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FOR VACCINES IN BOTTLES

FOR VACCINES IN BOTTLES
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FOR VACCINES IN BOTTLES

Product catalog summary
Aseptic Processing Solutions
  • Internal Washing: Machines WR16 - WR24 are designed for washing and drying ampoules and vials, featuring ultrasonic pre-washing and water recycling, with outputs ranging from 3,000 to 24,000 pieces per hour.
  • Depyrogenation: DEPYR tunnels provide dry-heat sterilization with air recycling, suitable for ampoules and vials, maintaining outputs similar to washing machines.
  • Filling & Stoppering: STERY-LA and STERY-LC machines handle liquid or lyophilized products with inert gas flushing and integration capabilities with RABS or isolators.
  • Alu Capping: CAPSY-LC and ML670/12 machines offer low particle generation and automatic sealing pressure regulation.
  • External Decontamination: WRE machines provide external washing and drying with dedicated detergent circuits.
  • Coding: CODY machines offer versatile code printing positions with camera verification.
Inspection Solutions
  • Automatic Inspection and Leak Test Machines: RS1 and RS2 models perform inspections at speeds of 200 and 400 pieces per minute, respectively, with optional cosmetic and color controls.
  • Advanced Inspection: N450-LT model offers continuous motion inspection with a production output of 450 pieces per minute.
  • Inspection and Labelling: RS1-LAB and RS2-LAB models combine inspection with labelling, maintaining similar speeds to their inspection-only counterparts.
Labelling Solutions
  • Rotary Labeller Series: RL-F300 to RL-F800 models feature high-speed labelling with a rotary star wheel system and automatic tray loading.
  • Linear Labellers: SL-F425 and BL-F425 models provide easy access for maintenance and feature advanced control systems for reliable operations.
Secondary Packaging Solutions
  • Thermoforming Machines: FB220 for deep-draw tray forming.
  • Cartoner Series: MA80-N, MA155, MA255, and MA400 offer both intermittent and continuous motion options.
  • Casepacker and Palletizer: BESTPOCKET and MCP840 models include aggregation units for efficient packaging.
Key Points
  • All machines comply with GMP and FDA guidelines.
  • Wall installation allows maintenance in non-classified environments.
  • High-speed machines reduce changeover time and enhance process performance.
  • Innovative designs facilitate easy cleaning and reduce microbial contamination risks.
Labeling Machines:
Two models, BL-F425 and SL-F425, are designed for labeling with specifications for container size and label size. Both models accommodate product diameters of 15-90 mm and heights of 30-250 mm. Label dimensions range from 10-120 mm in height and 13-190 mm in length.
Secondary Packaging Solutions:
Includes cartoners, thermoformers, and end-of-line solutions. Machines feature adjustable speeds, tool-less changeovers, and options for heat-sealing stations. High-speed automatic feeding systems are available.
Thermoforming Machines:
Model FB220 is designed for pharmaceutical environments, capable of thermoforming trays for vials, ampoules, and syringes. It supports a maximum film index of 160 mm and film width of 184 mm.
Intermittent Motion Cartoner Series:
Model MA80-N is suitable for packaging vials, bottles, and trays. It offers versatility, a balcony design, and synchronized servo motors. Carton sizes range from 30-130 mm in width, 20-100 mm in height, and 75-200 mm in length.
Continuous Motion Cartoner Series:
Models MA155, MA255, and MA400 offer high-speed cartoning for vials, blisters, and bottles. They feature balcony designs, oil-bath main drive units, and motorized adjustments. Carton sizes vary across models, with the MA400 supporting up to 400 cartons per minute.
Casepacker with Aggregation Unit:
The Bestpocket model offers fast format changeovers and customizable outfeeds, supporting a wide range of products. It includes a DATAMATRIX verification camera and aggregation system.
Casepacker-Palletizer:
Model MCP840 combines case packing and palletizing in a compact unit, using robotic solutions and brushless motors for automation. It handles products with dimensions ranging from 20-150 mm in width, 15-120 mm in height, and 60-250 mm in length.
General Notes:
Specifications are subject to change without notice. The Marchesini Group updates products to meet market needs.
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Catalog excerpts

