GloMax Discover and Explorer
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GloMax® Discover State-of-the-art multimode readers absorbance detection.

Integrated Assays The intuitive touchscreen display, preloaded protocols and automatic instrument gain adjustments make it simple to produce your data and analyze results. Optimized, preloaded Promega protocols are part of the GloMax® Systems Software, minimizing time spent optimizing instrument settings. Select the detection modules you need. Place on a bench top or integrate into a larger automated platform for higher throughput. OVERVIEW VIDEO Superior Performance World-Class Service A broader dynamic range measures high and low samples within the same experiment, resulting in better...

The Right Instrument for Your Needs GloMax® Discover and Explorer offer a range of detection options. Purchase the instrument and modules you need now. Upgrade your system later as your laboratory needs change. KH j , , „ Visible UV-Visible BRET and Model Luminescence Fluorescence _. , _. , ™„ Absorbance Absorbance FRET B(aloMax® Explorer Upgrade Upgrade Upgrade ^'°JIV!^Xl!^IOrer %/%/%/ Upgrade Upgrade

Unpack, Plug In and Start Generating Data Automatic Instrument Adjustments No manual gain adjustment for luminescence reads. Optimized settings are set automatically. Reporting Preloaded software provides many of the required technical elements of a part 11 compliant system when used with the appropriate laboratory workflow. Minimal Manual Intervention Easily multiplex assays with automated filter switching, gaining more data from a single well. Measure cell viability and gene reporter activity with the touch of a button. Data Analysis Easily measure and analyze your results using the...

Automatic Filter Slides • Multiple reads without user intervention • Easily perform BRET and FRET studies • Customize filters for your needs Flexible Interface • Select a preloaded protocol or customize your own • View data in a heat map display • Easily export your results to a variety of locations ceo:*, OJOOHJ CUOOMJ iuoftrta owira oanai <M»IS OODIEJ ■ WQ _J/\\ eoojo7 aoo::5 ow:n OOOJOT O.OOJ O.DOI« DOO? 0.0019 040296 0.00291 OutBiift oj»iii JWJO; ft Drag and Drop Protoc

Integrated with Promega Assays Superior performance for a wide array of assays for your research. The sensitivity, broad dynamic range and low well-to-well cross talk provide you with more usable and relevant data. Developed and Optimized at Promega • 50 preloaded protocols • Optimized settings produce data more quickly • Protocols available for: • Nucleic acid quantitation for next-generation sequencing • BRET and FRET for protein interaction analysis • Kinase and cell signaling assays • Reporter gene assays • Multiplexing assays • Cell-based assays • Bioassays • ELISAs Select your...

Versatility and Performance Easily read multiplexed cell viability, apoptosis and cytotoxicity assays. Efficiently read the output of kinase inhibitor screening and automatically analyze results. [digitonin], µg/ml Multiplexed cytotoxicity and viability assays performed on digitonintreated K562 cells. Percent Activity Cytotoxicity (CellTox™ Green) Percent Vehicle Control (Viability) Screen Kinase Inhibitors Percent Vehicle Control (Cytotoxicity) Multiplex Assays Receptor tyrosine kinase inhibition was assessed following incubation with gefitinib, a selective inhibitor of EGFR, using the...

State-of-the-Art Sensitivity Assess Reporter Bioassays Detect luminescence from Promega bioassays and evaluate mAb activity. Study Protein:Protein Interactions Analyze the interaction of proteins using BRET. 14 12 mBRET Ratio ADCC Bioassay Target cells were incubated with a series of concentrations of Control Ab, Anti-CD20, followed by addition of ADCC Bioassay Effector Cells. A dose-response curve showing the disruption of the p53 and MDM2 interaction using the inhibitor Nutlin-3 in a Nan

Flexible Workflow Use on a bench top or integrate into your automated workflow for higher throughput and walk-away operation. Automation Ready Controlable by third-party scheduling software with liquid handling and plate stackers. The software is SiLA compatible, making integration device control simple as standards evolve. Third Party Integration Can be integrated with: • Tecan Freedom EVO® • Hudson Robotics Solo™ • PlateCraneEX™ • Hamilton Microlab® STAR series • many other har

Single-Source Service and Support Backed by a comprehensive one-year standard warranty, and our expert technical and service support teams. One Call Supports It All We supply the reagents and the instrument, so our expert technical support can answer all your questions. Additional support ensures minimal downtime when service is needed: • Instrument loan program • Service packages • Extended warranty Learn more about our extensive service products at: www.promega.com/GloMaxServ

GloMax Systems Specifications ® Luminescence • ow-noise PMT ensures collected light is not compromised L • 0 to 1,000 times more sensitive than competitor instruments 1 • o need to dilute samples or manage gain settings N • to 3 logs more usable data than competing instruments 2 • Filtered luminescence readout for BRET or multi-wavelength distinction (for GloMax® Discover only) or total luminescence • Lower cross talk for more usable data • ive filters included for BRET and filtered luminescence assays such as NanoBRET™, Renilla/YFP BRET F and Chroma-Glo™ (for GloMax® Discover only) • Or,...

GloMax® Systems Specifications • Uses powerful wavelength-matched, light-emitting diodes (LED) as excitation sources • LEDs closely match excitation profiles of commonly used fluorescent molecules to ensure high sensitivity • Reduces nonspecific light leakage, a common problem when using broad-spectrum light sources • Five excitation and emission filters included for common fluorescence assays; plus 1 customizable excitation and emission position • Or, customize two fluorescence excitation positions or all 6 emission positions to your needs Fluorescence Module Specifications Detector...