PROPER VACCINE STORAGE AND HANDLING PRACTICES Failing to keep the cold chain at the required temperature costs lives.

Vaccine Storage and Handling: Current Considerations and Trends Failing to keep the cold chain at the required temperature costs lives. Covering the Temperature Range for COVID-19 Vaccines Varying vaccine storage requirements demand precise positioning of equipment around the world. Maintaining Cold Chain Integrity (Infographic) As COVID-19 vaccine distribution ramps up, cold chain matters now more than ever. Excellence in Cold Chain Storage The quality of the cold determines the efficacy of internal storage conditions.

Evolving quality and design standards to meet demands of new research HC refrigerants and inverter technology work together to reduce energy consumption by 64% compared to conventional models. Sliding Door Pharmaceutical Refrigerators

Vaccine Storage and Handling: Current Considerations and Trends Failing to keep the cold chain at the required temperature costs lives. Making an effective vaccine faces significant obstacles, but it can’t protect people without proper storage and handling, which depend on a complete line of pharmaceutical-grade refrigerators and freezers that maintain the necessary conditions to keep vaccines safe and effective. According to the U.S. Centers for Disease Control and Prevention’s Vaccine Storage and Handling Toolkit: “Proper vaccine storage and handling are important factors in preventing and...

development pose novel challenges. For example, RNA contains a hydroxyl group that can be disrupted by hydrolysis, and that makes RNA less stable than DNA. Consequently, the vaccines in development for COVID-19 require special cold storage equipment, such as ultralow freezers. Even before working on these vaccines for COVID-19, scientists saw the great potential in building vaccines from mRNA, but researchers also knew that most mRNA vaccines needed to be stored at –70° C, which put a premium on developing formulations that could be stored at higher temperatures. So far, all mRNA vaccines require...

Covering the Temperature Range for COVID-19 Vaccines Varying vaccine storage requirements demand precise positioning of equipment around the world. Cold chain challenges loom ahead for a safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. On September 4, 2020, The Wall Street Journal reported: “The race to distribute Covid-19 vaccines to hundreds of millions of Americans could come down to one question: Do we have enough freezers?” With some of the vaccines in development requiring some storage steps at –80° C, the Journal adds:...

via a lipid nanoparticle, which protects the mRNA from nuclease degradation. Upon delivery to a clinical site, the vaccines will be thawed, but then a vaccine will only be good for a short period of time. The mRNA-based COVID-19 vaccine being developed by BioNTech/Pfizer can be kept at 2–8° C for as many as five days where it will be administered. Conversely, a DNA-based vaccine in development for COVID-19 could be effective for a year at 2–8° C. The specific conditions will evolve as vaccines move through development and approval. Plus, different conditions will be required from procuring raw...

Maintaining Cold-Chain Integrity The cold chain matters more than ever in the battle against COVID-19 because some of the vaccines in development require very low temperatures from production through patient inoculation. From vaccine manufacturing to distribution and administration, actions taken throughout the process determine the efficacy and safety of a vaccine for patients. In each step, the required cold storage must meet several key criteria: accuracy, uniformity, recovery after opening, and ambient tolerance. Vaccine Manufacturer Vaccine Vaccine Distribution Manufacturer Vaccine Arrival...

A healthy head start Supplying the chain A complete line of cold-storage devices—such as PHCbi’s refrigerators through ultra-low freezers—will be required for protection in every step. All aspects of a specific vaccine and its components and processing will determine the temperature needed along the way. To ensure safety and efficacy, there will be precise temperature specifications for raw materials, R&D, manufacturing, distribution, storage, and handling. With various vaccines in development, it’s difficult to determine the range of cold-storage platforms that will be needed. As a result, the...

Excellence in Cold Chain Storage The quality of the cold determines the efficacy of internal storage conditions. IT’S THE QUALITY OF COLD THAT DETERMINES THE EFFICACY OF INTERNAL STORAGE CONDITIONS. processes delivers a quality of cold that characterizes PHC Corporation’s commitment to engineering, storage safety and reliability. PHCbi pharmaceutical refrigerators, Biomedical freezers and pharmaceutical refrigerator with freezers combo refrigerators/freezers represent more than fifty years of engineering excellence in cold chain storage and temperature controlled products. From the refrigeration...

PHCbi MPR Series Pharmaceutical Refrigerators and Freezers vs Domestic/Household Products PERFORMANCE Precise Temperature Setting, Digital Display Microprocessor Control, ±2.0°C Accuracy Uniform Top-to-Bottom Temperature Fast Temperature Recovery Reserve Cooling Power Ambient Temperature Protection High Performance Insulation Protection from Vaccine Freezing Tight Temperature Uniformity To Protect Stored Product From Freezing Design Attributes Dual Panel Glass Door Integrated Systems Supervision Microprocessor Monitoring Deviation Alarms Temperature, Door Ajar Remote Alarm Terminal Standard NO/NC/C...

COVID-19 Vaccine Development is Evolving PHCbi HAS THE COLD CHAIN STORAGE YOU NEED New vaccines are emerging in response to the COVID-19 pandemic. Early evidence suggests novel vaccine storage temperatures may require a wider range of the cold chain spectrum. Some vaccines may require multiple temperature storage points prior to administration. Are you prepared for emerging COVID-19 vaccine storage? PHCbi brand products can help1. PHCbi brand pharmaceutical refrigerators and biomedical freezers offer a comprehensive selection of storage solutions for high-value vaccines and other biologics. These...