Semi-automatic isolator fillers There is a growing demand for cold aseptic filling equipment for nutraceuticals, functional beverages, and pharmaceutical alternatives on a laboratory scale. Suitable for both the food and pharma markets, the FS213 & FS214 aseptic filling cabinet combines SIP and chemical sterilization using both the isolator principle and a down flow of sterile air. By automating the chemical sterilization of the outer surface of the bottles, risks of contamination when transferring the bottles into the filling are eliminated. A bottle transfer cabinet connected to the filling cabinet enables the use of various sizes & styles of packaging. During production both cabinets are fully conditioned to prevent operational errors. The semi-automated un-capping, filling and closing option, facilitates accurate volume dosing at line capacities up to lOOL/hr. The FS214 is configured with 2 filling points, allowing glove access by 2 operators. The sterility of the machines has been validated according the ISO 11138 standard. This means that this packaging station has been proven to meet the highest standards for aseptic operation as required in the pharma and food industries. Consequently, this unique cabinet is suitable for filling a large number of sterile samples for any application, regardless of the pH-level. Features & Benefits • Sterile Isolation: A positive pressure filling chamber with sterile air downflow prevents contamination. • Validated Sterility: Meets ISO 11138 standards for reliable disinfection and sterility assurance. • Traceability: Critical Control Point monitoring with data logging of SIP cycle for traceability & quality control • Automated Decontamination: H202 or PAA fogging system eliminates manual cleaning risks. • Semi-Automated Filling: Integrated un-capping & capping devices enable efficient filling • Precision Control: Automated volume dosing ensures consistent accuracy for every sample. Working Principle • Dairy & plant based alternatives • Tube feeding formulation • Functional beverages The OMVE Asepto-Fill® consists of 3 interconnected cabinets: the packaging cabinet, the main filling cabinet, and an outlet box. The packaging cabinet is sterilized by a fogging system or connected with a pre-sterilized bag with packaging (depends on the execution). The main filling cabinet is pre-sterilized via an automated fogging cycle and a SIP procedure for the connected filling lines. Both the packaging cabinet and outlet box are operated as hygienic locks. This allows loading and unloading of packaging materials into the main cabinet while maintaining process sterility. The filling points in the main cabinet have CIP and SIP capabilities.

• Different closing devices for PET packaging • Nitrogen jet for lower oxygen in the packaging • Heat sealer (non-aseptic) OMVE Americas Inc. Milton, Canada Tel +1 416 986 8442 De Meern, The Netherlands Tel +31 30 241 00 70 [email protected] Disclaimer: no rights can be derived from the content in this brochure. Version 1/2025