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CO2 / Multigas Cell Culture Incubators

CO2 / Multigas Cell Culture Incubators
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CO2 / Multigas Cell Culture Incubators

Product catalog summary
Overview
The document details Panasonic's MCO-19AIC and MCO-19M CO2 and Multigas Cell Culture Incubators, highlighting their suitability for research, clinical, and regulated applications. These incubators provide advanced contamination control and a rapid decontamination process, making them ideal for high-value cell culture protocols.
Decontamination Features
The incubators offer a unique H2O2 decontamination option that minimizes downtime to under three hours, decontaminating all interior components and gas sampling loops without removal. The SafeCell UV system treats interior airflow to eliminate airborne contaminants, while InCu saFe® copper-enriched stainless steel surfaces provide ongoing germicidal protection.
Control and Monitoring
Equipped with a multi-function LCD, the incubators allow for programming set-points, alarms, and controller functions. They ensure stable CO2, O2, temperature, and humidity conditions through precise PID control logic. Multi-point data logging and an optional PC interface support GMP/GLP protocols.
Applications
The MCO-19AIC and MCO-19M are designed for applications such as stem cell research, tissue regeneration, in vitro fertilization, genomic and proteomic expression, and hypersensitive cell culture.
CO2 and O2 Control
The incubators utilize a proprietary single-beam, dual detector infrared CO2 sensor for precise control and rapid recovery. The MCO-19M model includes a zirconia O2 sensor for fast O2 level control.
Temperature and Humidity Control
The Direct Heat and Air Jacket conditioning system regulates temperature through multiple heating zones. The humidity pan is easy to fill and clean, with an automatic optical sensor for low water level alerts.
Cabinet Design
With a 170-litre capacity, the incubators are stackable and feature field-reversible doors. Interior components and shelves are designed for easy access.
H2O2 Decontamination Process
The H2O2 decontamination process includes a seven-minute vaporization cycle followed by a 90-minute UV lamp cycle, ensuring total decontamination and operator safety.
Comparison with High Heat Models
The H2O2 system offers advantages over high heat sterilization, such as reduced downtime and no need for component removal, allowing frequent decontamination with validation for high-value GMP protocols.
SafeCell UV System
The SafeCell UV system includes a programmable UV lamp that decontaminates air and water without affecting cell cultures, inhibiting the growth of various contaminants and operating automatically after door openings.
InCu saFe® Construction
The incubators feature InCu saFe® copper-enriched stainless steel interiors for passive germicidal protection, with easily removable components for cleaning and maintenance.
Decontamination Cycle
The non-adjustable H2O2 decontamination cycle ensures operator safety, with repositionable interior components for in situ decontamination.
Mycoplasma Survival Results
A chart demonstrates the germicidal properties of the InCu saFe® copper-enriched stainless steel alloy against four strains of mycoplasma.
Intelligent Control Interface
The high-resolution LCD display facilitates easy monitoring and programming, supporting multi-point data logging and remote alarm connections.
CO2 and O2 Control Systems
The dual wavelength infrared CO2 control system ensures accurate CO2 levels, while the MCO-19M series offers precise O2 control with a zirconia oxygen sensor.
Heating System
The Direct Heat and Air Jacket Heating System provides uniform temperature control, preventing condensation and maintaining temperature uniformity.
Specifications
The document includes detailed specifications for the MCO-19AIC and MCO-19M models, certified as Class IIa Medical Devices in the EU.
Design and Usability
The incubators are stackable with reversible doors for ergonomic use, featuring a door-mounted control panel and adjustable shelves made from InCu saFe® alloy.
Options and Accessories
Available options include decontamination kits, SafeCell UV systems, and automatic CO2 cylinder changeover systems.
Product Specifications and Components
Includes details on the roller base, InCu saFe® shelf and brackets, and half tray system, along with communication interfaces and additional requirements.
Contact Information
Contact details for the UK, Head, and France offices are provided, along with certifications for quality and environmental management systems.
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Catalog excerpts

CO2 / Multigas Cell Culture Incubators-1

CO2 / Multigas Cell Culture Incubators MCO-19AIC / MCO-19M A secure environment for delicate cells The industry’s most complete cell culture solution for research, clinical and regulated applications. Securing samples, changing lives Now with safe, effective and documented three-hour in situ H2O2 decontamination option for fastest turn- around and maximum availability.

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CO2 / Multigas Cell Culture Incubators-2

Ideal for Regulated or Sensitive Applications Advanced performance and design allows the MCO-19AIC and MCO-19M to be used with These include: confidence in high-value cell protocols among l l Genomic and proteomic expression Esoteric plant and amphibian cell culture Hypersensitive and transgenic cell culture l decontamination between processes. l l or protocols that require a strict isolation and In vitro fertilization l contamination, ultra-sensitive media and reagents, Autologous tissue regeneration & regenerative medicine l hard-to-grow cell lines, cells highly sensitive to Stem cell research...

