to match the vessel bore dimensions. The external diameter of the seat (d1) is one millimetre less than the vessel bore. X The height of the seat (X) will also match the seat and allows for a gasket seal between the seat and the vessel. Cutaway View Left: Standard version Vessel Wall Above: GMP O-ring seal between seat-top and vessel wall Above: Low-profile version with side-mounted actuator Valve dimension...

Bottom Outlet Disc Valve – Glass / PTFE / PFA-lined Body Features SchuF flush-mounted bottom outlet valves see extensive service in the bulk pharmaceutical and fine chemical industries. They are often used in the production of core active-ingredient acids and vitamins. The Type 25 bottom-outlet valve with lining in glass, PTFE/PFA, tantalum, or other materials such as rubber, provides the ideal solution when customers require a flush-mounted, custom fitted valve with high corrosion resistance and complete operational reliability in order to maximise their system’s high-level functionality. Bespoke...

Bottom Outlet Disc Valve – Glass / PTFE / PFA-lined Body Features Additional options include temperature/PAT sensors, accessories such as positioners, limit switches or solenoid valves, actuator manual over-ride, leak detection and live-loaded packing. Flat seat with metal core, lined with PTFE/PFA Tall glass disc: Nozzle space filled without narrow dead-space Glass-lined spindleother linings available, such as tantalum Seat Options: Valve shown with tall disc (allowing easy cleaning) and flat seat Purge flangeClean-In-Place Seat Options: Valve shown mounted to a vessel with a pad flange, with...

Bottom Outlet Disc Valve – Glass / PTFE / PFA-lined Body Standard Dimensions for common valve sizes Standard seat and actuator Flat seat with standard actuator* Standard seat with side-mounted actuator Stroke Dimensions for other sizes available on request. *Note – Variables ‘X’ and ‘d1’ not applicable for flat-seat valves. Valve dimension table for lined Disc Bottom Outlet Valves, with standard Pneumatic Diaphragm Actuator 60° Size Imperial X Standard d1 Standard x min-max a b h1 H (PM) H (PS) Stroke Ø D2 All dimensions are in mm unless otherwise stated. Dimensions for other Bottom Outlet Valve...

Additional Sensor Options Temperature Sensor Functions SchuF Bottom Outlet Valves can be supplied with temperature measurement capability as a standard option. Retro-fit of existing valves is possible. 2xPT100 RTD, 4-wire, Class 1/3B sensors can be integrated into the disc and spindle to provide continuous real-time temperature measurement of the medium. The sensors are fitted at the medium’s lowest point. No additional vessel nozzles are required. In many cases the sensor can be removed for calibration without removing the valve from service. Glass Disc with integral Temperature Sensor Transmitters...

Ram Bottom Outlet Valve – St. St., Hastelloy and other Alloys Features SchuF ram valves have seen extensive service in the bulk pharmaceutical and fine chemical industries, handling both liquid and powder media. They are often used in the production of core active-ingredient acids and vitamins. The Type 28 Bottom outlet valve with Stainless Steel, Hastelloy (or other alloy) body and trim (PFA lining is also possible) provides a solution where customers require a flush-mounted, custom-fit valve with high corrosion resistance and complete operational reliability in order to maximise their system’s...

Bottom Outlet Valves – Draining and Sampling Systems Multiple Benefits SchuF offers a number of draining and sampling systems which operate through a single valve connection point. For example, Schuf supplies a combination of a ram-type drain valve with an integrated laterally mounted wafer-type sampling valve, Type 28PF. Advantages of this system include: o need for an extra, dedicated vessel port N for sampling nused sample is simply returned into the U vessel – no waste Above: The type 28PF sampling system allows a variety of operational steps to be carried out in any sequence, with repetitions...