FOR VACCINES IN BOTTLES-1

PACKAGING MACHINERY SOLUTIONS FOR VACCINES IN BOTTLES

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FOR VACCINES IN BOTTLES-3

INTERNAL WASHING | WR16 - WR24 DEPYROGENATION | DEPYR FILLING & STOPPERING | STERY-LA - STERY-LC ALU CAPPING | CAPSY-LC - ML670/12 EXTERNAL DECONTAMINATION | WRE CODING | CODY 02 | INSPECTION SOLUTIONS 17 AUTOMATIC NSPECTION AND LEAKTEST MACHINE | RS1 - RS2 18 AUTOMATIC INSPECTION AND LEAK TEST MACHINE | N450-LT 19 AUTOMATIC INSPECTION, LEAK TEST AND LABELLING MACHINE RS1-LAB - RS2-LAB 03 | LABELLING SOLUTIONS 21 ROTARY LABELLER SERIES DOUBLE TRAY FEEDER TM3 | RL-F300 - 500 - 800 22 LINEAR LABELLERS | SL-F425 - BL-F425 DEEP-DRAW THERMOFORMING MACHINES | FB220 INTERMITTENT MOTION CARTONER SERIES...

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FOR VACCINES IN BOTTLES-4

THIS IS A UNIQUE CONCENTRATION OF RESEARCH, HOPE IN THE FUTURE, HUMANITY AND SENSE OF COMMUNITY. IT IS MARCHESINI GROUP’S COMMITMENT TO BEING A PART OF THE HUGE CHALLENGE WE MUST OVERCOME TOGETHER. TODAY MORE THAN EVER BEFORE. THIS IS OUR CONTRIBUTION TO A BETTER FUTURE.

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FOR VACCINES IN BOTTLES-5

OUR BATTLE IN A BOTTLE DISCOVER MARCHESINI GROUP’S PACKAGING LINES FOR VACCINES. Do you wish to kwow more? Scan QR code.

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FOR VACCINES IN BOTTLES-6

THE MARCHESINI GROUP DESIGNS AND BUILDS STAND-ALONE MACHINES AND CUSTOMIZED LINES FOR PACKAGING OF PHARMACEUTICALS AND COSMETICS. SINCE MASSIMO MARCHESINI ASSEMBLED HIS FIRST CARTONING MACHINE IN A GARAGE BACK IN 1974, THE GROUP HAS BEEN TRANSFORMED FROM A LOCAL BUSINESS INTO A “COMPACT” MULTINATIONAL ENTERPRISE, THANKS TO MERGERS AND ACQUISITIONS OF COMPLEMENTARY COMPANIES. TODAY, THE MARCHESINI GROUP CATERS FOR THE WHOLE PACKAGING PROCESS OF PHARMACEUTICALS AND COSMETICS, FROM START TO FINISH. THE FINISHED PRODUCT IS A COMBINATION OF CRAFTSMANSHIP INTEGRATED WITH ROBOTICS AND TECHNOLOGY. THIS...

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FOR VACCINES IN BOTTLES-7

Balcony-style facilitates innovative line installation, containers can be transported without friction, and cleaning surfaces is simple and easy. All machines comply with GMP and FDA Wall installation enables maintenance to be carried out from the back-side of the machines in a non-classified technical environment. New models are constantly being developed in our High-speed machines provide solutions aimed at reducing total changeover time and maximising the pharmaceutical process performance. Fully automated In Process Controls and containment cabinets in Isolation Technology have been implemented,...

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ASEPTIC PROCESSING SOLUTIONS VIALS

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01 ASEPTIC PROCESSING SOLUTIONS PACKAGING PROCESS PRIMARY PACKAGING SECONDARY PACKAGING INTERNAL WASHING INTERNAL WASHING BUNDLING BUNDLING FREEZE-DRYING (machine by third party) EXTERNAL DECONTAMINATION PLASTIC TRAY PACKAGING PAPER BOARD TRAY PACKAGING VISUAL INSPECTION TRAY PACKAGING INTO CARTON

