DLW Option Prep and Load Platform DLW – Fast and Clean LC/MS Loading High Throughput Screening Environmental, Food Safety, Forensics Preclinical Research, Metabolomics Drug Metabolism, Pharmacokinetics Protein Biomarker Discovery

DLW Upgrade kit including Syringe set, Pump and Wash Station Near Zero Carryover – Fast Cycles and exceptional reproducibility Wetted parts material: Stainless steel, PEEK Syringe Size: Today’s Mass Spectrometers are so sensitive that carryover becomes an issue again. To meet today’s requirements for fast, clean and reproducible LC/MS injection; CTC developed the DLW Option for the PAL system (Dynamic Load and Wash). Reproducibility (partial loop): better than 1 % RSD (under specific conditions) Carry over: Typically less than 0.003% (30ppm) Typical Clean Cycle Time: less than 1 Minute (Fast...

These tests show the excellent performance of the DLW in both UV and MS mode. Carryover Test UV: Less than 30ppm carryover (Chlorhexidine) Chlorhexidin O.emp'ml Conditions for UV carryover test Injection: Full Loop 2^1 (PEEK) Injection of 1200 ng Chlorhexidine on column; followed by 2 blank injections using the new DLW option. Less than 0.003% (30ppm) of carryover could be detected. Carryover Test MS: No Carryover detected (Dextromethorphan) Carryover: Undetectable Blank after sample injection Conditions for MS carryover test Injection: Full Loop 2\i\ Eluent Isocratic: Injection of 272 .2 pg...

Wash Station Syringe Solenoid / Actuator Valve Pump & Solvent 2 Holding Loop Spring loaded needle guide Holding Loop needle

Dynamic load and Wash Cycle principle minutes Old Syringe DLW Standard Fast DLW Download pdf Standard Cycle Fast Cycle Stator Wash Cycle www.palsystem.com 4 minutes 67 seconds 51 seconds Pump 2 Solenoid / Actuator Valve Holding Loop Rear air gap Wash Station Sample Front volume Sample Loop Column Waste DLW Standard Cycle cycle start DLW Fast Cycle cycle start 1. aspirate rear air segment 1. aspirate rear air segment 2. get sample aspirate rear, inject and front volume. 2. get sample aspirate rear, inject and front volume. 3. aspirate front air segment 3. aspirate front air segment 4. passive...

SYSTEM LC/LC-MS General Specifications Ordering details System Type XYZ robot with injection unit PAL DLW-2 Option Dynamic Load an Wash Option for fast and clean LC Cycles 1pc DLW-2 injection adapter with sample holding loop and syringe 100µl 1pc wash station 1pc wash solvent pump station with 2 active micro pumps 2 pc 1 liter wash solvent bottles 2 pc solvent bottle transfer line including solvent filter 1 pc system CD ROM DLW for xt-Systems 1 pc manual DLW Option requires but does not include xt-Upgrade for PAL and Firmware 4.1.X or higher Choose this kit if your PAL is already equipped with...

Clean and efficient removal of carryover in the entire flow path Holding loop for effective rinsing of the complete sample path Integrated pumps for active wash solvent delivery selectable wash time for organic and aqueous solvents Spring loaded syringe needle positioning in needle guide – no dead volume Existing PAL Systems can be upgraded X-Type Syringe based SYSTEM www.palsystem.com