PHARMA TECHNOLOGY Accelerate your Real Time Release Testing (RTRT) ■ FAST. PRECISE. ROBUST. The CU-120 CQA (Critical Quality Attributes) Analyser is an innovative in-line solution designed to ensure the quality of every individual tablet by combining the measurement of CQAs in a single system. By automating content uniformity, water content and assay testing at high speed up to 120,000 tablets per hour the system delivers timely, reliable results directly within the manufacturing workflow. This enables earlier detection of process deviations, reduces reliance on delayed laboratory testing, and supports faster, better informed, real-time process decisions. By bringing comprehensive quality monitoring directly into the production process, the CU-120 CQA Analyser helps manufacturers move from delayed quality assessment to continuous, data-driven quality control. INIR-SRS AND 3D MICROWAVE: TWO POWERFUL TOOLS TO ACHIEVE REAL-TIME RELEASE During the process, each product is individually inspected using a multipoint NIR-SRS probe (Near-Infrared Spatially Resolved Spectroscopy) to predict the API fraction, while a 3D microwave resonator measures the mass of each object. NIR-SRS allows to achieve a continuous real-time quality monitoring and a non-destructive control of tablets even with challenging dimensions/15 The CU-120 CQA analyser is designed to provide highly accurate content uniformity predictions and to identify and automatically reject non-compliant products. By enabling 100% product inspection, it supports real-time, data-driven quality decisions and contributes to a real-time release strategy.'25 (1) De Beer et al. : The application of Near-Infrared Spatially Resolved Spectroscopy in scope of achieving continuous real-time quality monitoring and control of tablets with challenging dimensions. (2) Krumme et al.: Towards real-time release of pharmaceutical tablets: 100% in-line control via near-infrared spatially resolved spectroscopy and 3D microwave resonance technology. Whatever your testing requirements, the CU -120 delivers the same Level of accuracy when analysing anything from a single tablet to high volume production at up to 120,000 tablets per hour. Low volume tablet testing Large voLume tablet testing Discover more

I SEAMLESS IMPLEMENTATION IN YOUR EXISTING MANUFACTURING PROCESS Thanks to OPC UA connectivity and the flexibility of our machine, integration into an existing manufacturing Line is straight forward and can be tailored to the specific type of production line. Operating according to the Quality by Design (QbD) principle, our analysers can transmit real-time data to upstream process steps, helping maintain the process within the defined design space specifications. Ensuring precision and process robustness ■ Object positioning & orientation check ■ Object geometry check ■ Object thickness control...

■ KEY BENEFITS Delivers accurate and reliable PAT data to enable rapid, data-driven real-time decisions (RTD). Ensures strong data integrity and regulatory compliance Supports the pathway toward Real-Time Release (RTR) One machine fits all the control strategies -Thanks to the muLtiple CQAs measured in realtime Broad range sample rate i%-ioo%, thanks to the capability to work with one tablet or with 120.000 tabs/hr Strengthens Quality Control through continuous and consistent measurements Versatile platform & technology-agnostic meeting all Control strategy requirements Minimizes material waste...