Innovative Mixing Solutions Resonant Acoustic® Mixing Hydrating Hydrocolloids Resodyn Acoustic Mixers has developed a novel mixer product line that uses low-frequency, highintensity sound energy for mixing. The mixer technology, trademarked as ResonantAcoustic® Mixing, is applicable for a broad range of mixing regimes that include liquid-gas, liquid-liquid, liquid-solid and powder-powder systems. Highlighted in this bulletin is: Hydrating Sodium Carboxymethyl Cellulose. This bulletin demonstrates the use of Resonant Acoustics® for hydration. Hydrating Hydrocolloids A formulation of Sodium Carboxymethyl Cellulose (NaCMC) and water was mixed. Current methods employ stir bars that may take many hours to fully hydrate the NaCMC. The image on the left depicts the starting materials, while the image on the right shows the hydrated NaCMC in the mixing container after mixing using Resonant Acoustics® . The starting materials were 200 grams of water and 2 grams of NaCMC. The materials were mixed for 10 minutes. At the end of the mixing, the NaCMC was fully hydrated. There were no clumps of NaCMC remaining. Final viscosity matched requirement of 1000 -3000cps. The use of RAM® technology is well suited for hydrating materials. This may be applied to pharmaceutical and chemistry formulations. Starting Materials RAM5 Mixer for production and process development. Resonant Acoustic® mixing also alleviates contamination or clean up concerns as the mixing is performed in a sealed container with no mixing blades in the mix container. ResonantAcoustic® Mixer Benefits • • • • Remote operation Blends dissimilar powders Fast mixing times Can mix in the shipping container Solids, liquids, & gels Can mix hazardous materials Hydrations Viscous and Aqueous solutions Resodyn Acoustic Mixers, Inc. 130 North Main Street, Suite 630 Butte MT 59701 406-497-5333 [email protected] www.ResodynMixers.com LabRAM Mixer for lab use and small volume production ba