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Ultra low flow drugs delivery media

Ultra low flow drugs delivery media
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Control for Drug Delivery Drug Delivery Drug Delivery/Device Design and Manufacture Managing extremely low flows for the release of therapeutic agents to optimize patient outcomes. Porous Metal - A stable, biocompatible, non-reactive material that can be integrated into delivery systems and calibrated to flow various formulations as well as large and small molecules. Porous metal is ideal for providing highly dependable, repeatable flow control as well as precise diffusion and metering of fluids and drugs. This durable material can be designed to support multiple delivery modes for therapeutic agents. Flow Control/Controlled Release Powered Devices - Pumps, Patch Pumps, and Powered Delivery Systems In conventionally configured pumps or devices with a driving mechanism (battery, MEMS, spring), Mott's porous flow control elements can be designed to control flows as low as 1-2 nanoliters per minute. The components can be configured for different formulations, sizes and geometries. Liquid Flow Rate (nl/min) Sustained release Mott porous metal can provide controlled and sustained release of drugs via diffusion based on Fick's Law. Elements can be engineered to deliver a drug over an extended time frame ranging from days to many months based on reservoir size, dosing requirements, efficacy and drug half-life. Mott can also provide porous metal solutions for specific molecules and formulations. Cumulative Release of BSA Through Mott Porous @ 37°C Time (Days) Porous metal can be used to control the flow of dissimilar materials (Part A, Part B) and for mixing liquids, or gases into liquids. The torturous media flow path can optimize mixing and dwell time for dissimilar materials. In addition, Mott's flow modeling capability can help you determine the optimal configuration to control flow rate of multiple materials - with the same driving force, or with different delivery pressures for each component. mott corporation 84 Spring Lane, Farmington, CT 06032-3159

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Porous Metal - Biocompatible. Highly Inert Porous metal is available in biocompatible materials including stainless steel and titanium. Mott Corporation routinely supplies components fabricated from 316L Series stainless steel and unalloyed titanium (ASTM 1580-07); plus many common and exotic metallurgies including zirconium, molybdenum, niobium; and from precious metals including gold, silver, and palladium. Inert construction makes porous metal well suited for a wide range of chemicals and formulations used in drug delivery applications. Mott Manufacturing Capabilities Mott has over 50...

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