Accessories Catalogue For Perfect Freeze Drying

Accessories for Perfect Freeze Drying

Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Phone +49 (0) 55 22 50 07-0 Fax +49 (0) 55 22 50 07-12 www.martinchrist.de [email protected]

Freeze Drying / Lyophilisation 5 Drying Chambers and shelves 19 3.3.1 LSCplus sealing device (wireless) 30 3.3.2 LSCplus shelves (wireless) 33 3.4 4 4.3 Thermoblocks, split 48 4.4 Thermoblocks, not split 52 4.5 4.10 Ampoules 64 4.11 Single vial sealing device 64 4.12 Injection vials 65 5 Process Data Acquisition 91 Cooling Baths and Freezing Equipment 97

Freeze Drying / Lyophilisation Freeze drying or lyophilisation takes place in the solid (frozen) state and is the preferred means for the long-term preservation of a wide variety of substances and for specimen preparation for modern analytic methods. It is also used in animal preparations and in museums to preserve the original material forms. Relatively new applications involve the drying of nanoparticles, where it is important to avoid the effects of capillary forces and surface tension. Freeze drying is used for more than 30 different substance categories or materials, with the pharmaceutical...

1 Freeze Drying / Lyophilisation

Freeze Drying / Lyophilisation Freeze Drying / Lyophilisation Freeze drying or lyophilisation is by far the gentlest way to remove moisture from materials. The physical phenomenon of sublimation means a direct transition from the solid state to the vapour state without passing through the liquid state. The frozen material is dried under vacuum without thawing. This method can be used for a wide variety of applications: •• Preserving the characteristics of original substances in products (e.g. pharmaceutical products or milk) •• Preserving the original form (e.g. animal preparations, archaeological...

Freeze Drying / Lyophilisation Laboratory freeze dryer systems •• Ice condenser capacity 2 to 24 kg •• Mainly air-cooled chilling systems •• Broad range of accessories for a wide variety of applications Pilot freeze dryer systems •• Ice condenser capacity 6 to 16 kg •• Air-cooled or water-cooled chilling systems •• Freezing and drying in the drying chamber •• on shelves with liquid temperature control Production freeze drying systems •• Ice condenser capacity from 20 to 500 kg •• Water-cooled chilling systems •• Freezing and drying in the drying chamber •• on shelves with liquid temperature control...

Example Applications Accessories from Christ enable tailored solutions for individual applications. The modular system architecture makes adaptation to altered requirements easy, even a long time after the basic unit was acquired. The units in the Advanced series can be operated as one-chamber or two-chamber systems as desired with the appropriate accessories. Many accessories, such as acrylic chambers, can be used on basic units with capacities from 4 kg to 24 kg ice capacity. A number of example systems are described below.

Example Applications Starter package Accessories for our smallest unit, Alpha 1–2 LDplus, for drying in round-bottom flasks, wide-neck bottles or ampoules or on unheated shelves. Starter product package with Alpha 1–2 LDplus 3 shelves dia. 200 mm = 920 cm², distance between shelves 85 mm, additional ports for 8 flasks, round-bottom flasks and wide-neck bottles or distributor System Item number 4 Three unheated shelves 5 Acrylic drying chamber with 8 ports 7 Vacuum pump RZ-2,5 (2.25  m³/h)

Example Applications Routine package Accessories for the Beta series for drying in round-bottom flasks, wide-neck bottles or vials or on unheated shelves with relatively high specimen volume. Routine product package with Beta 2–8 LSCbasic Drying chamber with 24 ports for bottles, round-bottom flasks and wide-neck bottles or distributor for ampoules System Item number 5 Acrylic drying chamber 6 Extra acrylic drying chamber 7 Rubber valve for connecting vessels 8 Drip tray for acrylic drying chamber

Example Applications Pharmacy product package Accessories for the Alpha LSCplus series for carrying out the complete freeze drying process, including connection of crimp-seal vials under vacuum or inert gas. Pharmacy 1 product package with Alpha 2-4 LSCplus Freezing and drying ice condenser chamber (method A) cooled shelves with sealing device (dia. 200 mm, total area 0.031 m²) System Item number 1 Extension unit HED-16 LSCplus 2 Vacuum pump RZ-2,5 (2.25  m³/h) 4 Vacuum hose with standard flange couplings 5 Electromagnetic pressure control and stop valve 6 Sealing device integrated in acrylic...

Example Applications Dish Drying 1 product package Accessories for laboratory systems with LSCplus controller for drying relatively large specimen volumes in dishes or vessels (or in aluminium blocks if necessary). Dish Drying 1 product package with Alpha 1-4 LSCplus 10 heated shelves (dia. 200 mm; total area 0.31 m², distance between shelves 25 mm – can be adjusted by removing shelves) System Item number 1 Extension unit HED-16 LSCplus 4 Vacuum hose with standard flange couplings 5 Electromagnetic pressure control and stop valve 8 Shelves with rim, dia. 200 mm, with LyoBus-Modul 9 Acrylic drying...

Example Applications Pharmacy 2 product package Accessories for laboratory systems with LSCplus controller for drying relatively large product volumes in crimp-seal vials, including connection under vacuum or inert gas. Pharmacy 2 product package with Alpha 2-4 LSCplus 4 heated shelves with sealing device (dia. 250 mm, total area 0.18  m², distance between shelves 50 mm – can be adjusted by removing shelves) System Item number 1 Extension unit HED-16 LSCplus 4 Vacuum hose with standard flange couplings 5 Electromagnetic pressure control and stop valve 7 Sealing device with 1 shelf 9 Acrylic drying...