Group: NETZSCH
Catalog excerpts
Agitator Bead Mill DeltaVita® Agitator Bead Mills for Your Pharmaceutical Applications a Business Field of NETZSCH Grinding & Dispersi
Open the catalog to page 1NETZSCH DeltaVita® Agitator Bead Mills for Your Pharmaceutical Applications Pharmaceutical manufacturing processes require the utmost care and precision - from initial laboratory testing to full-scale production. In this tightly regulated industry, special machines are required that facilitate production in accordance with Good Manufacturing Practice (GMP) guidelines through every step of the process. NETZSCH understands and respects the special requirements and highly confidential nature of pharmaceutical applications. When working with high-quality, high-cost materials, there is no room...
Open the catalog to page 2Advantages of Grinding Active Ingredients More than 90% of drugs approved since 1995 exhibit poor solubility, poor permeability, or both. More than 40% of the newly-discovered active ingredients also display poor to very poor water solubility, which is a serious challenge for the successful development and marketing of new drugs in the pharmaceutical industry. Most of the New Chemical Entities (NCE) are not considered for pre-clinical studies due to the formulation hurdles presented by drugs that are not readily soluble in water. With the increased particle surface area associated with...
Open the catalog to page 4DeltaVita® Technology The NETZSCH-engineered DeltaVita® mills are based on the proven Zeta® mill technology. Thanks to the high level of energy efficiency, high throughput rates and multi-pass or circulation modes of operation, it is possible to achieve high-quality stable, homogeneous dispersions with excellent reproducibility. This superior technology prevents excessive heating of the product. The unique grinding media separation system impedes blockage of the screen at the outlet of the mill and guarantees reliable operation. Among other impressive features, the DeltaVita® line offers...
Open the catalog to page 5NETZSCH DeltaVita® Agitator Bead Mills for the Laboratory and Pilot Plant DeltaVita® 15 - 300 R&D in small batches is an essential part of the process when developing new drugs. The market demands the ability to confirm process feasibility without wasting scarce, costly materials. NETZSCH provides the solution. The laboratory machines from NETZSCH are ideal for testing where only the smallest batch sizes are needed to achieve significant test results with minimal product loss within a short period of time. The laboratory agitator bead mills from NETZSCH offer: Repeatable results - batch...
Open the catalog to page 6The DeltaVita® 600 is a machine for batch sizes from 1 liter to 6 liters to support the clinical trial trials, or small scale production. Features ■ Interchangeable grinding chamber designs ■ Optional explosion-proof design for installation in hazardous areas ■ PLC control with optional interface for data acquisition Optional CIP and SIP function ■ Available with 100 ml and 200 ml grinding systems Grinding chamber volume ml Drive power Speed range Batch size (min - max) Grinding media diameter with batch mode components
Open the catalog to page 7The DeltaVita® product line can be scaled up from the DeltaVita® 300 to full- scale production models up to 4 000 liters. The production systems are available in two frame designs. The flexible portable design is a complete machine located within the process suite. The fixed installation option is a split frame design with all mechanical components outside the clean room and only the wetted components in the process suite. Technical data Grinding chamber volume Drive power Speed range Batch size (min - max) Grinding media diameter Delta Vita ® Delta Vita ®
Open the catalog to page 8Materials & Surface Finish Stainless steel with moderate surface finish roughness of Ra = 0.4 µm High-tech and high-strength ceramic materials for metal-free processing NETZSCH-Ceram Z NETZSCH-Ceram N NETZSCH-Ceram C All product-wetted parts can be sterilized with SIP or autoclave (depending on machine size) Food / pharmaceutical grade elastomers and lubricants Fully CIP and SIP capable PLC control Optional data acquisition and process parameter set-point management Double-acting mechanical seal Choice of grinding chamber materials Batch sizes from 4 liters to 4 000 l
Open the catalog to page 9NETZSCH-Beads® NETZSCH-Beads® – Always the Right Choice! The selection of suitable grinding media represents an excellent optimization feature in dispersing and wetgrinding processes with agitator mills. With the use of NETZSCH-Beads® you will achieve optimal results. Ideally compatible grinding media for NETZSCH agitator bead mills Optimum combination of machine, grinding tool and application Process optimization and performance enhancement Increased energy efficiency NETZSCH service worldwide from a single source Comprehensive test certificates (LOT -related) Ceramic Grinding Media...
Open the catalog to page 10NETZSCH Service Technical assistance must arrive quickly and work perfectly. That‘s why we offer an extraordinary range of services with the assurance that highly-qualified NETZSCH personnel perform these services all over the world. Our specialists provide quick andreliable assistance. We advise you in your own language, wherever you are. The NETZSCH service network extends to all corners of the globe. As a result, we strengthen the competitive capacity of our customers, facilitate trouble-free, efficient processes and ensure maximum machine availability. Our range of services includes...
Open the catalog to page 11NETZSCH-Feinmahltechnik GmbH Selb, Germany NETZSCH Lohnmahltechnik GmbH Bobingen, Germany NETZSCH Premier Technologies, LLC. Exton PA, USA NETZSCH Industria e Comercio de Equipamentos de Moagem Ltda. Pomerode, Brazil NETZSCH Technologies India Private Ltd. Chennai, India NETZSCH Trockenmahltechnik GmbH Hanau, Germany NETZSCH Espana, S.A.U. Terrassa/Barcelona, Spain NETZSCH Mastermix Ltd. Lichfield, Great Britain NETZSCH (Shanghai) Machinery and Instruments Co., Ltd. Shanghai, China NETZSCH FRERES S.A.R.L. Arpajon, France NETZSCH Vakumix GmbH Weyhe-Dreye, Germany AO NETZSCH Tula Tula,...
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