DLW Option Prep and Load Platfor DLW-Fastand Clean LC/MS Loading High Throughput Screening Environmental, Food Safety, Forensics Predinical Research, Meabolomics Drug Metabolism, Pharmacokinetics Protein Biomarker Discovery

?/IL HTC xf :;i',V JtwJe kl induding Swire an. pump dr :1 Wash S箮lon Spcifications DIW Option Near Zro Carryover - Fast Cycles and exceptional reprodudbility Toda/s Mass Spectrometers are so sensftve that canywer be<omes an issue again. To meet today's requiremenls for fast, clean and reprodudWe LQMS injection; CTC developed tbe DIW Option for the ML System (Dynamic Load and Wash). Now tfie sample is no longer in contact with the ^ringe but it B aspirated into a holding loop. The syringe onty ads as an aspirator and dispenser device in order to exactly measure the amount of sample vrfiidi needs...

Carryover Results UV and MS Thse tests shcw the excellent performance of the DLW in both UV and MS mode Carryover Test UV: Less than 30ppm carryover (Chlorhexidine) 200t3t1 2.50 3JS 1:j OxxJttJor^ for UV carrvovff t说t Column: Halo 0& 2.1x50mm, 28 Ro#: o.Vnymin Injection: Fui Loop 2(il(PEEK) Elueffl: A:H20+omlA/ BAcrtorrtrrte*(l^IﯯA Gradent 10%B (OS min) - W to 90*B(75fflin>- 90*B(l mfi) Wa*1: HO + 0,1*bTFA Waste AcdOntnle + O.l^TTA injertrcn of 1203 ng Chlcrtie&dine on tdurm; fdlcwed bf 7 btank injections usng the new DIW opbon. Less Sun 0.003% (Jppm) of unyover ﻜutd be dtecte). Carryover Test...

Wash Station Syringe Solenoid/ Acluator Vah/e PumpS Suivent PumpS Solvent 2 Holding Loop Spring loaded needle guide Holding Loap needle

Dynamic load and Wash Cycle principle rrifim 3 ! t 3 4 1 1 1 1 1 1 1 1 1 1 1 1 5B- 4 niman Il MCMtds 1 I 1 Dcwnload pdt Standard Cycle Fast Cyde Slator Wash Cycle wrtvpalsystemxom Wash Soient 1 Wash Solvenl 2 c=f> Pump l Pump2 Solcnoid / Actuatot Valve Q Holding Loop Wash Station Rear air gap Sample Loop Column Wash 2 Wash ' Front air gap Waste Pump DLW Standard Cyde cycle start 1. aspirale rear air segment Z get sample aspirale rear, inject and front volume, 3. aspirale front air segment 4. passive needle clean outstde in wash position i 5* dispense front air segment and frcot sample volume...

JJ^LSYSTEM LC/LC-MS General Spcifications System Type XYZ robot with injection unit Local User interface Control panel wth 4 funcbon keys, graphical LCD dispLy, unique scroll knob (or teadi fonctions Ranote Control Cycle Composer control software Windews 2000 / XP Third parTy instrument drWrs for major LC/LC- MS Systems Maintenance At鯜ssiblrty lo ail maintenance pans trom front Praentatwe maintman kits availabie Eledrical Contre* ix RS232/11 LAN (with optional ML*/ EledronKs) 3xTTL tnput 2xOpo Coller Inpui 2x Rela/Output Power Requirements 100-24W, 12OT.50/60HZ Environment 4°C - 4(TC constant...

Ciean and efficient removal of carryover in the entire flow path Օ Holding loop for effective rinsing of the complte sample path Integrated pumps for active wash solvent delivery selectable wash time for organic and aqueous sofvents 蕕 Spring loaded syringe needle positioning in needle guide - no dead volume Existing RAL Systems can be upgraded Օ X-Type Syringe based