nSight™ DeepSee ULTRAFAST LASER SYSTEM FOR MULTIPH 0T0N IMAGING The InSight DeepSee Advantage • Broadest tuning range: 680 nm to 1300 nm for deepest imaging • Short pulse width and highest peak power for maximum fluorescence • Integrated DeepSee™ to deliver short pulses to the sample • Ideal beam characteristics optimized for multiphoton imaging • Fully automated, turn-key system • Dual wavelength option for uncaging, CARS and multi-modal imaging Multiphoton microscopy Multimodal imaging including CARS and SHG Time-resolved photoluminescence Non-linear spectroscopy Optical computed tomography Surface second harmonic generation Terahertz imaging Semiconductor metrology A Newport Corporation Brand Spectra-Physics introduces InSight™ DeepSee™, an extraordinary new ultrafast laser system that takes multiphoton imaging to new depths. Based on patented technology1, the new InSight DeepSee delivers nearly double the tuning range of existing ultrafast lasers and provides seamless access to long infrared wavelengths for deepest in vivo imaging. Robust and fully automated, InSight DeepSee provides easy-to-use, hands-off operation, freeing users to focus on their critical research. InSight DeepSee features an unprecedented 680 nm to 1300 nm continuous tuning from a single source, short 100 fs pulse widths and highest peak power levels into the infrared where imaging penetration depth is maximized. Spectra-Physics' integrated patented DeepSee, the industry standard dispersion pre-compensator, delivers the short pulses through a microscope to the sample for maximum fluorescence. InSight DeepSee also has exceptional beam pointing stability, beam quality and output power stability, making it ideal for microscopy A dual wavelength option with a second output beam complementing the main tunable output is available for advanced imaging techniques including uncaging, CARS imaging and multimodal imaging. This fully automated ultrafast laser can be seamlessly tuned with the click of a mouse to any wavelength within seconds at speeds over 50 nm/sec. InSight DeepSee is designed, built and tested to our highest quality standards for reliable hands-free operation. Typical Tuning Curve and Pulse Width 1. The automated dispersion compensation technology in this product is protected by US patent number 7,962,046 CV> Newport. Family of Brands - ILX Lightwave8 • New Focus™ • Ophir* • Oriel8 Instruments • Richardson Gratings™ • Spectra-Physics8 • Spiricon*

InSight™ DeepSee Output Characteristics Tuning Range Repetition Rate Beam Divergence, full angle4 Beam Pointing Stability Tuning Speed Environmental Requirements Temperature, Operating Relative Humidity, Operating InSight DeepSee <350 urad full range >50 nm/sec full range Temperature, Storage Relative Humidity, Storage Cooled Water Temperature in Closed-loop Chiller InSight DeepSee Dimensions InSight DwpSee -Dual Option Outpul —Main Tunable Outpul Back View 1. Due to our continous improvement program, specifications may change without notice 2. Specifications only apply to the wavelength noted...