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MCO19-AIC/M Incubators

MCO19-AIC/M Incubators
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MCO19-AIC/M Incubators

Product catalog summary
Overview
The document details Panasonic's MCO-19AIC and MCO-19M CO2 and Multigas Cell Culture Incubators, designed for research, clinical, and regulated applications. These incubators provide advanced contamination control and a rapid decontamination process, making them suitable for high-value cell protocols.

Decontamination Features
The incubators offer a unique H2O2 decontamination option that minimizes downtime to under three hours. This process decontaminates all interior components and gas sampling loops in situ. The SafeCell UV system treats interior airflow to eliminate contaminants, while InCu saFe® copper-enriched stainless steel surfaces offer constant germicidal protection.

Control and Monitoring
Equipped with a multi-function LCD, the incubators allow easy programming of set-points, alarms, and controller functions. Precise PID control logic ensures stable CO2, O2, temperature, and humidity conditions. Multi-point data logging and an optional PC interface support remote transmission for GMP/GLP protocols.

Applications
The MCO-19AIC and MCO-19M are ideal for stem cell research, tissue regeneration, in vitro fertilization, genomic and proteomic expression, and hypersensitive cell culture.

CO2 and O2 Control
The incubators use a proprietary single-beam, dual detector infrared CO2 sensor for precise control and quick recovery after door openings. The MCO-19M model includes a zirconia O2 sensor for fast O2 level control.

Temperature and Humidity Control
The Direct Heat and Air Jacket conditioning system regulates temperature through multiple heating zones. The humidity pan is easy to fill and clean, with an automatic optical sensor indicating low water levels.

Cabinet Design
The incubators have a 170-liter capacity, are stackable, and feature field-reversible doors. Interior components and adjustable shelves are designed for easy access.

H2O2 Decontamination Process
The H2O2 decontamination process includes a seven-minute vaporization cycle followed by a 90-minute UV resolution phase, ensuring complete decontamination of the incubator's interior surfaces and components.

Comparison with High Heat Models
The H2O2 system offers advantages over high heat sterilization, including reduced downtime and no need for component removal, allowing frequent decontamination with validation for high-value GMP protocols.

SafeCell UV System
The SafeCell UV system includes a programmable UV lamp that decontaminates conditioned air and humidity reservoir water, preventing contamination without affecting cell cultures.

Conclusion
The Panasonic MCO-19AIC and MCO-19M incubators provide a secure environment for delicate cells, offering advanced contamination control and rapid decontamination, making them ideal for critical applications in biomedical and pharmaceutical research.

InCu saFe® Construction
The incubators feature InCu saFe® copper-enriched stainless steel alloy interiors, providing passive germicidal protection without rust or corrosion. This material inhibits the growth of molds, fungi, mycoplasma, and bacteria.

Intelligent Control Interface
The incubators are managed by a microprocessor controller with a graphical LCD, offering features like set-point programming, alarms, and data logging.

Specifications
The incubators are certified as Class IIa Medical Devices and comply with ISO standards. They offer features like stackable design, reversible doors, and adjustable shelves.

Options
Available options include H2O2 decontamination kits, SafeCell UV systems, and automatic CO2 cylinder changeover systems.

Product Specifications and Components
Includes roller base, InCu saFe® shelf and brackets, and half tray system. Communication interfaces include RS-232C/RS485, LAN, and Analog 4-20 mA.

Certifications
The Panasonic Healthcare Co., Ltd., Gunma factory is certified for ISO9001, ISO13458, and ISO14001.

Contact Information
Contact details for UK, Head, and France offices are provided for further inquiries.
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Catalog excerpts

MCO19-AIC/M Incubators-1

CO2 / Multigas Cell Culture Incubators MCO-19AIC / MCO-19M A secure environment for delicate cells The industry’s most complete cell culture solution for research, clinical and regulated applications. Securing samples, changing lives Now with safe, effective and documented three-hour in situ H2O2 decontamination option for fastest turn- around and maximum availability.

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MCO19-AIC/M Incubators-2

Ideal for Regulated or Sensitive Applications Advanced performance and design allows the MCO-19AIC and MCO-19M to be used with These include: confidence in high-value cell protocols among Genomic and proteomic expression Esoteric plant and amphibian cell culture Hypersensitive and transgenic cell culture decontamination between processes. or protocols that require a strict isolation and contamination, ultra-sensitive media and reagents, Autologous tissue regeneration & regenerative medicine hard-to-grow cell lines, cells highly sensitive to Stem cell research Low media volume microplate work...