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CO2 / Multigas Cell Culture Incubators-3

The Panasonic MCO-19AIC CO2 Incubator and MCO-19M Multigas incubator are designed for demanding and regulated applications in the biomedical, pharmaceutical, medical research and clinical laboratory. Representing years of research, development and component testing, the MCO-19AIC and MCO-19M offer outstanding performance and advanced, multi-level contamination control to provide the ideal solution for cell culture protocols. Model MCO-19AIC(UV) MCO-19AIC MCO-19M Optional Optional Optional (also requires SafeCell UV) (also requires SafeCell UV) Optional Optional InCu saFe® Copper Enriched Stainless...

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CO2 / Multigas Cell Culture Incubators-4

Decontamination Continuous Active Background Contamination Control fights contamination while cell culture protocols are in process without downtime or compromise to the incubator’s performance. The patented SafeCell UV treats interior airflow to destroy airborne and humidity pan contaminants and InCu saFe® copper-enriched stainless steel interior surfaces assure constant germicidal protection. When total chamber decontamination with verification is required, the unique H2O2 decontamination option limits downtime to less than three hours. Hydrogen Peroxide Vapour Decontamination The use of low...

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CO2 / Multigas Cell Culture Incubators-5

Incubator configured for decontamination sequence. Interior components are reoriented for in situ decontamination. The H202 generator is placed on the rear floor. The Incubator fan gently circulates vapourized H202 during the vaporization phase, decontaminating all Interior surfaces. Following the vaporization cycle the UVIamp reduces H202 to trace decontaminated water. Incubator configured for decontamination. Generator receptacle is built-in and capped when not in use. Decontamination Cycle The H202 decontamination cycle is monitored for safety and cycle status. A physical interlock and neutralization...

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CO2 / Multigas Cell Culture Incubators-6

H202 and Ultraviolet Light: The Fastest Combination The H202 decontamination process permits quick turn-around of the cell culture incubator from process to process where a complete decontamination is required. Applications include in vitro fertilization, tissue regeneration and other highly specific protocols subject to intense scrutiny or : he H2^'2 incubala deraT.iimiralior system :i v 11 -:.:■ is an extension of the Panasonic Active Background Contamination Control technique introduced by Panasonic in 2001. Now part of the MCO-19 incubator series, the cell culture C02 incubator employs ar...

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CO2 / Multigas Cell Culture Incubators-7

The Panasonic MCO-19AIC CO2 Incubator and MCO-19M Multigas incubator are designed for demanding and regulated applications in the biomedical, pharmaceutical, medical research and clinical laboratory. Representing years of research, development and component testing, the MCO-19AIC and MCO-19M offer outstanding performance and advanced, multi-level contamination control to provide the ideal solution for cell culture protocols. Panasonic MCO-19AIC / 19M High Heat Models Panasonic Benefit Speed Minimal planning required. Entire process can be completed in lessthan three hours. Significant downtime...

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CO2 / Multigas Cell Culture Incubators-8

Active Background Contamination Control Panasonic’s Active Background Contamination Control combines narrow bandwidth, ozone-free ultraviolet light and InCu saFe® copper-enriched stainless steel alloy interior to fight contamination whilst the incubator remains in use. The MCO-19AIC is ideal for critical applications where continuous contamination control is essential to cell viability. The incubator offers significant economic benefits by minimising interruptions for decontamination, by improving cell culture growth and expression under stable, repeatable conditions, and by minimising the potential...

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CO2 / Multigas Cell Culture Incubators-9

Intelligent Control Interface Intelligent Control Interface with Integrated LCD Display The MCO-19 series incubators are managed by an integrated microprocessor controller with graphical LCD to simplify all incubator functions. The PID controller supervises the incubator’s advanced systems to provide stable CO2, O2, temperature and humidity conditions complete with alarm, programming, calibration and diagnostic protocols. l l l l A multi-function, high resolution LCD displays set-points, actual performance and incubator status at-a-glance. An intuitive Pop-up menu and function keys provide straight-forward...

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CO2 / Multigas Cell Culture Incubators-10

Precise Control of Culture Environment The MCO-19AIC and MCO-19M offer the most stable cell culture environment with outstanding control and recovery performance of temperature, C02 and 02 concentration. dual zirconia Dual Wavelength Infrared C02 Control System The Panasonic singlo beam dea: detector infrared C02 sensing system offers unprecedented control accuracy and stability by simultaneous y ■■neasuing sample and reference wavelengths for corthL.OL.s aclo-ze-ro calibration. The ceramic-based se-isoi is uiaflected by moderate changes in temperature and relative humidity and is linked to the...

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CO2 / Multigas Cell Culture Incubators-11

Direct Heat and Air Jacket Heating System The patented Direct Heat and Air Jacket provides precise and uniform temperature control. Uniform temperatures are further enhanced by gentle fan circulation. Elevated Humidity, Low Water Level Warning To avoid cell culture desiccation, the MCO-19AIC maintains 95% RH at 37°C. l The direct heating provides highly responsive temperature control in response to door openings and the surrounding air jacket ensures uniform heating of the incubator eliminating ‘cold-spots’ and preventing condensation. l l l l The microprocessor provides PID control of the three...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.