Solutions for Drying, Granulating and Coating Small Particles
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beyond technology ^ Herbert Huttlin Solutions for Drying, Granulating and Coating Small Particles

Beyond Technology The new business model from Romaco sets valuable incentives for meeting customer requirements. For the design of innovative solutions, Romaco relies on its unique knowledge portfolio. With its diverse brands, Romaco focuses on important technological fields of competence. The single product lines offer the optimum prerequisite for the development of comprehensive solutions. Romaco promises its customers professional project handling, fast delivery times and a reliable service. Through this, Romaco provides its customers with a considerable boost to their earning and...

» As an innovation leader for drying, granulation and coating, Romaco Innojet offers a range of high-efficiency processing solutions for the pharmaceutical, food and chemical industries« Zeljko Pockaj, Managing Director Romaco Innojet Delivering Solutions We Improve your Return on Investment The VENTILUS® technology was developed by Romaco Innojet for a broad array of applications involving small particles - from classic drying processes in combination with a high-shear mixer to innovative pellet or hot melt coating. Within these applications our customers acquire a standardised...

Powders, crystals Small pellets Large pellets Small tablets Gelatine capsules Special shapes Drying, Granulation & Coating Particle size Laboratory scale (1.5 – 5 I batches) ® Pilot scale (10 – 50 I batches) Production scale (40 – 1,600 I batches) Granulation of Powdery Substances VENTILUS®-Compatible Starter Materials • Improved flowability and dosing properties • Preparation for tableting • Dust binding • Different raw materials combined without segregation • Optimised release kinematics • Powders, crystals, granulate, pellets or micro-tablets • All free-flowing bulk materials from 10 µm...

Delivering Solutions Air Flow Bed Technology All Romaco Innojet solutions for drying, granulation and coating small particles are based on the air flow bed technology originally developed and internationally patented by Dr. h.c. Herbert Huttlin. This method optimises the fluidisation of solid particles and creates flow conditions that enable extremely gentle intermixing of the product. The air flow bed technology provides significant benefits for our customers compared to granulation and coating systems based on a conventional fluidised bed. Characteristics of the Air Flow Bed Technology •...

Granulation and hot melt coating in the VENTILUS® V 400 Granulate with hot melt coating Shorter Batch Times Optimised Process Control • Drying, granulation and coating combined in a single batch process (3-in-1) • Multilayer coating: seamless sequence of individual spraying steps • Drying times up to 25% shorter • Higher productivity compared to conven­ tional, conical product containers owing to the cylindrical container geometry • Efficient intermixing of the product with the innovative spraying system • Large product surface facilitates the application of liquid coating or adhesive...

Coated pellets Coated micro-tablets Hot melt coated granulate Coated apple pieces Coated seeds Coated seeds Coated fertiliser pellets

Laboratory Scale Pilot Scale Product Trials Worldwide Exploiting Technologies VENTILUS® V 5 laboratory scale systems are specially designed for manufacturing small batches from 1,500 ml to 5,000 ml. They are excellent process development solutions for our customers in the pharmaceutical, food and chemical industries. The pilot scale systems in the Romaco Innojet VENTILUS® series are intended for batch sizes from 10 to 50 litres. They are ideal for clinical samples as well as for analysing and validating process parameters. VENTILUS® laboratory equipment is in­ stalled at all our Sales and...

+ Increased inlet air capacity + Central air supply + Slide-out nozzle support allows in-process nozzle changes + Increased inlet air capacity + Central air supply Long batch times Pellets, API coatings, catalysts, micro-tablets + Combination with high-shear mixer + Spraying system + Hot melt spraying (optional) + Spray air heater (optional) + Central air supply heater (optional) + Hot melt coating (optional) + Spray air heater (optional) + Central air supply heater (optional) + Hot melt coating (optional) + Spray air heater (optional) Granules, powders Application flexibility Process...

Production Scale GMP Granulation Line Concept Optimised Cleaning Exploiting Technologies • Batch sizes from 40 to 1,600 litres • Larger batch volumes or modifications on request • Suitable for use in the pharmaceutical, food and chemical industries VENTILUS® systems can also be used as part of a multi-purpose wet granulation line in combination with a high-shear mixer. Owing to their application flexibility, they are ideal for contract manufacturing. The closed material transfer system has a built-in conical mill for wet and dry milling. • WIP – washing in place: product-con­ tacted parts...

beyond technology ^ Herbert Huttlin

ORBITER ORBITER is the name given to the container bottom or booster through which process air is introduced. Its special design supports the formation of the orbital air flow bed. It consists of overlapping circular plates. • Process air introduced between the circular plates • Formation of the air flow bed by means of controlled air distribution with a precisely defined flow velocity • Spiral, orbital movement guarantees gentle, uniform intermixing of the product • Horizontal arrangement of the ORBITER's circular plates prevents the product from dropping through, even if the process...

Case study: Taste masking of granules 85% shorter processing time with hot melt coating compared to coating with a polymer solution Hot melt coating Wachs 500g 42 min Granulate with coating 1500g Wachs Application: 50% 42 500g 278 min H 2O Spray rate: 12g / min min Coating with polymer solution Granulate 1000g Exploiting Technologies 278 min Granulate with coating 1500g Technology Leader in the Hot Melt Sector Romaco Innojet Hot Melt Device IHD 5 VENTILUS® systems are ideal for hot melt applications, in other words for granulation and coating with organic wax and hard fats. The Romaco...