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MACHINE SOLUTIONS INTERNAL WASHING WR16 - WR24 Rotary continuous motion machines for internal washing and drying of ampoules and vials for Small Volume Parenteral (SVP). • 8 internal and 3 external washing/blowing stations • Pre-washing in Ultrasonic Bath • Water Recycling • Automatic drainage and drying • Container siliconizing OUTPUT 3.000 / 24.000 pcs / h PRODUCT RANGE Ampoules 1 ml / 25 ml Vials 2R / 500 ml MADE BY CO

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FOR VACCINES IN BOTTLES-11

01 ASEPTIC PROCESSING SOLUTIONS DEPYROGENATION DEPYR Depyrogenation Tunnels for ampoules and vials for Small Volume Parenteral (SVP). • Hot chamber with dedicated make-up unit and air-flow control • Automatic balancing and air flow adjustment • Pressure cascade according to process requirements • Outfeed chamber with dedicated cooling coil and 100% air recycling • Dry-Heat sterilization of outfeed chamber OUTPUT 3.000 / 24.000 pcs / h PRODUCT RANGE Ampoules 1 ml / 25 ml Vials 2R / 500 ml MADE BY

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FOR VACCINES IN BOTTLES-12

MACHINE SOLUTIONS FILLING & STOPPERING STERY-LA - STERY-LC Filling and stoppering machines for liquid or lyo products, suitable for filling vials for Small Volume Parenteral (SVP) in an aseptic process with complete or partial closure using rubber stoppers. • Intermittent or continuous motion • Balcony or traditional table-top arrangement • Statistical or 100% weight check In Process Control (IPC) • Dosing system: rotary piston and/or peristaltic pumps • Inert gas flushing • Easy integration with RABS or Isolator • Cleaning and Sterilization in Place (CIP/SIP) OUTPUT 3.000 / 24.000 pcs / h PRODUCT...

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FOR VACCINES IN BOTTLES-13

01 ASEPTIC PROCESSING SOLUTIONS ALU CAPPING CAPSY-LC - ML670/12 Alu Cap sealing machines for liquid or lyo products, suitable for closing vials for Small Volume Parenteral (SVP) in an aseptic process. • Intermittent or continuous motion • Balcony or traditional table-top arrangement • Automatic Sealing Pressure Regulation • Low particle generation • Easy integration with RABS or Isolator OUTPUT 3.000 / 24.000 pcs / h PRODUCT RANGE Vials 2R / 125 ml MADE BY CO

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FOR VACCINES IN BOTTLES-14

MACHINE SOLUTIONS EXTERNAL DECONTAMINATION WRE Rotary continuous motion machines for external washing and drying of ampoules and vials for Small Volume Parenteral (SVP). • Cabinet and duct washing with spray-balls and manual spray-guns • Automatic drainage and drying • Dedicated detergent circuit • Bag-In / Bag-Out filters OUTPUT up to 24.000 pcs / h PRODUCT RANGE Ampoules 1 ml / 25 ml Vials 2R / 125 ml MADE BY CORI

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01 ASEPTIC PROCESSING SOLUTIONS CODING CODY Continuous motion machines for printing codes on vials or caps/seals with camera verification. • Different code printing positions possible - shoulder, body or bottom of vials; lateral or top side of caps/seals • Vials transferred by a screw to main starwheel for coding and checking operations • Vials are held by vacuum systems in the main starwheel to ensure uniform printing and maximum control precision • Printing head and camera height automatically adjusted from the HMI • Vial collection in trays OUTPUT up to 24.000 pcs / hr PRODUCT RANGE Cartridges...

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INSPECTION SOLUTIONS VIALS

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AUTOMATIC INSPECTION AND LEAK TEST MACHINE RS1 200 PCS/MIN - RS2 400 PCS/MIN Automatic inspection machines based on intermittent motion technology performing tip/cap control, particles, fill level and leak test inspection of injectable products. Main features: • Product range: Ampoules, vials, cartridges from 1 ml to 30 ml • Production output: 200 pcs/min (RS1), 400 pcs/ min (RS2) • Easy mechanics Standard inspection: • Extraneous reflecting and no reflecting particles, fibres,glasses • Correct filling level • Leak Test Optional Inspections: • Tip/cap cosmetic control (shape, height, black spots,...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.