PTZ 100 and PTZ 300 Single and Triple Station Tablet Disintegration Test Instrument PTZ 100 is a single station tablet disintegration test instrument. PTZ 300 is the triple station version. Both instruments are manufactured in compliance to the USP <701/2040>, EP <2.9.1/2.9.2.1> and JP Pharmacopoeias. The instruments feature a method and user management system as well as an integrated report printer. Tablet disintegration testing instruments are widely used in the pharmaceutical industry to evaluate the disintegration characteristics of formulations and the quality control of different dosage forms. All Pharma Test tablet and capsule disintegration testers are fully compliant with the current USP and EP Pharmacopeia and support both A-type and B-type baskets for regular or larger samples. They Pharma Test Apparatebau AG Siemensstr. 5 63512 HAINBURG GERMANY T: +49 6182 9532-600 F: +49 6182 9532-650 [email protected] www.pharma-test.com THE PHARMA TEST GROUP

PTZ 100/300 – Tablet Disintegration Test Instruments feature a stainless-steel housing, to be more GMP compliant than painted housing designs. Often these instruments are used in QC and IPC laboratories where most of the other equipment uses stainless steel as well. This way the Pharma Test instruments certainly do not look out of place. The disintegration basket which holds the glass tubes and discs, is placed into a metal holder and held by a magnet. The instrument detects if a basket is inserted or not. The illuminated LC-display shows status information, like the elapsed testing time. The...

PTZ 100/300 – Tablet Disintegration Test Instruments User Interface with Click Wheel Navigation PTZ 100 and PTZ 300 are operated by using a click wheel to navigate menus on the LCD screen and by functional keys to shortcut frequent operations. The display is backlit in changing colors that show the instrument status in a familiar traffic light system (green, yellow, red). Navigating the menu is quick and simple. The color-changing display makes it easy for the user to see when his input is required to proceed. The instruments have a method and a user management system. Methods can be programmed,...

PTZ 100/300 – Tablet Disintegration Test Instruments Date Storage and Export A USB flash drive can be connected to the instrument to save and load methods in .csvformat. Printouts can be stored as text files. Results can be transmitted to external systems such as LIMS via a serial interface. Furthermore, instrument firmware updates can be installed, and factory settings be restored by using the flash drive without the need for any PC or programming tool. PT-Node Network Adapter for Printing and Data Transfer PT-Node is an adapter that connects up to two Pharma Test instruments simultaneously...

PTZ 100/300 – Tablet Disintegration Test Instruments Graphical LCD screen showing actual and target settings Integrated protocol printer reduces bench space requirements Result report includes disintegration time, actual temperature and number of persisting samples Password protected access through user management system Programmable qualification interval timer reminds the user to perform instrument calibration Dedicated calibration programs and reports Copy methods between instruments by using a common USB flash drive Export test reports as text files Transmit test result to external systems...

PTZ 100/300 – Tablet Disintegration Test Instruments Standard Scope of Supply PTF 100 and PTF 300 come ready to use with the following standard scope of supply: » One “A”-type disintegration baskets for each testing station » One set of six glass tubes for each disintegration basket » One set of six disintegration disks for each disintegration basket » One flat bottom disintegration vessel for each testing station » One temperature probe » One bottle of ALGEX Magenta water preservative » Comprehensive documentation included (PDF, hardcopies optional): o User manual o DQ/QC instrument compliance...

PTZ 100/300 – Tablet Disintegration Test Instruments Example Test Report TEST REPORT - Department: Device-ID: Device: SN: Version: Date: Time: User: Method: Product: Batch: Analysis-ID: Medium: max.Time: Nom.Temp: Basket: Volume: Disk: Max. persisting: Total Runs: Customer department Customer device-ID Instrument model name Instrument serial number Instrument firmware version Date of test start Time of test start User performing test Method name Product name Batch number for each test Analysis ID (automatically ascending) Medium used for test Maximum test time Nominal test temperature Basket...

PTZ 100/300 – Tablet Disintegration Test Instruments Technical Specifications Parameter Number of testing stations Stroke height Stroke frequency Stroke accuracy Temperature range Temperature accuracy Safety systems Pressure switch to detect liquid flow to protect from overheating; thermal switch and thermal fuse to protect the heating system in case of electronical fault Testing time Adjustable from 00:00:01 to 99:59:59 (hh:mm:ss) Method management Up to 256 test descriptions (methods) can be stored on the instrument User management Up to 32 users with selectable user right levels can be stored...