UNISTAT® Bilirubinometer Brochure
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UNISTAT® Bilirubinometer Brochure - 1

Reichert UNISTAT® Bilirubinometer Chemistry-free, no dilution solution for point-of-care Total Serum Bilirubin measurement • imple to operate. Requires no complicated chemistry or waiting time. S • NISTAT®’s photometric analyzer measures Total Serum Bilirubin (TSB) U concentration easily and accurately within 5 seconds. • NISTAT® provides 99% correlation to widely recognized method U (diazo Jendrassik-Grof ) for accurate TSB measurement.1 • Low operating cost with no expensive slides, carousels, or reagents. UNISTAT® uses an inexpensive disposable specimen cuvette and re-usable glass calibration cuvette. Clinical Implications: Bilirubin is a byproduct of the breakdown of hemoglobin by the liver. Newborns may have difficulty with filtering blood and excreting this excess bilirubin. Because of this risk of bilirubin toxicity, newborns must be monitored to identify those who might develop hyperbilirubinemia and kernicterus. The Total Serum Bilirubin test measures the concentration of bilirubin in the newborn. This detection is needed before a diagnosis and treatment program can be initiated. • study published in the Journal of Perinatology showed that UNISTAT® meets the A 2004 AAP guidelines “Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation” for physicians taking TSB measurements as a point-of-care test (J Perinatol. 2006; 26:100-105). 2* Point-of-care testing for all skin types and ethnicities. Reichert’s UNISTAT® Bilirubinometer uses a proven photometric analyzer to provide accurate and rapid measurements of total serum bilirubin (TSB) concentration in undiluted serum. The photometric analyzer is the ideal STAT-level analyzer for determining TSB in newborn infants. Other methods use visual detection of skin color. This has proven to be unreliable where skin color pigments can mask the jaundice symptom. continued Contact Charlie Smith: 716-319-4777 Charlie.Smith@Ametek.com Reichertai.com H A Barko, G L Jackson, W D Engle; Evaluation of a point-of-care direct spectrophotometric method for measurement of total serum bilirubin in term and near-term neonates; Journal of Perinatology; 01 Feb 2006; 26, 100 - 105 1, 2 *Mention of the AAP guidelines does not imply endorsement of an

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UNISTAT® Bilirubinometer Brochure - 2

Reichert UNISTAT® Bilirubinometer Principles of Operation: The Reichert UNISTAT® is a direct spectrophotometer that measures total bilirubin in neonatal serum samples. Dilution is not necessary. A beam of light is passed through the sample cuvette. The beam is split by a dichroic mirror and directed toward the 460nm and 550nm filters. The transmittance of the light exiting the filters is measured by photodetectors. The control electronics calculate total bilirubin based on output from the photodetectors. Since peak absorbance is shared by bilirubin and oxyhemoglobin at 460nm, it is...

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