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How to Optimize Your Dispensing Station


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How to Optimize Your Dispensing Station - 1

Application Note Consistent Formulation Quality Preventing Errors in the Dispensing Room Wrong measurements caused by unsuitable scales, incorrect selection of raw materials, false labeling of materials and incorrect documentation. What do these problems have in common? They are top reasons for quality problems and inefficiencies during the dispensing process. However, the correct design and set-up of a dispensing station can reduce those error sources significantly, while and at the same time, improving the workflow efficiency of the weighing tasks. This Application Note describes two weighing systems designed to ensure the highest formulation accuracy in the dispensing room. Both systems address the challenges of ensuring accurate measurements, of preventing operating errors and of fulfilling documentation requirements. However, the approach taken with the two systems differs: • he first application example shows how a tradiT tional recipe-weighing process can be enhanced to improve the quality of dispensing and facilitate documentation requirements. • he second application example examines a weighT ing system based on formulation software, which is integrated to the company's production and resource-management systems providing improvements in process automation. Contents 1 Selecting the right scales 2 Application 1: Recipe Weighing 3 Application 2: Formulation Solution 4 Summar

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How to Optimize Your Dispensing Station - 2

Consistent Formulation Quality 2 1 Selecting the right scales METTLER TOLEDO - Application The dispensing room usually includes several scales with different capacities and resolutions toweigh different amounts of materials, such as APIs and excipients. Choosing the right scales is critical to ensure each amount of raw material is weighed accurately. The right scales are chosen with consideration of measurement uncertainty, possible environmental influences and the required weighing tolerances. The scales in the following examples have been selected according to Good Weighing Practice™...

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How to Optimize Your Dispensing Station - 3

Consistent Formulation Quality Accuracy and versatility with high-precision The installations consist of two METTLER TOLEDO PBK989 bench scales and one PFK989 floor scale to weigh materials from 0.5 grams to 1,200 kilograms at the highest accuracy. The weighing platforms offer a wide weighing range, which allows for accurate measurements of small amounts into or out of heavy containers. The set-up also reduces the number of scales required in a comparable analog weighing system. That is a real benefit, considering the constrained space of dispensing stations. High-accuracy weighing...

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How to Optimize Your Dispensing Station - 4

The first weighing application describes a recipe-weighing system that is designed to provide maximum weighing process accuracy without the support of a formulation software. The floor scale and both bench scales are connected to an ICS689 weighing terminal. Depending on the dimensions of the dispensing room and the location of the scales, a second terminal might be required for the floor scale for better usability. Furthermore, a barcode reader and label printer are connected to each of the terminals to ensure accurate material selection and traceability of the dispensed materials. The...

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How to Optimize Your Dispensing Station - 5

Consistent Formulation Quality 3 Application 2: Formulation Solution The second application example describes an advanced formulation solution, which can be operated alone or fully integrated into existing manufacturing and data-management systems. All three weighing platforms are connected to a single IND890 PC weighing terminal, which can be mounted onto the wall to gain working space and facilitate easy cleaning. The large touchscreen is easy to use and read because weighing data from each of the three scales and the sum scale are displayed simultaneously. Simple icons allow for...

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How to Optimize Your Dispensing Station - 6

Consistent Formulation Quality FormWeigh.Net fulfills the technical 21 CFR Part 11 requirements needed for an in-process control system as stated by the U.S. Food and Drug Administration (FDA). All batch-relevant information is automatically recorded and verified. It also can be electronically signed; a second operator is no longer needed to fulfill the four-eye requirement. The audit-trail function ensures that notifications are sent when relevant data is changed. Additionally, all audit-relevant information modification is documented, including who did what, when and where. IND890 PC...

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