Group: NETZSCH
Catalog excerpts
Thermoanalytical Characterization of Pharmaceuticals NETZSCH Annual 2000 olume tion V plica The NETZSCH Annual 2000 Thermoanalytical Characterization of Pharmaceuticals (engl.) is based on decades of experience of the renowned specialists Dr. E. Marti, Solvias AG (former Novartis), Basle / Switzerland, and Prof. Dr. W.-Y. Ma, Shanghai Institute of Pharmaceutical Industry, Shanghai / P.R.C., in the fields of Pharmaceutical Research and Technology, as well as E. Kaisersberger and Dr. G. Kaiser, NETZSCH “Thermal Analysis Applications”, NETZSCH-Gerätebau GmbH, Selb / Germany. Thermoanalytical Characterization of Pharmaceuticals Selected examples of drug substances and excipients are outlined in this workbook, which is based on thermoanalytical measurements using DSC, thermobalance, TG-FTIR, TG-DSC-MS and c-DTA. Each substance is introduced by literature data and pharmaceutical use. Special attention having been paid to the presentation of easily understandable experimental results. In addition, the collected experimental facts have been evaluated by different software programs. Routines have been applied for the determination of melting points, enthalpy of fusion and crystallization, dehydration, purity, kinetic data, Gibbs free energy function, melting range and molten fraction. The importance of gas analysis by FTIR and mass spectrometry has been underlined. The results obtained with the performed investigations are brought into the context of thermodynamics, physical chemistry and solid-state or material sciences. E. Marti • E. Kaisersberger • G. Kaiser • W.-Y. Ma Authors E.Marti E. Kaisersberger G. Kaiser W.-Y. Ma Below you can have a look at the table of contents. NETZSCH-Gerätebau GmbH Wittelsbacherstraße 42 95100 Selb Germany Tel.: +49 9287 881-0 Fax: +49 9287 881 505 at@netzsch.com www.netzsch.com
Open the catalog to page 1Thermoanalytical Characterization of Pharmaceuticals Table of contents Melting point Glass transition 02. Paracetamol Polymorphism 03. Carbamazepine 05. Polyethylene Glycol 6000 06. Polyethylene Glycol 1500 07. Microwax-Paraffin 10. Vanillin Ribavirin Sulfadimidin Saccharin Phenolphthalein 11. Phenacetin p-Aminobenzoic Acid 12. Castor Oil 13. Calcium-Oxalate Monohydrate 14. a-D-Glucose 15. Estradiol Hemihydrate 16. Ranitidine Hydrochloride Thermal resistance Polymorphism Glass transition Gibbs free energy functions Stability of polymorphs Thermal stability Melting, polymorphic...
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