The World Reference Stability Analyzer by Static Multiple Light Scattering
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SHELF-LIFE & DISPERSIBILITY ANALYZERS THE WORLD REFERENCE STABILITY ANALYZER BY STATIC MULTIPLE LIGHT SCATTERING

PARTICLE CHARACTERIZATION AT ITS BEST Microtrac is your preferred partner for the comprehensive characterization of particulate systems. We provide our customers with advanced technologies to obtain consistently reliable results. Innovation and quality are at the core of everything we do. As part of Verder Scientific, we provide worldwide support through a network of subsidiaries and distributors.

Particle and Pore Size Range 1 nm THREE PILLARS OF EXCELLENCE Dynamic Light Scattering Surface & Porosity NANOTRAC Series Stability & Dispersibility BELSORP & BELPORE product lines Laser Diffraction Dynamic Image Analysis characterization of particles. Microtrac is the only worldwide ments that are ideal for particle sizing and characterization. The BELSORP and BELPORE analyzers are used for the deter- supplier of dynamic image analysis, static image analysis, laser The development and production site for this product line is mination of gas and vapor adsorption amounts, as well as BET...

TURBISCAN RANGE THE WORLD LEADER IN SHELF-LIFE AND STABILITY ANALYSIS I SAVE TIME Up to 1,000 times faster compared to a conventional visual stability test I DETECT & QUANTIFY Sedimentation, phase separation, aggregation, coalescence, coagulation, creaming… All destabilizations are detected and quantified I OBJECTIVE & RELIABLE Instrumental method, no dilution, no external stress, measure the sample as is – analysis you can trust I WIDE RANGE OF APPLICATIONS Suspensions, emulsions, foams, from low to high concentrations (10-4 - 95% v/v), opaque, clear, coloured samples, from nano to macro...

STATIC MULTIPLE LIGHT SCATTERING (SMLS) CUTTING-EDGE STABILITY AND DISPERSIBILITY TECHNOLOGY COUPLED WITH SMART DATA ANALYSIS Turbiscan is based on the Static Multiple Light Scattering (SMLS) technology, the most suitable method to characterize Light source liquid dispersions, directly, in their native state. In most emulsions, suspensions and formulations the concentrations are too high to be analyzed “as is” with light scattering and their characterization requires dilution or mechanical stress, altering their state and structure. SMLS offers the ability to investigate the dispersion...

HOW DOES IT WORK SCANNING READING HEAD Moving measurement head TURBISCAN RANGE STATIC MULTIPLE LIGHT SCATTERING (SMLS) Light source mean particle size particle concentration cell radius extinction efficiency HIGH RESOLUTION TO THE SMALLEST VARIATION OF PARTICLE SIZE VARIATION AND MIGRATION Backscattering (BS) and Transmission (T) intensities are directly I Sensitive to the slightest variation of particle size SMLS consists of sending photons (NIR light source, 880nm) into the sample. related to particle size (d) and particle concentration (ϕ) and are These photons, after being scattered...

STATIC MULTIPLE LIGHT SCATTERING (SMLS) DATA REPRESENTATION DESTABILIZATION DETECTION Scans are overlayed on the same graph and in function of In the case of destabilization, deviations in scans are detected as a function of sample height. Due to the high sensitivity of the SMLS technology, sample height. Each scan has a specific colour from blue - first destabilizations are detected in their very early stage and up to 1,000 times faster than visual observation. scan to red - last scan to easily understand signal variations in function of time. Particle size increase Particle size increase

TURBISCAN SMART ANALYSIS ON-BOARD TECHNOLOGY FOR ONE-CLICK RESPONSE TURBISCAN STABILITY INDEX – TSI PARTICLE SIZE & DISTRIBUTION Turbiscan Stability Index (TSI) sums all the signal variations along the entire sample height and therefore, takes into account all destabilizations Particle size distribution is determined from migration profiles occurring. Thanks to the TSI, sample comparison is easy as the higher the TSI, the lower the stability. and migration velocities and offers to investigate size and its distribution in native samples and without any pumping, The key points of the TSI: it...

SHELF-LIFE & DISPERSIBILITY ANALYZER TURBISCAN THE BEST TECHNOLOGY FOR FAST & NON-INVASIVE STABILITY ANALYSIS

TEMPERATURE RANGE TURBISCAN STABILITY INDEX THE WORLD REFERENCE STABILITY ANALYZER Turbiscan LAB allows fast and sensitive identification of destabilization mechanisms (creaming, sedimentation, flocculation, coalescence, …). A temperature-controlled measurement chamber allows stability monitoring at specific storage temperatures or acceleration of the destabilization process with a temperature increase up to 60 °C. Turbiscan LAB can be used in both R&D and QC labs for the development and routine control of raw materials and final product formulations. The Turbiscan technology does not only...

3-SAMPLE MACROSCOPIC & COLLOIDAL STABILITY ANALYZER FEATURES Static Multiple Light Scattering (SMLS) Technology 3 independent sample positions Temperature range: from 20 °C to 60 °C Accelerated destabilization detection up to 1,000x Turbiscan TRILAB is a multi-sample stability analyzer based on the SMLS technology. It enables fast and reliable shelf-life studies of formulations (emulsions, suspensions, foams). faster than visual observation Real stability: no dilution (10 -4 up to 95% v/v) – No mechanical stress Destabilization Quantification: migration velocity, The TRILAB offers several...

TURBISCAN TOWER 6-SAMPLE MACROSCOPIC & COLLOIDAL STABILITY ANALYZER Turbiscan TOWER is the flagship product of the Turbiscan range, of the SMLS technology, but it also enables accelerated stability for fast, precise, and quantitative stability measurement of for- tests by varying the temperature from 4 °C to 80 °C and follows mulations (emulsions, suspensions, foams). ISO recommendations (ISO/TR 13097:2013, ISO/TR 18811:2018). The stability measurement is done with a non-invasive and non-de- The TOWER offers 6 independent measurement positions allow- structive technique, preserving the...