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MCO19-AIC/M Incubators-3

The Panasonic MCO-19AIC CO2 Incubator and MCO-19M Multigas incubator are designed for demanding and regulated applications in the biomedical, pharmaceutical, medical research and clinical laboratory. Representing years of research, development and component testing, the MCO-19AIC and MCO-19M offer outstanding performance and advanced, multi-level contamination control to provide the ideal solution for cell culture protocols. (also requires SafeCell UV) (also requires SafeCell UV) InCu saFe® Copper Enriched Stainless Steel Interior Standard Single Beam, Dual Detector IR CO2 Sensor Direct Heat...

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MCO19-AIC/M Incubators-4

Continuous Active Background Contamination Control fights contamination while cell culture protocols are in process without downtime or compromise to the incubator’s performance. The patented SafeCell UV treats interior airflow to destroy airborne and humidity pan contaminants and InCu saFe® copper-enriched stainless steel interior surfaces assure constant germicidal protection. When total chamber decontamination with verification is required, the unique H2O2 decontamination option limits downtime to less than three hours. Hydrogen Peroxide Vapour Decontamination The use of low temperature H2O2...

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MCO19-AIC/M Incubators-5

Incubator configured for decontamination sequence. Interior components are reoriented for in situ decontamination. The H2O2 generator is placed on the rear floor. The incubator fan gently circulates vapourized H2O2 during the vaporization phase, decontaminating all interior surfaces. Following the vaporization cycle the UV lamp reduces H2O2 to trace decontaminated water. Incubator configured for decontamination. Generator receptacle is built-in and capped when not in use. Decontamination Cycle The H2O2 decontamination cycle is monitored for safety and cycle status. A physical interlock and neutralization...

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MCO19-AIC/M Incubators-6

H 2O 2 and Ultraviolet Light: The Fastest Combination The H2O2 decontamination process permits quick turn-around of the cell culture incubator from process to process where a complete decontamination is required. Applications include in vitro fertilization, tissue regeneration and other highly specific protocols subject to intense scrutiny or regulation. A secure environment for delicate cells The H2O2 incubator decontamination system in vitro is an extension of the Panasonic Active Background Contamination Control technique introduced by Panasonic in 2001. Now part of the MCO-19 incubator series,...

 Open the catalog to page 6
MCO19-AIC/M Incubators-7

The Panasonic MCO-19AIC CO2 Incubator and MCO-19M Multigas incubator are designed for demanding and regulated applications in the biomedical, pharmaceutical, medical research and clinical laboratory. Representing years of research, development and component testing, the MCO-19AIC and MCO-19M offer outstanding performance and advanced, multi-level contamination control to provide the ideal solution for cell culture protocols. High Heat Models Panasonic Benefit Minimal planning required. Entire process can be completed in lessthan three hours. Significant downtime expected. Process can take up...

 Open the catalog to page 7
MCO19-AIC/M Incubators-8

Active Background Contamination Control Panasonic’s Active Background Contamination Control combines narrow bandwidth, ozone-free ultraviolet light and InCu saFe® copper-enriched stainless steel alloy interior to fight contamination whilst the incubator remains in use. The MCO-19AIC is ideal for critical applications where continuous contamination control is essential to cell viability. The incubator offers significant economic benefits by minimising interruptions for decontamination, by improving cell culture growth and expression under stable, repeatable conditions, and by minimising the potential...

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MCO19-AIC/M Incubators-9

Intelligent Control Interface Intelligent Control Interface with Integrated LCD Display The MCO-19 series incubators are managed by an integrated microprocessor controller with graphical LCD to simplify all incubator functions. The PID controller supervises the incubator’s advanced systems to provide stable CO2, O2, temperature and humidity conditions complete with alarm, programming, calibration and diagnostic protocols. l A multi-function, high resolution LCD displays set-points, actual performance and incubator status at-a-glance. An intuitive Pop-up menu and function keys provide straight-forward...

 Open the catalog to page 9
MCO19-AIC/M Incubators-10

Precise Control of Culture Environment The MCO-19AIC and MCO-19M offer the most stable cell culture environment with outstanding control and recovery performance of temperature, CO2 and O2 concentration. Dual Wavelength Infrared CO2 Control System The Panasonic single beam, dual detector infrared CO2 sensing system offers unprecedented control accuracy and stability by simultaneously measuring sample and reference wavelengths for continuous auto-zero calibration. The ceramic-based sensor is unaffected by moderate changes in temperature and relative humidity and is linked to the sophisticated...

 Open the catalog to page 10
MCO19-AIC/M Incubators-11

Direct Heat and Air Jacket Heating System The patented Direct Heat and Air Jacket provides precise and uniform temperature control. Uniform temperatures are further enhanced by gentle fan circulation. Elevated Humidity, Low Water Level Warning To avoid cell culture desiccation, the MCO-19AIC maintains 95% RH at 37°C. l The direct heating provides highly responsive temperature control in response to door openings and the surrounding air jacket ensures uniform heating of the incubator eliminating ‘cold-spots’ and preventing condensation. l l The microprocessor provides PID control of the three...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.