Dynamic Light Scattering with the Nanotrac Series
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MICROTRRC WVIE3B PARTICLE CHARACTERIZATION NANOPARTICLE SIZE & ZETA POTENTIAL

PARTICLE CHARACTERIZATION AT ITS BEST Microtrac MRB is your preferred partner for the comprehensive characterization of particulate systems. We provide our customers with advanced technologies to obtain consistently reliable results. Innovation and quality form the basis of our business. As part of the Verder Scientific Group we provide worldwide support through a network of subsidiaries and distributors in every country.

THREE PILLARS OF EXCELLENCE Dynamic Image Analysis Dynamic Light Scattering Surface & Porosity NANOTRAC Series Laser Diffraction Static Image Analysis BELSORP & BELPORE product lines Microtrac MRB offers three product lines with centers of excellence on three continents. I Scattered Light Analysis: Microtrac MRB is a leading supplier of both With the CAMSIZER series Microtrac MRB Specific surface, BET value and porosity of dynamic and static light scattering systems provides high-quality systems for the powders are determined by gas adsorption. for particle size determination. The portfolio...

PARTICLE ANALYSIS DOWN TO NANOMETERS DYNAMIC LIGHT SCATTERING BY MICROTRAC MRB Microtrac MRB’s NANOTRAC product family consists of highly flexible Dynamic Light Scattering (DLS) analyzers that provide information on particle size, zeta potential, concentration and molecular weight. Microtrac MRB is a pioneer of particle size analysis and has been developing DLS systems for over 30 years. The innovative design of the NANOTRAC series allows faster measurements with reliable technology, higher precision, and better accuracy. All of this combined into compact DLS analyzers with a revolutionary...

Advantages of Microtrac MRB’s DYNAMIC LIGHT SCATTERING Measurement range from 0.3 nm to 10 μm Concentration up to 40% w/v Minimum volume of 5 μl Results in as little as 30 seconds A priori knowledge of the sample not required Easy detection of multimodal and broad distributions without any need to select or input additional information Repeatability better than 1% for 100 nm polystyrene Temperature range from 4°C to 90°C 180° backscatter DLS setup Fixed optical setup including external measurement probe Frequency Power Spectrum calculation model instead of PCS Controlled reference optical...

NANOTRAC SERIES: DLS ANALYZERS NANOTRAC SERIES 180° DYNAMIC LIGHT SCATTERING, THE MICROTRAC WAY Nanoparticles suspended in a liquid dispersion are subject to Brownian motion, which is a result of random collisions from molecules in the liquid medium. The particles’ velocity distribution, averaged over time, approaches a known functional form - their size distribution. Dynamic Light Scattering (DLS) is the technology used to calculate that size distribution, based on the particles’ measured velocity distribution. The optical bench of the NANOTRAC line is a probe containing an optical fiber...

Features Complete optical bench in a compact fiber probe Laser Amplified Detection technology Highest signal-to-noise ratio in the industry One calculation for all sample types independent of concentration or distribution shape One measurement at one angle, 180° Measures particle size, zeta potential, molecular weight, and concentration calculation provides robust calculation of all types of particle size distributions – narrow, Iterative Particle Size Calculation from Power Spectrum broad, mono- or multi-modal – with no need for a priori information for algorithm fitting as it is for PCS....

NANOTRAC FLEX FLEXIBLE IN SITU MEASUREMENTS I Most flexible DLS ever I Unique external probe design I In situ particle sizing and monitoring I Turn any vessel into a sample cell – no consumables required I External probe allows dip and measure I Universal solvent compatibility I Small footprint

The unique probe design of the NANOTRAC N A N OT R AC S E R I E S : D LS A N A LY Z E R S FLEX allows the measurement of only one droplet as shown in the top left figure. In this case only a minimum sample volume is needed. The probe also fits easily into a 1.5 mL Eppendorf Tube® (top right figure). With the NANOTRAC FLEX, every vessel can be used as a measurement vessel, and there is no need for cuvettes of any kind. This allows the use of the probe either at line or in line to monitor the particles growing during a reaction. During a reaction, the dispersion is either flowing or stirring....

NANOTRAC SERIES: DLS ANALYZERS NANOTRAC WAVE II IDEAL FOR NANOPARTICLE & ZETA POTENTIAL ANALYSIS Features © Stable fixed optics sample interface - no adjustments required © Rapid field reversal prevents electro-osmosis O Robust mobility calculation as a function of power spectrum ratio © High concentration zeta potential measurements © Sample concentration and molecular weight determination © Laser Amplified Detection - high signal to noise ratio The measurement of zeta potential in the Microtrac MRB DLS analyzers takes advantage of the same Power Spectrum methodology used for measuring...

ACCURATE MEASUREMENT OF COLLOIDAL SYSTEMS single number for total scattering that can be is a positive polarity (concentration decreasing) appropriate units such as cm3/ml or N/ml (as used to determine particle mobility in microns and a ratio greater than one is negative seen below). It is also possible to calculate the / sec / volt / cm and particle polarity as + / -, (concentration increasing) for a positively molecular weight by either the hydrodynamic charged probe surface. radius or a Debye plot. Measuring mobility and zeta potential begins Mobility = C x (ratio of [PSD(on) – PSD(off)]...

APPLICATIONS Versatility is a great strength of dynamic light scattering (DLS) analysis. This makes the method suitable for a variety of applications in both research and industry. Microtrac MRB’s NANOTRAC series was designed for convenient, easy-to-learn operation. Thanks to their robust design, the instruments are practically maintenancefree and fit for 24/7 operation. The high sample throughput and the extremely wide particle size range from 0.3 nm to 10 μm are reasons for the method’s popularity in so many laboratories. TYPICAL FIELDS OF APPLICATION PHARMACEUTICALS BEVERAGES & FOOD INKS...