1. Catalogs
  2. Physik Instrumente
  3. Precision Drives for Electron Microscopy
video corpo

Precision Drives for Electron Microscopy

Precision Drives for Electron Microscopy

Precision Drives for Electron Microscopy

Product catalog summary
Overview: The document discusses precision drives used in electron microscopy, specifically for positioning and moving specimens in various types of electron microscopes such as TEM, Scanning TEM, Cryo-TEM, and SEM. It highlights the importance of precise nanopositioning and scanning for image reconstruction, especially in Cryo-TEM, which requires thousands of images from different angles due to low contrast in samples.
Applications: Electron microscopy is used in semiconductor inspection, materials research, and molecular biology. Cryo-TEM has been pivotal in COVID-19 research, helping to identify the protein structure of the SARS-CoV-2 virus.
Drive Requirements: Precision drives are needed for multiple dimensions of freedom, typically between three and six, including XYZ, rotations, and tilt movements. Drives must operate within vacuum chambers with pressure requirements between 10-4 mbar to 10-6 mbar, use non-magnetic materials, and withstand cryogenic temperatures.
Motion Solutions from PI: PI offers various drive solutions, including stacked drives and miniature hexapods. Examples include:
  • P-752 High-Precision Nano-positioning Stage: Offers repeatability of ±1nm and a travel range up to 35 μm, UHV compatible, non-magnetic.
  • N-310 NEXACT Miniature Linear Motor: Travel range of 10 to 125 mm, resolution of 0.03 nm (open loop) and 5 nm (closed loop), UHV compatible, non-magnetic.
  • P-911 UHV-Compatible Miniature Piezo Hexapod: Position resolution down to 0.1 μm, UHV-compatible to 10–9 hPa, non-magnetic.
Cryo-TEM Sample Vitrification: Involves placing a nanoliter droplet of liquid specimen onto a metal grid, which is then vitrified at about -160°C using ethane jets.
Vibration Damping: Electron microscopes require precise vibration isolation. Active vibration cancellation stages can be designed using PICA Stack Actuators or PICMA® Piezo Linear Actuators, which compensate for ambient vibrations.
See more

Catalog excerpts

Precision Drives for Electron Microscopy-1

Precision Drives for Electron Microscopy Precision Drives for Positioning and Moving of Specimen in TEM, Scanning TEM, Cryo-TEM, SEM and for the Vitrification of Samples for Cryo-TEM Onto Metal Grids Physik Instrumente (PI) GmbH & Co. KG, Auf der Roemerstrasse 1, 76228 Karlsruhe, Germany Phone +49 721 4846-0, Fax +49 721 4846-1019, Email [email protected], www.pi.ws

 Open the catalog to page 1
Precision Drives for Electron Microscopy-2

Precision Drives for Electron Microscopy Electron Microscopy Applications for electron microscopy cover a broad spectrum from semiconductor inspection, through materials research to molecular biology research. In conventional TEM as well as in the newer Cryo-TEM, which was awarded the Nobel Prize in 2017, the samples have to be precisely nanopositioned with precision in an XYZ coordinate and then tilted around one axes to produce a certain number of transmission images for image reconstruction. Especially in the Cryo-TEM, which uses very thin, vitrified slices of samples of typically 50nm thickness,...

 Open the catalog to page 2
Precision Drives for Electron Microscopy-3

Precision Drives for Electron Microscopy Motion Solutions from PI Typically the drive requirements for 3, 4, 5 or 6 - dimensions of freedom are solved by stacked drives. But also a fully parallel kinematic drive in form of a miniature hexapod is available. Some examples for potentially suitable drives, below. Cryo-versions only on specific request:  P-752 High-Precision Nano-positioning Stage Piezo-flexure stage, capacitive sensors, repeatability: ±1nm, travel range to 35 μm, UHV compatible, nonmagnetic Solutions for Cryo-TEM Sample Vitrification With the Cryo-TEM sample vitrification, first...

 Open the catalog to page 3
Precision Drives for Electron Microscopy-4

Precision Drives for Electron Microscopy © Ebystk temente.(PI) GmbH & Co. KG All contents, including texts, graphics, data etc., as well as their layout are subject to copyright and olher protective law's. Any copying, modi- hcation cr redistribution in whole or in parts is subject to a written permission of PI. Although the information in this document has been compiled with the greatest care, errors cannot be ruled out completely. Therefore, wre cannot guarantee for the information being complete, correct and up to date. Illustrations may differ from the original and are not binding. PI reserves...

 Open the catalog to page 4

All Physik Instrumente catalogs and technical brochures

  1. A-143

    5  Pages

  2. A-811.CE

    3  Pages

  3. G-902.RxI

    5  Pages

  4. P-405

    4  Pages

  5. PRYY

    7  Pages

  6. A-523

    5  Pages

  7. L-812

    18  Pages

  8. RS-40 V7

    4  Pages

  9. A-68x

    4  Pages

  10. G-901

    9  Pages

  11. G-910.RC02

    6  Pages

  12. F-712.IRP

    6  Pages

  13. C-663.12

    3  Pages

  14. C-887.53x

    5  Pages

  15. L-402

    5  Pages

  16. P-840

    4  Pages

  17. M-238

    5  Pages

  18. L-220

    5  Pages

  19. P-725

    9  Pages

  20. C-413

    3  Pages

  21. U-628

    3  Pages

  22. P-545.3D8S

    5  Pages

  23. A-131

    5  Pages

  24. d-891

    1  Page

  25. A-65x

    4  Pages

  26. A-60x.MTT

    1  Page

  27. A-80x

    3  Pages

  28. A-322

    3  Pages

  29. A-110

    3  Pages

  30. A-141

    3  Pages

  31. A-121

    5  Pages

  32. A-123

    5  Pages

  33. DT-34

    4  Pages

  34. A-10x

    3  Pages

Archived catalogs

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.