Innovative Mixing Solutions the way you think about ff formulating pharmaceuticals PharmaRAM” II PharmaRAM™ II Key New Features: • 2.2 lbs. (1 kg) capacity. • Computerized, touch-screen user interface • Program and store recipes and operational data • Specifically designed for pharmaceutical processing • Jacketed vessel for heated or cooled mixing • Up to three temperature sensors • Bar-code reader input capable • Built-in strobe light Innovative Second Generation Technology Topicals Designed for improved mixing that is faster, cleaner, and safer, the PharmaRAM™ II introduces significant benefits of ResonantAcoustic® Mixing (RAM) technology at a 2.2 lbs. (1 kg) scale. Pharmaceutical formulations and compounded medicines processing can achieve higher quality and lower cost. The PharmaRAM™ II is well suited for mixing of liquids and powders, as well as pastes, creams, and ointments. Since being introduced in 2007, RAM mixers have become the processing technology of choice at many developmental, formulating, and production facilities. A primary reason is RAM’s ability to consistently achieve less than 4%, even less than 2%, relative standard deviation (RSD) across a wide range of excipients and API combinations. (Please see the RSD Mix Test Results chart on reverse side.) The advanced design features incorporated into the PharmaRAM™ II reflect design and operational considerations from many ResonantAcoustic® Mixing users in compounding and pharmaceutical communities. PharmaRAM™ II utilizes low-frequency, high-intensity acoustic energy to rapidly fluidize and disperse material. PharmaRAM™ II is a non-contact mixing technology; completely and uniformly mixing without the use of impellers, blades,

Innovative Mixing Solutions the way you think about formulating pharmaceuticals PharmaRAM ™ II ResonantAcoustic® Mixing delivers exceptional, highly repeatable RSD results 30 common API/excipient mixes tested achieved <4% RSD requirement in under 2 minutes of mixing time dfc- RAM Mix Test Results 4% “Readily |-| Pass” RSD level FDA Guidelines U Eliminate manual mixing variability Programmed operation for repeatable results Superior potency through content uniformity Rapid mixing reduces processing time Sealed mixing vessel enhances safety Automatic operation reduces repetitive motion No cross...